| N5,N10-methenyltetrahydrofolate | A one-carbon derivative of tetrahydrofolate; used in purine biosynthesis. N5,N10-methylenetetrahydrofolate reductase, an enzyme that converts N5,N10-m ethylenetetrahydrofolate to N5,N10-methyl enyltetrahydrofolate using NADP+; a deficiency of this enzyme results in an accumulation of l-homocysteine and severe neurological disturbances. (05 Mar 2000) |
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