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PEG 14C-polyethylene glycol
TPGS D-alpha-tocopheryl polyethylene glycol 1,000 succinate
mPEG Monomethoxy polyethylene glycol
PEG-SOD Polyethylene Glycol-Superoxide Dismutase
PEG 4000 Polyethylene glycol
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polyethylene glycol <chemical> A hydrophilic polymer that interacts with cell membranes and promotes fusion of cells to produce viable hybrids. Often used in producing hybridomas.
(18 Nov 1997)
polyethylene glycol dehydrogenase <enzyme> Catalyses the first step in polyethylene glycol metabolism in bacteria
Registry number: EC 1.1.1.-
(26 Jun 1999)
polyethylene glycol-glutaminase-asparaginase <chemical> Covalent attachment of polyethylene glycol to nonessential amine groups of enzyme renders it nonimmunogenic for treatment of leukaemia (EC 3.5.1.-)
Pharmacological action: immunosuppressive agent
Chemical name: glutaminase-asparaginase
Synonym: polyethyleneglycol-l-glutaminase-l-asparaginase, peg-l-glutaminase-l-asparaginase
(26 Jun 1999)
polyethylene glycol-superoxide dismutase <chemical> A free radical scavenger
Pharmacological action: free radical scavengers
Synonym: peg-sod
(26 Jun 1999)
polyethylene glycol-uricase <chemical> Uricase covalently attached to polyethylene glycol, modifying 71% of amino groups and retaining 11% of activity without eliciting antibody response in mice or man; used for lowering serum uric acid
Synonym: peg-uricase, methoxypolyethylene glycol uricase
(26 Jun 1999)
polyethylene glycols <chemical> Alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyls). Additional polymers of ethylene oxide and water and their ethers. They vary in consistency from liquid to solid, depending on the molecular weight, indicated by a number following the name. Used as surfactants in industry, including foods, cosmetics and pharmaceutics; in biomedicine, as dispersing agents, solvents, ointment and suppository bases, vehicles, tablet excipient. Some specific groups are lauromagrogols, nonoxynols, octoxynols and poloxamers.
Pharmacological action: excipient, pharmaceutic aid, solvents, surface-active agent, vehicles.
(12 Dec 1998)
polyethylene terephthalates Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibres that are pressed into meshes or woven into fabrics.
(12 Dec 1998)
glycol <chemistry> A thick, colourless liquid, C2H4(OH)2, of a sweetish taste, produced artificially from certain ethylene compounds. It is a diacid alcohol, intermediate between ordinary ethyl alcohol and glycerin.
Any one of the large class of diacid alcohols, of which glycol proper is the type.
Origin: Glycerin + -ol. See Glycerin.
Source: Websters Dictionary
(01 Mar 1998)
glycol ethers Chemicals such as ethylene glycol monomethyl ether and ethylene glycol monoethyl ether; they are teratogens which induce testicular atrophy in animals.
(05 Mar 2000)
monomethoxypolyethylene glycol-arginase <chemical> Monomethylethylene glycol and arginase are attached covalently
Pharmacological action: antineoplastic agent
Synonym: mm-peg-arginase
(26 Jun 1999)
monomethoxypolyethylene glycol-conjugated asparaginase <chemical> Used in patients with haematological malignancies
Synonym: peg(2)-asp, 2,4-bis(2-methoxypolyethyleneglycol)-6-chloro-s-triazine-conjugated l-asparaginase
(26 Jun 1999)
monomethoxypolyethylene glycol-superoxide dismutase <chemical>
Pharmacological action: free radical scavengers
Synonym: mpeg-sod
(26 Jun 1999)
propylene glycol <chemical> A clear, colourless, viscous liquid used as a humectant and solvent in pharmaceutical preparations.
Derivative of propylene glycol (1,2-propanediol). They are used as humectants and solvents in pharmaceutical preparations.
Pharmacological action: cryoprotective agents, solvents, vehicles.
(12 Dec 1998)
diethylene glycol An organic solvent chemically related to ethylene glycol. Upon metabolic conversion it becomes oxalic acid, which is toxic to the kidney. A sweet, viscous liquid that was used to make the infamous elixir of sulfanilamide that proved fatal to over 100 children in 1937, leading to the establishment of the FDA to monitor drug safety.
(05 Mar 2000)
triethylene glycol C6H14O4; 2,2'-Ethylenedioxybis(ethanol);used in the vapor state as an air-sterilizing agent; toxic to bacteria, fungi, and viruses in very low concentrations in air; variations in the humidity of the air limit the germicidal effectiveness.
(05 Mar 2000)
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