| ¿µ¹® | pharmacology | ÇÑ±Û | ¾à¸®ÇÐ |
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| ¼³¸í | ¾àÀ» ´Ù·ç´Â ¸ðµç °ü·ÃºÐ¾ß¸¦ ¿¬±¸ÇÏ´Â Çй®. ¾àÀ̶õ ´Ü¼øÈ÷ ¾à±¹À̳ª, ȤÀº º´¿ø¿¡¼ ´Â °Í¸¸ÀÌ ¾Æ´Ñ, ¸ðµç ÈÇй°ÁúÀÌ ¾àÀÌ µÉ ¼öÀÖ´Ù. ¾à¸®ÇÐÀº ¾àÀÇ ¼ºÁú, ±â¿ø, ÀÎü¿¡ ´ëÇÑ È¿°ú µîÀ» ¿¬±¸ÇÏ´Â Çй®ÀÌ´Ù. ¾à¸®ÇÐÀº ¶ÇÇÑ ¿©·¯ °¡Áö °è¿·Î ³ª´µ¾îÁö¸ç, ƯÈ÷ ºÐÀھฮÇÐ(molecular pharmacology)´Â ºÐÀÚ¼öÁØ¿¡¼ ¾àÀÇ ÀÎü¿¡ ´ëÇÑ ÀÛ¿ëÀ» ¿¬±¸ÇϹǷνá, ¾àÈ¿´ÉÀÇ ±âÀüÀ» ¾Ë¾Æº¸·Á´Â Çй®ÀÌ´Ù. ±×¸®°í, ½ÇÁ¦·Î ÀÓ»ó¿¡¼ ¾²´Â ¾àÈ¿°ú¿¡ ´ëÇÑ ¿¬±¸¿Í °³°³Àο¡ ´ëÇÑ Â÷ÀÌ, ¾àÀ¸·Î ÀÎÇÑ ºÎÀÛ¿ëÀ» Àü¹®ÀûÀ¸·Î ¿¬±¸ÇÏ´Â ÀÓ»ó¾à¸®ÇÐÀÌ ÀÖ´Ù. |
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| ¿µ¹® | autonomic nervous system | ÇÑ±Û | ÀÚÀ²½Å°æ°è |
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| ¼³¸í | »ç¶÷ÀÇ ÀÇÁö¿Í °ü°è¾øÀÌ, ħÀ» È긮°Å³ª ¼Òȿ µî°ú °°Àº ½º½º·Î Á¶Á¤ÀÌ µÇ¾î ¿òÁ÷ÀÌ´Â ½Å°æ°èÀÌ¸ç ¿©±â¿¡´Â ´ÙÀ½°ú °°Àº µÎ °¡Áö°¡ ÀÖ´Ù. 1.±³°¨½Å°æ°è(sympathetic nervous system)-»ç¶÷ÀÌ À§Çè»óÅ¿¡ À̸£·¶À» °æ¿ì¿¡ ÈïºÐÀÌ µÇ´Â ÀÚÀ²½Å°æ°è. Áï ½É¹Ú¼öÀÇ Áõ°¡, ¼Òȱ⠿ÀÇ °¨¼Ò µîÀÇ ÀÏÀÌ À̰÷À» ÅëÇØ¼ ÀϾÙ. ±³°¨½Å°æÀÌ ÈïºÐµÇ¸é ±³°¨½Å°æÀÇ ¸»´Ü¿¡¼ epinephrine, norepinephrine µîÀÇ ¹°ÁúÀÌ ºÐºñµÇ°í À̰͵鿡 ÀÇÇØ¼ ¸»ÃÊÀå±â°¡ º¯È¸¦ ÀÏÀ¸Å²´Ù. ÇÏÁö¸¸ Àå±â¿¡ µû¶ó¼ epinephrineÀ̳ª norepinephrineÀÇ ¼ö¿ëü¸¦ °¡Áö°í ÀÖ¾î¼ ¿©·¯ °¡Áö ´Ù¸¥ Àå±âÀÇ ¹ÝÀÀÀ» º¼ ¼ö°¡ ÀÖ´Ù. ¼ö¿ëü´Â ´ÙÀ½°ú °°´Ù. -¾ËÆÄ¼ö¿ëü(alpha-receptor): ¸»ÃÊÇ÷°üÀÇ ¼öÃà, ±â°üÁöÀÇ ¼öÃà, µ¿°øÀÇ ±ÙÀ°ÀÇ ¼öÃà -º£Å¸1¼ö¿ëü(beta 1-receptor): ½ÉÀå¿¡ Á¸ÀçÇÏ´Â ¼ö¿ëü, ½ÉÀåÀ» »¡¸® ¶Ù°ÔÇÏ´Â ¿ªÇÒÀ» ÇÑ´Ù. -º£Å¸2¼ö¿ëü(beta 2-receptor): Ç÷°üÀÇ ÀÌ¿Ï, ±â°üÁöÀÇ ÀÌ¿Ï, Áï °¢ Àå±âµéÀº ±× Àå±â°¡ °¡Áö°í ÀÖ´Â ±³°¨½Å°æÀÇ ¼ö¿ëü¿¡ µû¶ó ±³°¨½Å°æÀÇ ÈïºÐ(±³°¨½Å°æ ¸»´Ü¿¡¼ÀÇ epinephrineÀÇ ºÐºñ)¿¡ ´ëÇÑ ¹ÝÀÀÀÌ ´Þ¶óÁø´Ù(¿¹-±³°¨½Å°æÀÌ ÈïºÐ½Ã¿¡ beta 1-¼ö¿ëü¸¦ °¡Áö°í ÀÖ´Â ½ÉÀåÀº »¡¸® ¶Ù°Ô µÈ´Ù. ±³°¨½Å°æ ÈïºÐ½Ã¿¡ µ¿°øÀÇ ±ÙÀ°ÀÌ ¼öÃàÇØ¼ µ¿°øÀÇ Å©±â°¡ Ä¿Áø´Ù) 2.ºÎ±³°¨½Å°æ°è(parasympathetic nervous system)-±³°¨½Å°æ°ú ¹Ý´ë·Î ÀÛ¿ëÇÑ´Ù. Áï »ç¶÷ÀÌ Á¹¸®°Å³ª ½¯ °æ¿ì¿¡ ÈïºÐÇÑ´Ù. ºÎ±³°¨½Å°æÀÌ ÈïºÐÇÒ ¶§¿¡´Â ½Å°æÀÇ ¸»´Ü¿¡¼ ¾Æ¼¼Ä¥Äݸ°ÀÇ ºÐºñ°¡ ÀϾ°í À̰ÍÀ¸·Î ÀÎÇØ¼ °¢ Àå±âÀÇ º¯È°¡ ÀϾÙ. |
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| ACCP | American College of Chest Physicians; American College of Clinical Pharmacology; American College of... |
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| AMSP | Association of Medical School Pharmacology |
| DPhc | Doctor of Pharmacology |
| ISBP | International Society for Biochemical Pharmacology |
| IUPHAR | International Union of Pharmacology |
| JAMA | Journal of the American Medical Association |
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| NEJM | New England Journal of Medicine |
| AD | Autonomic Dysreflexia |
| ANS | Autonomic Nervous System |
| AF | Autonomic failure |
| journal article | The predominant publication type for articles and other items indexed for nlm databases. (12 Dec 1998) |
|---|---|
