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  • COS cell
    COS ¼¼Æ÷(á¬øà)
  • cos site
    cos ÀÚ¸®
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COS cheiro-oral syndrome; chief of staff; Clinical Orthopaedic Society; clinically observed seizures
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COS Carbonyl sulfide
COS Childhood-onset schizophrenia
cos cohesive end
cos cohesive end site
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COS cell <cell culture> A cell line derived from the african green monkey and used for transfection and cloning. The cells are simian fibroblasts (CV 1 cells) transformed by SV40 that is deficient in the origin of replication region.
They express large T antigen constitutively and if transfected with a vector containing a normal SV40 origin have all the other early viral genes necessary to generate multiple copies of the vector and thus to give very high levels of expression.
(04 Jul 1999)
cos site <molecular biology> A 12-nucleotide bases-long segment of single stranded DNA that exists at both ends of the bacteriophage lambda's double-stranded genome.
The two cos sites at the ends of the genome are complementary to one another so that the genome can become circular once the virus has infected a host bacterium. The circular genome can then be duplicated continuously until there are many repeats of it strung together, the cos sites show the virus where to cut them apart right before they are packaged into individual capsids as new progeny viruses ready to infect more host cells.
(10 Nov 1998)
Hippocrates of Cos Greek physician, called the "Father of Medicine," circa 460-377 B.C.
See: hippocratic facies, hippocratic fingers, hippocratic nails, school, succussion.
(05 Mar 2000)
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Praxagoras of Cos a Greek physician, c. 340 B.C., who succeeded Diocles as leader of the Dogmatists. He was apparently the first Greek physician to recognize the difference between arteries (carriers of air) and veins (carriers of blood), and to comment on the pulse.
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