| 영문 | cytokine | 한글 | 시토카인 |
|---|---|---|---|
| 설명 | 조직의 국소에서 생산되어서 국소의 세포간의 신호전달을 매개하는 단백질 인자의 총칭이다. 표적세포의 수용체에 결합해서 세포내 활성화 메커니즘을 발현시키는 것으로 면역반응의 제어, 항암작용, 항바이러스작용, 세포의 증식-분화의 조절 등의 작용을 나타낸다. 일반적으로 10－12~10－10 몰의 극히 미량에서 기능하며 신속히 분해소실된다. 림프구가 분비하는 림포카인, 큰포식세포 유래의 모노카인, T세포가 분비하는 인터루킨 등의 여러 종류가 알려지고 있으나 각각의 유전자의 해명으로 동일한 것이 판명되고 있다. |
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| CSIF | cytokine synthesis inhibitory factor |
|---|---|
| CRF | case report form; chronic renal failure; chronic respiratory failure; coagulase-reacting factor; con... |
| MIF | macrophage inhibitory factor; melanocyte[-stimulating hormone]-inhibiting factor; maximum inspirator... |
| MMIF | macrophage migration inhibitory factor |
| MAF | macrophage activation factor; macrophage agglutinating factor; maximum atrial fragmentation; minimum... |
| MIP-1 alpha | macrophage inhibitory protein 1 alpha |
|---|---|
| CINC | 8/cytokine-induced neutrophil chemoattractant |
| CrmA | Cytokine response modifier A |
| CIK | Cytokine-induced killer |
| CINC-1 | Cytokine-induced neutrophil chemoattractant-1 |
| macrophage migration-inhibitory factors | Proteins released by sensitised lymphocytes and possibly other cells that inhibit the migration of macrophages away from the release site. The structure and chemical properties may vary with the species and type of releasing cell. (12 Dec 1998) |
|---|---|
| receptors, cytokine | Cell surface proteins that bind cytokines and trigger intracellular changes influencing the behaviour of cells. (12 Dec 1998) |
| cytokine | <biochemistry> Small proteins or biological factors (in the range of 5-20 kD) that are released by cells and have specific effects on cell-cell interaction, communication and behaviour of other cells. Not really different from hormones, but the term tends to be used as a convenient generic shorthand for interleukins, lymphokines and several related signalling molecules such as TNF and interferons. Generally growth factors would not be classified as cytokines, though TGF is an exception. Rather an imprecise term. Chemokines are a subset of cytokines. (29 Sep 1997) |
| gastric inhibitory polypeptide | <hormone> Peptide hormone (43 amino acids) that stimulates insulin release and inhibits the release of gastric acid and pepsin. Acronym: GIP (18 Nov 1997) |
| G-protein, inhibitory GI | A g-protein that inhibits adenylyl cyclase and activates k+ channels. (12 Dec 1998) |
| migration-inhibitory factor | <growth factor> A soluble, nondialysable factor that is produced by sensitised lymphocytes following exposure to a specific antigen. It inhibits macrophage migration and causes adherence. It was originally defined on the basis of inhibition of emigration of mononuclear cells from capillary (haematocrit) tubes, more recently a 13 kD protein with migration inhibitory activity has been isolated. Acronym: MIF Synonym: inhibition factor. (22 Sep 2002) |
| migration-inhibitory factor test | A test which measures the presence of migration-inhibitory factor. Usually peritoneal macrophages are placed in a capillary tube in the presence or absence of supernatants from activated T-cells. If MIF is present, the migration of monocyte/macrophages is reduced. Synonym: macrophage migration inhibition test, migration inhibition test. (05 Mar 2000) |
| minimal inhibitory concentration | <microbiology, pharmacology> The lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro. (05 Mar 2000) |
| inhibitory | Of or pertaining to, or producing, inhibition; consisting in inhibition; tending or serving to inhibit; as, the inhibitory action of the pneumogastric on the respiratory center. "I would not have you consider these criticisms as inhibitory. <physiology> " (Lamb) Inhibitory nerves, those nerves which modify, inhibit, or suppress a motor or secretory act already in progress. Origin: LL. Inhibitorius: cf. F. Inhibitoire. Source: Websters Dictionary (01 Mar 1998) |
| inhibitory fibres | Nerve fibre's that inhibit the activity of the nerve cells with which they have synaptic connections, or of the effector tissue (smooth muscle, heart muscle, glands) in which they terminate. (05 Mar 2000) |
| inhibitory junction potential | Hyperpolarization of smooth muscle produced by stimulation of inhibitory nerves. (05 Mar 2000) |
| inhibitory-motor | <physiology> A term applied to certain nerve centers which govern or restrain subsidiary centers, from which motor impressions issue. Source: Websters Dictionary (01 Mar 1998) |
| inhibitory nerve | <anatomy, nerve> A nerve conveying impulses that diminish functional activity in a part. (05 Mar 2000) |
| inhibitory postsynaptic potential | The change in potential produced in the membrane of the next neuron when an impulse which has an inhibitory influence arrives at the synapse; it is a local change in the direction of hyperpolarization; the frequency of discharge of a given neuron is determined by the extent to which impulses that lead to excitatory postsynaptic potential's predominate over those that cause inhibitory postsynaptic potential's. (05 Mar 2000) |
| inhibitory synapse | A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell. The most common inhibitory neurotransmitter is GABA, this opens channels in the postsynaptic cell which tend to stabilise its resting potential, thus rendering it less likely to fire. See: excitatory synapse, presynaptic inhibition, postsynaptic inhibition. (18 Nov 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|