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"J Lipid Mediat Cell Signal"¿¡ ´ëÇÑ °Ë»ö °á°úÀÔ´Ï´Ù. °Ë»ö °á°ú º¸´Â µµÁß¿¡ Tab ۸¦ ´©¸£½Ã¸é °Ë»ö âÀÌ ¼±Åõ˴ϴÙ.
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¿µ¹® signal transduction ÇÑ±Û ½ÅÈ£Àü´Þ
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¿µ¹® lipid ÇÑ±Û ÁöÁú
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¿µ¹® muscle cell(=muscle fiber) ÇÑ±Û ±ÙÀ°¼¼Æ÷
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¿µ¹® white blood cell(WBC), leukocyte ÇÑ±Û ¹éÇ÷±¸
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  Ç÷¾×³»¿¡ °ñ¼ö±¸°è¼¼Æ÷¿Í ¸²ÇÁ°è¼¼Æ÷, ´ÜÇÙ±¸°è¼¼Æ÷¸¦ ¸ðµÎ ÅëÆ²¾î ¸»ÇÑ´Ù. ¹éÇ÷±¸ÀÇ Áõ°¡°¡ ÀÖÀ¸¸é ´ë°³ °¨¿°ÀÌ Àְųª, È¤Àº Å»¼öÇö»óÀÌ ÀÖÀ½À» ÀǹÌÇÑ´Ù. ¶ÇÇÑ Áö³ªÄ£ ¹éÇ÷±¸¼öÀÇ °¨¼Ò´Â ÀÎü³» ¸é¿ª±â´ÉÀÌ ¶³¾îÁ® ÀÖÀ½À» ÀǹÌÇϸç, ´Ù¸¥ Áúº´¿¡ ÀÇÇØ ³ªÅ¸³ª´Â ÀÌÂ÷ÀûÀΠÇö»óÀÌ ¾Æ´ÑÁö ²À Áø´ÜÀ» ¹Þ¾Æº¸¾Æ¾ß ÇÑ´Ù.
¿µ¹® mast cell ÇÑ±Û ºñ¸¸ ¼¼Æ÷
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  µ¿¹°ÀÇ °áÇÕ Á¶Á÷ °¡¿îµ¥ ³Î¸® ºÐÆ÷Çϴ ¼¼Æ÷. °áÇÕÁ¶Á÷°ú Á¡¸·Á¶Á÷ ³»¿¡ Àִ ȣ¿°±â¼º »ö¼Ò·Î ÀÌ¿°»ö¼º(metachromasia)À» ³ªÅ¸³»´Â °ú¸³À» °¡Áø ¹æÃßÇüÀÇ ¼¼Æ÷¿¡ ÀÛÀº µÕ±Ù ÇÙÀ» °¡Áø´Ù. ºñ¸¸¼¼Æ÷ÀǠǥ¸é¿¡´Â IgE¿¡ ´ëÇÑ ¼ö¿ëü°¡ Á¸ÀçÇϸç, ¼ö¿ëü¿¡ °áÇÕÇÑ IgE ºÐÀڵ鳢¸® ´Ù°¡ÀÇ Ç׿ø¿¡ ÀÇÇØ ¼­·Î ¿¬°áµÇ¸é ºñ¸¸¼¼Æ÷ °ú¸³Å»Ãâ ¹ÝÀÀÀÌ ÀϾ, È÷½ºÅ¸¹Î, ¼¼·ÎÅä´Ñ, ÇìÆÄ¸° µîÀÇ È­ÇÐÀü´Þ ¹°ÁúÀÌ ¹æÃâµÇ¾î, Áï½ÃÇü ¾Ë·¹¸£±â ¹ÝÀÀ µîÀÇ Áõ»óÀ» ÀÏÀ¸Å²´Ù. ÇǺÎ, À帷, Ç÷°ü ÁÖÀ§, Á¡¸· ÁÖº¯¿¡ ÀÖ´Ù.