| pharmacology | <study> The medical science that deals with the discovery, chemistry, effects, uses and manufacture of drugs. (09 Oct 1997) |
| pharmacology, clinical | The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans. (12 Dec 1998) |
| autonomic | <physiology> Self controlling, functionally independent. (02 Jan 1998) |
| autonomic agents | Agents affecting the function of, or mimicking the actions of, the autonomic nervous system and thereby having an effect on such processes as respiration, circulation, digestion, body temperature regulation, certain endocrine gland secretions, etc. (12 Dec 1998) |
| autonomic denervation | The removal or interruption of some part of the autonomic nervous system for therapeutic or research purposes. (12 Dec 1998) |
| autonomic disorder | Disorganization of autonomic processes. (05 Mar 2000) |
| autonomic epilepsy | Episodes of autonomic dysfunction presumably due to diencephalic irritation. Synonym: diencephalic epilepsy, vasomotor epilepsy, vasovagal epilepsy. (05 Mar 2000) |
| autonomic fibres, postganglionic | Nerve fibres which project from cell bodies of autonomic ganglia to synapses on target organs. (12 Dec 1998) |
| autonomic fibres, preganglionic | Nerve fibres which project from the central nervous system to autonomic ganglia. In the sympathetic division most preganglionic fibres originate with neurons in the intermediolateral column of the spinal cord, exit via ventral roots from upper thoracic through lower lumbar segments, and project to the paravertebral ganglia; there they either terminate in synapses or continue through the splanchnic nerves to the prevertebral ganglia. In the parasympathetic division the fibres originate in neurons of the brainstem and sacral spinal cord. In both divisions the principal transmitter is acetylcholine but peptide cotransmitters may also be released. (12 Dec 1998) |
| autonomic ganglia | Visceral ganglia. See: autonomic nervous system. (05 Mar 2000) |
| autonomic hyperreflexia | <physiology> An autonomic response that may include hypertension, sweating, bradycardia and severe headache. Autonomic hyperreflexia may occur secondary to an injury to the upper spinal cord, during cystoscopy or with distention of the bladder or colon. (02 Jan 1998) |
| autonomic imbalance | A lack of balance between sympathetic and parasympathetic nervous systems, especially in relation to the vasomotor disturbances. Synonym: vasomotor imbalance. (05 Mar 2000) |
| autonomic motor neuron | See: motor neuron. (05 Mar 2000) |
| autonomic motor neurons | (preganglionic neuron's), by contrast, innervate smooth muscle fibres or glands only by the intermediary of a second, peripheral, neuron (postganglionic or ganglionic m. Neuron) located in an autonomic ganglion. See: motor endplate, autonomic nervous system. Synonym: anterior horn cell, motoneuron. (05 Mar 2000) |
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