| TIE | transient ischemic episode |
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| AChRs | Acetylcholine Receptors |
| RA | radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal... |
| RITARD | Removable Intestinal Tie Adult Rabbit Diarrhoea |
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| TIE | Toxicity Identification Evaluation |
| AR | Alpha1-adrenergic receptors |
| alpha1-ARs | Alpha1-adrenergic receptors |
| beta 2AR | Beta 2-adrenergic receptors |
| tie | 1. To fasten with a band or cord and knot; to bind. "Tie the kine to the cart." "My son, keep thy father's commandment, and forsake not the law of thy mother: bind them continually upon thine heart, and tie them about thy neck." (Prov. Vi. 20,21) 2. To form, as a knot, by interlacing or complicating a cord; also, to interlace, or form a knot in; as, to tie a cord to a tree; to knit; to knot. "We do not tie this knot with an intention to puzzle the argument." 3. To unite firmly; to fasten; to hold. "In bond of virtuous love together tied." (Fairfax) 4. To hold or constrain by authority or moral influence, as by knotted cords; to oblige; to constrain; to restrain; to confine. "Not tied to rules of policy, you find Revenge less sweet than a forgiving mind." (Dryden) 5. To unite, as notes, by a cross line, or by a curved line, or slur, drawn over or under them. 6. To make an equal score with, in a contest; to be even with. To ride and tie. See Ride. To tie down. To fasten so as to prevent from rising. To restrain; to confine; to hinder from action. To tie up, to confine; to restrain; to hinder from motion or action. Origin: OE. Tien, teyen, AS. Tigan, tiegan, fr. Teag, teah, a rope; akin to Icel. Taug, and AS. Teon to draw, to pull. See Tug, and cf. Tow to drag. Origin: AS. Tege, tge, tige. 64. See Tie. 1. A knot; a fastening. 2. A bond; an obligation, moral or legal; as, the sacred ties of friendship or of duty; the ties of allegiance. "No distance breaks the tie of blood." (Young) 3. A knot of hair, as at the back of a wig. 4. An equality in numbers, as of votes, scores, etc, which prevents either party from being victorious; equality in any contest, as a race. 5. A beam or rod for holding two parts together; in railways, one of the transverse timbers which support the track and keep it in place. 6. A line, usually straight, drawn across the stems of notes, or a curved line written over or under the notes, signifying that they are to be slurred, or closely united in the performance, or that two notes of the same pitch are to be sounded as one; a bind; a ligature. 7. Low shoes fastened with lacings. Bale tie, a fastening for the ends of a hoop for a bale. Source: Websters Dictionary (01 Mar 1998) |
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| TIE-2 receptor tyrosine kinase | <enzyme> Expressed in developing vascular endothelial cells; unlike tie-1, also expressed in lens epithelium and heart epicardium; has the same organization of amino acid sequence motifs characteristic of tie-1; aa sequence of the intracellular and extracellular regions of tie-1 and tie-2 are 79% and 32% identical, respectively; aa sequence of both kinases given in first source Registry number: EC 2.7.10.- Synonym: tie-2-rtk (26 Jun 1999) |
| tie-over dressing | A dressing placed over a skin graft or other sutured wound and tied on by the sutures which have been left of sufficient length for that purpose. Synonym: bolus dressing. (05 Mar 2000) |
| tie receptor tyrosine kinase | <enzyme> From human leukaemia cells; expressed in developing vascular endothelial cell; has homology with egf, bfgf, csf-1, pdgf and stem cell factor receptors; ligand and biologic function not known as of 12/92; tie-1 receptor tyrosine kinase is rat homolog of tie receptor tyrosine kinase; aa sequence known Registry number: EC 2.7.10.- Synonym: tie-1 receptor tyrosine kinase, tie-1 rtk (26 Jun 1999) |
| tongue-tie | <medicine> Impeded motion of the tongue because of the shortness of the fraenum, or of the adhesion of its margins to the gums. Source: Websters Dictionary (01 Mar 1998) |
| adrenergic receptors | Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibres of the sympathetic nervous system. Such receptor's can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptor's are divided into alpha-receptor's and beta-receptor's, on the basis of their response to various adrenergic activating and blocking agents. Synonym: adrenoceptor, adrenoreceptors. (05 Mar 2000) |
| alpha-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles. (05 Mar 2000) |
| ANP clearance receptors | Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action. (05 Mar 2000) |
| ANP receptors | Cell surface receptors for atrial natriuretic peptide that have a single transmembrane spanning element; these have integral kinase and guanylate cyclase domains. (05 Mar 2000) |
| B-cell antigen receptors | In the primary immune response immunoglobulin D and monomeric immunoglobulin M are the B-cell antigen receptors. On memory B-cells, other immunoglobulin molecules can serve as antigen receptors. (05 Mar 2000) |
| beta-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as propranolol, to block only some adrenergic receptor's and of other agents, such as isoproterenol, to activate only the same adrenergic receptor's. Such receptor's are designated as beta-receptors. Their activation results in physiological responses such as increases in cardiac rate and force of contraction (b1), and relaxation of bronchial and vascular smooth muscle (b2). (05 Mar 2000) |
| mannose-6-phosphate receptors | Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind. (05 Mar 2000) |
| receptors, adrenergic | Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of g-proteins with which they bind; this scheme does not respect the alpha-beta distinction. (12 Dec 1998) |
| receptors, adrenergic, alpha | One of the two major pharmacological subdivisions of adrenergic receptors. The alpha-beta distinction was originally based on cellular effects of receptor activation but now relies on the relative affinities for certain synthetic ligands. Alpha-adrenergic receptors are further subdivided into several subclasses based on studies of endogenous and cloned receptors. (12 Dec 1998) |
| receptors, adrenergic, alpha-1 | A subclass of alpha-adrenergic receptors (receptors, adrenergic, alpha). Alpha-1 adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist phenylephrine and the antagonist prazosin. They are widespread, with clinically important concentrations in the liver, the heart, vascular, intestinal, and genitourinary smooth muscle, and the central and peripheral nervous systems. (12 Dec 1998) |
Synonyms : Receptor Tyrosine Kinase TIE, TIE Receptor Family, TIE Receptor Tyrosine Kinase, Family, TIE Receptor, Receptor Family, TIE, TIE Receptors
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