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  • ¿µ¹®
    ÇѱÛ
  • lipid
    ÁöÁú
  • lipid granule
    Áö¹æ°ú¸³
  • lipid infiltration
    ÁöÁúħÀ±
  • lipid layer
    ÁöÁúÃþ
  • lipid pneumonia
    ÁöÁúÆó·Å
  • lipid proteinosis
    ÁöÁú´Ü¹éÁõ
  • lipid solubility
    ÁöÁú¿ëÇØµµ
  • lipid storage disease
    ÁöÁúÃàÀûº´
  • lipid-soluble
    Áö¿ë¼º-
  • analog signal
    ¾Æ³¯·Î±×½ÅÈ£
  • electric signal
    Àü±â½ÅÈ£
  • flow signal
    È帧½ÅÈ£, À¯µ¿½ÅÈ£
  • high signal
    °­ÇѽÅÈ£, °í½ÅÈ£
  • high signal intensity
    °í½ÅÈ£°­µµ
  • high velocity signal loss
    °í¼Ó½ÅÈ£¼Ò½Ç
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  • ¿µ¹®
    ÇѱÛ
  • lipid
    ÁöÁú
  • signal averaging
    ½ÅÈ£Æò±Õ
  • signal intensity
    ½ÅÈ£°­µµ
  • signal loss
    ½ÅÈ£¼Ò½Ç
  • signal-to-noise ratio
    ½ÅÈ£´ëÀâÀ½ºñ
  • signal
    ½ÅÈ£
  • low signal
    ¾àÇѽÅÈ£, Àú½ÅÈ£
  • signal symptom
    °æ°íÁõ»ó
  • signal transduction
    ½ÅÈ£Àü´Þ
  • signal void
    ¹«½ÅÈ£
  • sickle cell anemia
    ³´ÀûÇ÷±¸ºóÇ÷
  • cell
    ¼¼Æ÷
  • accessory cell
    º¸Á¶¼¼Æ÷, µ¡¼¼Æ÷
  • acinar cell
    »ù²Ê¸®¼¼Æ÷
  • amacrine cell
    ¹«Ãà»è¼¼Æ÷
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  • ¿µ¹®
    ÇѱÛ
  • lipid storage disease
    ÁöÁúÃàÀûº´
  • lipid granule
    Áö¹æ°ú¸³
  • lipid hypothesis
    ÁöÁú°¡¼³
  • lipid infiltration
    ÁöÁúħÀ±
  • lipid
    ÁöÁú
  • lipid-soluble
    Áö¿ë¼º-
  • lipid layer
    ÁöÁúÃþ
  • lipid pneumonia
    ÁöÁúÆó·Å
  • lipid proteinosis
    ÁöÁú´Ü¹éÁõ
  • lipid solubility
    ÁöÁú¿ëÇØµµ
  • analog signal
    ¾Æ³¯·Î±×½ÅÈ£
  • signal alteration
    ½ÅÈ£º¯°æ
  • signal amplitude
    ½ÅÈ£ÁøÆø
  • signal anxiety
    ½ÅÈ£ºÒ¾È
  • signal averaging
    ½ÅÈ£Æò±Õ
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  • ¿µ¹®
    ÇѱÛ
  • Dorfman-Chanarin syndrome = neutral lipid storage disease
    Áß¼ºÁö¹æÃàÀûÁõ
  • Lipid Research Clinic
    ÁöÁú¿¬±¸Áø·á¼Ò
  • Lipid bilayer
    Áö¹æÀÌÁßÃþ(ò·Û¸ì£ñìöµ)
  • free radical formation,lipid peroxidation
    ÀÚÀ¯ ·¡µðÄ® Çü¼º, ÁöÁú °ú»êÈ­(ò·òõ Φ߫ûù)
  • granule, lipid
    Áö¹æ°ú¸³
  • MR signal
    ÀÚ±â°ø¸í ½ÅÈ£
  • SNR (signal to noise ratio)
    ½ÅÈ£´ë ÀâÀ½ºñÀ²
  • analog signal
    ¾Æ³¯·Î±× ½ÅÈ£
  • free induction decay signal (FID)
    ÀÚÀ¯ À¯µµ ºØ±« ½ÅÈ£
  • high signal
    °í½ÅÈ£
  • high signal intensity
    °í½ÅÈ£ °­µµ
  • high velocity signal loss
    °í¼Óµµ ½ÅÈ£ ¼Ò½Ç
  • immunogenic signal
    ¸é¿ª¿ø½ÅÈ£
  • predictive value of control signal
    Á¦¾î<´ëÁ¶>½ÅÈ£ÀÇ ¿¹ÃøÄ¡
  • primary signal system
    ÀÏÂ÷½ÅÈ£°è(ìéó­ãáûÜ Í§).
