| LHNCBC | Lister Hill National Center for Biomedical Communication |
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| MJ | Machado-Joseph [disease]; marijuana; megajoule |
| MJAD | Machado-Joseph Azorean disease |
| MJD | Machado-Joseph disease; Mseleni joint disease |
| MJD | Machado Joseph Disease |
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| Lister, Joseph | <person> Lister's surgical achievements certainly place him as the figurehead of English medicine. Born into a studious Quaker family in Upton, England, where his father was a wealthy wine merchant and also a maker of optical instruments, Joseph was influenced into scientific problems. While a medical student, he was encouraged in research, and later published two articles, the first on the dilator and sphincter muscles of the iris (enlarge and diminish the size of the pupil) and the second, describing the involuntary muscles (erector pillores) of the skin which elevated the hairs (and cause "goose bumps"). After graduating from the non-sectarian University of London Medical School, (called the Godless College) he became interested in microscopic anatomy, physiology, the mechanism of inflammation, and intravascular clotting. Lister migrated to Edinburgh, to visit the famous Syme's Clinic, married Agnes, the daughter of James Syme, Professor of Surgery, and six years later became Chief of Surgery at Glasgow. He experienced friends and dissenters throughout his life. Deeply impressed by the high incidence of mortality after amputations (45%), he insisted on rigid cleanliness. These were the times that "laudable pus" was necessary to heal wounds. Lister was firmly convinced that pus (purulency) was not necessary, but was actually detrimental to healing. He tried various antiseptic solutions (zinc chloride, bichloride of mercury, sulfites) to sterilise wounds and finally settled on carbolic acid spray (1865). His patients' mortality dropped dramatically. Lister soaked his silk and catgut sutures in carbolic acid, and used the same solution when he cleansed and dressed wounds frequently. Joseph Lister was called to Edinburgh to follow his father-in-law, Syme as professor. He was the first physician to sit in the House of Lords (1897). Upon his death this peer of the surgical world was buried in Westminster Abbey alongside his wife, and the entire guild of surgeons realised that the British island had laid to rest her greatest surgeon. Lived: 1827-1912. (18 Nov 1997) |
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| Lister, Joseph Lord | <person> English surgeon, 1827-1912. See: Listerella, Listeria, listerism, Lister's dressing, Lister's method, Lister's tubercle. (05 Mar 2000) |
| Joseph Lister | <person> Lister's surgical achievements certainly place him as the figurehead of English medicine. Born into a studious Quaker family in Upton, England, where his father was a wealthy wine merchant and also a maker of optical instruments, Joseph was influenced into scientific problems. While a medical student, he was encouraged in research, and later published two articles, the first on the dilator and sphincter muscles of the iris (enlarge and diminish the size of the pupil) and the second, describing the involuntary muscles (erector pillores) of the skin which elevated the hairs (and cause "goose bumps"). After graduating from the non-sectarian University of London Medical School, (called the Godless College) he became interested in microscopic anatomy, physiology, the mechanism of inflammation, and intravascular clotting. Lister migrated to Edinburgh, to visit the famous Syme's Clinic, married Agnes, the daughter of James Syme, Professor of Surgery, and six years later became Chief of Surgery at Glasgow. He experienced friends and dissenters throughout his life. Deeply impressed by the high incidence of mortality after amputations (45%), he insisted on rigid cleanliness. These were the times that "laudable pus" was necessary to heal wounds. Lister was firmly convinced that pus (purulency) was not necessary, but was actually detrimental to healing. He tried various antiseptic solutions (zinc chloride, bichloride of mercury, sulfites) to sterilise wounds and finally settled on carbolic acid spray (1865). His patients' mortality dropped dramatically. Lister soaked his silk and catgut sutures in carbolic acid, and used the same solution when he cleansed and dressed wounds frequently. Joseph Lister was called to Edinburgh to follow his father-in-law, Syme as professor. He was the first physician to sit in the House of Lords (1897). Upon his death this peer of the surgical world was buried in Westminster Abbey alongside his wife, and the entire guild of surgeons realised that the British island had laid to rest her greatest surgeon. Lived: 1827-1912. (18 Nov 1997) |
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| lister | A spear armed with three or more prongs, for striking fish. Source: Websters Dictionary (01 Mar 1998) |
| Lister's dressing | The first type of antiseptic dressing, one of gauze impregnated with carbolic acid. (05 Mar 2000) |
| Lister's method | Antiseptic surgery, as first advocated by Lister in 1867; the operation was performed under a cloud of diluted carbolic acid spray, the instruments were dipped in a carbolic solution before use, and the wound was dressed with a thick layer of carbolised gauze; from this was developed the present practice of aseptic surgery. Synonym: listerism. (05 Mar 2000) |
| Lister's tubercle | dorsal tubercle of radius |
| Acosta, Joseph de | <person> Spanish Jesuit missionary, 1539-1600. See: Acosta's disease. (05 Mar 2000) |
| Arneth, Joseph | <person> German physician, 1873-1955. See: Arneth classification, Arneth count, Arneth formula, Arneth index, Arneth stages. (05 Mar 2000) |
| Aub, Joseph | <person> U.S. Physician, 1890-1973. See: Aub-DuBois table. (05 Mar 2000) |
| Babinski, Joseph | <person> French neurologist, 1857-1932. See: Babinski's phenomenon, Babinski's sign, Babinski reflex, Babinski's syndrome. (05 Mar 2000) |
| Beau, Joseph | <person> French physician, 1806-1865. See: Beau's lines. (05 Mar 2000) |
| Bertin, Exupere Joseph | <person> French anatomist, 1712-1781. See: Bertin's bones, Bertin's columns, Bertin's ligament, Bertin's ossicles. (05 Mar 2000) |
| Machado-Joseph | A rare form of hereditary ataxia, characterised by onset in early adult life of progressive, spinocerebellar and extrapyramidal disease with external ophthalmoplegia, rigidity dystonia symptoms, and, often, peripheral amyotrophy; found predominantly in people of Azorean ancestry; autosomal dominant inheritance. Synonym: Azorean disease, Portuguese-Azorean disease. Origin: Surnames of two families studied in major descriptions of the disease. (05 Mar 2000) |
| machado-joseph disease | A progressive degenerative disease of the central nervous system occurring in portuguese-azorean families, having a variety of forms and inherited as an autosomal dominant trait. There are four major types: type I: with pyramidal and extrapyramidal deficits; type II: with cerebellar, pyramidal and extrapyramidal deficits; type III: with cerebellar deficits and distal sensorimotor neuropathy; type IV: with parkinsonism and distal sensory neuropathy. It was originally reported in two portuguese-azorean families in massachusettes (machado), then in another portuguese family (thomas), and later in a third family in california (joseph, who settled there in 1845). It has been reported also in japanese families. (12 Dec 1998) |
| Pancoast, Joseph | <person> U.S. Surgeon, 1805-1882. See: Pancoast's suture. (05 Mar 2000) |
| Paneth, Joseph | <person> A Physiologist who held Chairs in the Universities of Breslau and Vienna. Paneth's Cells - "cellules etroites" of the mucosa of the small intestine. Lived: 1857-1890. B. Vienna, Oct 6th, 1857, d. Vienna, Jan 4th, 1890. (05 Dec 1998) |
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