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  • transdermal delivery
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PP diphosphate group; emphysema [pink puffers]; near point of accommodation [Lat. punctum proximum]; pa...
TD tabes dorsalis; tardive dyskinesia; T-cell dependent; temporary disability; terminal device; tetanus...
TIS tetracycline-induced steatosis; transdermal infusion system; triage illness scale; trypsin-insoluble...
TTS tarsal tunnel syndrome; temporary threshold shift; through the scope; through the skin; tilt table s...
NG nasogastric; neoplastic growth; new growth; nitroglycerin; nodose ganglion; no growth; not given
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TTS Transdermal Therapeutic System
NG Nitroglycerin
NTG Nitroglycerin
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  • transdermal
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transdermal <pharmacology> Entering through the dermis or skin, as in administration of a drug applied to the skin in ointment or patch form.
(17 Mar 1998)
nitroglycerin <chemistry> A liquid appearing like a heavy oil, colourless or yellowish, and consisting of a mixture of several glycerin salts of nitric acid, and hence more properly called glycerin nitrate.
It is made by the action of nitric acid on glycerin in the presence of sulphuric acid. It is extremely unstable and terribly explosive. A very dilute solution is used in medicine as a neurotic under the name of glonion.
A great number of explosive compounds have been produced by mixing nitroglycerin with different substances; as, dynamite, or giant powder, nitroglycerin mixed with siliceous earth; lithofracteur, nitroglycerin with gunpowder, or with sawdust and nitrate of sodium or barium; Colonia powder, gunpowder with nitroglycerin; dualin, nitroglycerin with sawdust, or with sawdust and nitrate of potassium and some other substances; lignose, wood fibre and nitroglycerin.
Pharmacologic action: Relaxes smooth muscle - dilates veins, dilates coronary arteries, reduces left ventricular filling pressure, lowers systemic vascular resistance, decreases myocardial oxygen demand.
Uses: Treat angina pectoris.
Dose: One tablet (0.3 to 0.4 mg) sublingual, may repeat twice at 5 minute intervals Intravenous infusion: 0.5 - 2 mcg/kg per min.
Potential complications: May cause hypotension, especially if hypovolemic; headache is common.
Alternative forms: nitroglycerine.
Origin: Nitro- + glycerinn.
(17 Mar 2000)
nitroglycerin reductase <enzyme> Pseudomonas fmn-containing enzyme that catalyses NADPH-dependent denitration of nitroglycerin, yielding nitrite
Registry number: EC 1.7.99.-
(26 Jun 1999)
Bayer's patches Sites of adhesion between the outer and cytoplasmic membranes of gram-negative bacteria.
(18 Nov 1997)
Gottron's patches <clinical sign> Gottron's patches are scaly, patchy redness over the knuckles and is seen in patients with dermatomyositis, an inflammatory muscle disorder. (see polymyositis).
(20 Sep 2002)
Peyer's patches Lymphoid organs located in the sub mucosal tissue of the mammalian gut containing very high proportions of IgA secreting precursor cells. The patches have B and T dependent regions and germinal centres. A specialised epithelium lies between the patch and the intestine. Involved in gut associated immunity.
(18 Nov 1997)
cotton-wool patches <clinical sign, ophthalmology> White, fuzzy areas on the surface of the retina (accumulations of cellular organelles) caused by damage (usually infarction) of the retinal fibre layer.
Synonym: cotton-wool spots.
(05 Mar 2000)
salmon patches Red or purple-coloured vascular skin markings that develop shortly after birth. most are usually painless and benign. Some lesions (cavernous haemangiomas) will disappear or become harder to see as the child approaches school age. Localised steroid injections have been used successfully to reduce the size of a birthmark.
(27 Sep 1997)
shagreen patches <radiology> Normal-coloured plaques on trunk with firmer texture than normal skin, associated with tuberous sclerosis
(12 Dec 1998)
smoker's patches An obsolete term for leukoplakia.
(05 Mar 2000)
soldier's patches White plaques of hyalinised fibrous tissue situated in the epicardium overlying the right ventricle of the heart where it is not covered by lung.
Synonym: soldier's patches.
White macroscopic areas in the omentum, due to accumulation of macrophages and lymphocytes.
Synonym: tache laiteuse.
(05 Mar 2000)
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