| VH | variable domain of heavy chain; variable heavy chain |
|---|---|
| PKCSH | protein kinase C heavy chain |
| AK | above knee; acetate kinase; adenosine kinase; adenylate kinase; artificial kidney |
| CK | calf kidney; casein kinase; chicken kidney; cholecystokinin; choline kinase; contralateral knee; cre... |
| TK | thymidine kinase; transketolase; triose-kinase; tyrosine kinase |
| 4F2HC | 4F2 heavy chain |
|---|---|
| Dhc | Dynein heavy chain |
| HC | Heavy chain |
| HCD | Heavy chain diseases |
| IGH | Ig heavy chain |
creatine kinase
| MyoD heavy chain kinase | <enzyme> Required for actin activation of the magnesium atpase activity of dictyostelium myosin id (myod); specific for myod Registry number: EC 2.7.1.- Synonym: 110-kD protein kinase, dictyostelium, dictyostelium 110-kD protein (26 Jun 1999) |
|---|
| gene rearrangement, b-lymphocyte, heavy chain | Ordered rearrangement of b-lymphocyte variable gene regions thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the immature b-lymphocyte. (12 Dec 1998) |
|---|---|
| myosin heavy chain | <protein> See myosin: do not confuse with heavy meromyosin which is a subfragment of the heavy chain of myosin II. (18 Nov 1997) |
| heavy chain | <protein> In general, the larger polypeptide in a multimeric protein. Thus the immunoglobulin heavy chain is of 50 kD, the light chain of 22 kD, whereas in myosin the heavy chain is very much larger (220 kD) than the light chains (~20 kD). (18 Nov 1997) |
| heavy chain disease | A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the n- (amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (v) and constant (c) region genes. (12 Dec 1998) |
| immunoglobulins, heavy-chain | Major components of immunoglobulin molecules. They are the larger of the two types of polypeptide chains responsible for the biological and immunological properties of the different immunoglobulins. They differ according to the class of ig from which they were isolated, contain 450 to 600 amino acid residues per chain, and have molecular weights of 51-72 kD. One ig molecule comprises two heavy and two light chains. (12 Dec 1998) |
| myoD | <molecular biology> Stands for myogenic determination. MyoD was described as a master regulatory gene for the determination of muscle cells, but muscle determination is now thought to involve a family of genes. It is normally only expressed in myoblasts and skeletal muscle cells, but if transfected into cells will convert many differentiated cells into muscle cells. The myoD gene codes for the myoD protein which then switches on the the transcription of many muscle specific genes. MyoD is a member of a family of genes that all code for nuclear proteins which have a basic DNA binding motif and a helix loop helix dimerisation domain (bHLH or mHLH proteins, b=basic, m=myogenic). They bind to a consensus sequence CANNTG and can form homodimers or heterodimers with other members of the bHLH superfamily. (18 Nov 1997) |
| myod protein | A myogenic regulatory factor that controls myogenesis. Though it is not clear how its function differs from the other myogenic regulatory factors, myod appears to be related to fusion and terminal differentiation of the muscle cell. (12 Dec 1998) |
| MAP kinase kinase kinase | <enzyme> From pc12 cells; reactivates map kinase kinase inactivated by protein phosphatase 2a by phosphorylation of serine residues; tak1 (tgf-beta-activated kinase 1) is a member of the mapkkk family; genbank ab006787 (mouse) Registry number: EC 2.7.10.- Synonym: mapkkk, tak1 mapkkk, ask1 (kinase), apoptosis signal-regulating kinase 1 (26 Jun 1999) |
| chain, orthodontic chain | <dentistry> A stretchable plastic chain used to hold archwires into brackets and to moke teeth. (08 Jan 1998) |
| branched-chain fatty-acid-kinase | <enzyme> From anaerobic spirochete ma-2 Registry number: EC 2.7.2.14 Synonym: isovalerate kinase, 2-methylbutyrate kinase, isobutyrate kinase (26 Jun 1999) |
| myosin light chain kinase | <enzyme> An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and calmodulin. The 20-kD light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction. Chemical name: ATP:myosin-light-chain O-phosphotransferase Registry number: EC 2.7.1.117 (12 Dec 1998) |
| metals, heavy | metals with high specific gravity, typically larger than 5. They have complex spectra, form coloured salts and double salts, have a low electrode potential, are mainly amphoteric, yield weak bases and weak acids, and are oxidizing or reducing agents (12 Dec 1998) |
| myosin heavy chains | The heavy chains of the muscle protein myosin. Each molecule of myosin is composed of two heavy chains and two pairs of light chains. The heavy chains have a molecular weight of about 230 kD and each heavy chain is associated with a dissimilar pair of light chains. (devlin, textbook of biochemistry: with clinical correlations, 3rd ed, p957) (12 Dec 1998) |
| heavy | 1. Heaved or lifted with labour; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught. 2. Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc. "The hand of the Lord was heavy upon them of Ashdod." (1 Sam. V. 6) "The king himself hath a heavy reckoning to make." (Shak) "Sent hither to impart the heavy news." (Wordsworth) "Trust him not in matter of heavy consequence." (Shak) 3. Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment. "The heavy [sorrowing] nobles all in council were." (Chapman) "A light wife doth make a heavy husband." (Shak) 4. Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book. "Whilst the heavy plowman snores." (Shak) "Of a heavy, dull, degenerate mind." (Dryden) "Neither [is] his ear heavy, that it can not hear." (Is. Lix. 1) 5. Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like. 6. Loud; deep; said of sound; as, heavy thunder. "But, hark! that heavy sound breaks in once more." (Byron) 7. Dark with clouds, or ready to rain; gloomy; said of the sky. 8. Impeding motion; cloggy; clayey; said of earth; as, a heavy road, soil, and the like. 9. Not raised or made light; as, heavy bread. 10. Not agreeable to, or suitable for, the stomach; not easily digested; said of food. 11. Having much body or strength; said of wines, or other liquors. 12. With child; pregnant. Heavy artillery. <chemistry> See Metal. Heavy weight, in wrestling, boxing, etc, a term applied to the heaviest of the classes into which contestants are divided. Cf. Feather weight, under Feather. Heavy is used in composition to form many words which need no special explanation; as, heavy-built, heavy-browed, heavy-gaited, etc. Origin: OE. Hevi, AS. Hefig, fr. Hebban to lift, heave; akin to OHG. Hebig, hevig, Icel. Hofigr, hofugr. See Heave. Source: Websters Dictionary (01 Mar 1998) |
| heavy hydrogen | <radiobiology> Somewhat informal alternative name for deuterium. See: deuterium. (10 Jan 1998) |
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|