| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
|---|---|
| AXL | anexelekto [oncogene]; axillary lymphoscintigraphy |
| c-onc | cellular oncogene |
| ONC | oncogene; oncology; Orthopaedic Nursing Certificate; over-the-needle catheter |
| src | Rous sarcoma oncogene |
| c-onc | cellular oncogene |
|---|---|
| GRO-alpha | Growth Regulated Oncogene-alpha |
| GROalpha | Growth-related oncogene-alpha |
| proto-oncogene proteins c-erbb-2 | Cellular proteins in the epidermal growth factor receptor family encoded by the c-erbb genes. These proteins are overexpressed in a significant portion of adenocarcinomas found at various sites, especially in the breast. Gene amplification appears to be the predominant method leading to overexpression. (12 Dec 1998) |
|---|---|
| oncogene proteins v-erbb | Transforming proteins encoded by erbb oncogenes from the avian erythroblastosis virus. The protein is a truncated form of the egf receptor (receptors, epidermal growth factor-urogastrone) whose kinase domain is constitutively activated by deletion of the ligand-binding domain. (12 Dec 1998) |
| genes, erbb | Retrovirus-associated DNA sequences (erbb) originally isolated from, or related to, the avian erythroblastosis virus (aev). These genes code for the epidermal growth factor receptor (egfr) family of receptors which is important in the control of normal cell proliferation and in the pathogenesis of human cancer. The genes include erbb-1 (genes, erbb-1), erbb-2 (genes, erbb-2), and erbb-3, all of which show abnormalities of expression in various human neoplasms. (12 Dec 1998) |
| genes, erbb-1 | Retrovirus-associated DNA sequences (erbb) originally isolated from the avian erythroblastosis virus (aev). The oncogene v-erbb arose by insertion of viral DNA into the c-erbb-1 proto-oncogene resulting in expression of a protein lacking the amino-terminal ligand-binding domain. V-erbb is the primary transforming gene of aev and abrogates the requirements for other mitogens. The proto-oncogene c-erbb-1 codes for the protein epidermal growth factor receptor (epidermal growth factor receptor-urogastrone). Overexpression of the gene occurs in a wide range of tumours, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbb-1 gene is located at 7p12-13 on the short arm of chromosome 7. (12 Dec 1998) |
| genes, erbb-2 | Retrovirus-associated DNA sequences (erbb) related to the c-erbb-1 gene and identified by probes from c-erbb-1 or its avian viral homologue v-erbb. The proto-oncogene erbb-2 (c-erbb-2) codes for a protein that has structural features indicative of a growth factor receptor with close similarity to the epidermal growth factor (egf) receptor. Overexpression and amplification of the gene is associated with adenocarcinomas and with poor prognosis in breast carcinomas. The human c-erbb-2 gene is located at 17p12-21 on the short arm of chromosome 17. (12 Dec 1998) |
| recessive oncogene | <molecular biology> A single copy of this gene issufficient to suppress cell proliferation, the loss of both copies of the gene contributes to cancer formation. (09 Oct 1997) |
| viral oncogene | <molecular biology> A viral gene that contributes to cancer development in vertebrate hosts. (09 Oct 1997) |
| cellular oncogene | <molecular biology> A normal gene that, when mutated or improperly expressed, can cause cancer to develop. (09 Oct 1997) |
| c-oncogene | <molecular biology> A normal gene which has a tumour-producing insert that may have originated from a virus in it, turning it into a proto-oncogene. When these genes are sufficiently mutated, amplified, or over-expressed (transcribed too many times), they can begin to produce cancers. (05 Jan 1998) |
| proto-oncogene | <molecular biology> The normal, cellular equivalent of an oncogene, thus usually a gene involved in the signalling or regulation of cell growth. In general, cellular proto-oncogenes are prefixed with a c, rather than their abnormal viral counterparts, that are prefixed with a v, for example c myc and v myc. They are fragments of DNA, related to oncogenes but are the normal switches used to control growth and tissue repair. (06 Oct 1997) |
| proto-oncogene protein p21(ras) | Cellular protein encoded by the c-ras genes. The protein has GTPase activity and is involved in transmembrane signal transduction as a guanine nucleotide binding protein. Elevated levels of p21 c-ras have been associated with neoplasia. (12 Dec 1998) |
| proto-oncogene protein pp60(c-src) | <enzyme> Membrane-associated tyrosine-specific kinase encoded by the c-src genes. It has an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to pp60(v-src) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase. Registry number: EC 2.7.1.- (12 Dec 1998) |
| proto-oncogene proteins | Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity. (12 Dec 1998) |
| proto-oncogene proteins c-abl | Membrane proteins encoded by the c-abl genes. They exhibit tyrosine kinase activity and play a role in normal haematopoiesis especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific n-terminal amino acids are deleted, releasing the kinase from negative regulation. (12 Dec 1998) |
| proto-oncogene proteins c-bcl-2 | Membrane proteins encoded by the bcl-2 genes and serving as a potent inhibitor of cell death by apoptosis. The proteins are found on mitochondrial, microsomal, and nuclear membrane sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma. (12 Dec 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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