¿¾ ´ëÇÑÀÇÇù 3 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • lipid cell tumor
    ÁöÁú¼¼Æ÷ Á¾¾ç(¡­á¬øà ðþåË)
  • blood lipid
    Ç÷¾×ÁöÁú(úìäûò·òõ).
  • fecal lipid
    ºÐº¯Áö¹æ
  • free radical formation,lipid peroxidation
    ÀÚÀ¯ ·¡µðÄ® Çü¼º, ÁöÁú °ú»êÈ­(ò·òõ Φ߫ûù)
  • granule, lipid
    Áö¹æ°ú¸³
  • lipid
    ÁöÁú(ò·òõ)
  • lipid
    ÁöÁú(ò·òõ).
  • lipid
    ÁöÁú(ò·òõ)
  • lipid A
    ÁöÁú A
  • lipid drop
    Áö¹æ¹æ¿ï
  • lipid droplet
    Áö¹æ¹æ¿ï
  • lipid hypothesis
    ÁöÁú°¡¼³
  • lipid infiltration
    ÁöÁúħÀ±(¡­öÕëÈ).
  • lipid keratopathy
    ÁöÁú°¢¸·º´Áõ
  • lipid matabolism
    Áö¹æ´ë»ç(ò·Û¸ÓÛÞó)
´ëÇÑÇØºÎÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • Lipid drop
    Áö¹æ¹æ¿ï
    [¿¾ ¿ë¾î] Áö¹æ¼ÒÀû
  • Lipid droplet
    Áö¹æ¹æ¿ï
    [¿¾ ¿ë¾î] Áö¹æ¼ÒÀû
  • Chief cell [Type I glomus cell]
    °ú¸³¼¼Æ÷
    [¿¾ ¿ë¾î] ÁÖ¼¼Æ÷(Á¦1Çü»ç±¸¼¼Æ÷)
  • Clear cell [Epinephrine cell]
    ¹àÀº¼¼Æ÷ [¿¡Çdz×ÇÁ¸°¼¼Æ÷]
    [¿¾ ¿ë¾î] ¸í¼¼Æ÷(¿¡Çdz×ÇÁ¸°ºÐºñ¼¼Æ÷)
  • Sustentacular cell [Sertoli cell]
    ¹öÆÀ¼¼Æ÷
    [¿¾ ¿ë¾î] ÁöÁÖ¼¼Æ÷
  • Beta cell [Insulin cell]
    º£Å¸¼¼Æ÷ [Àν´¸°¼¼Æ÷]
    [¿¾ ¿ë¾î] º£Å¸¼¼Æ÷
  • Secretory epithelial cell [Glandular cell]
    ºÐºñ»óÇǼ¼Æ÷ [»ù¼¼Æ÷]
    [¿¾ ¿ë¾î] ºÐºñ»óÇǼ¼Æ÷
  • Interstitial cell [Dark cell]
    »çÀÌÁú¼¼Æ÷
    [¿¾ ¿ë¾î] °£Áú¼¼Æ÷
  • Interstitial cell [Leydig`s cell]
    »çÀÌÁú¼¼Æ÷
    [¿¾ ¿ë¾î] °£Áú¼¼Æ÷
  • Bronchiolar cell [Clara cell]
    ¼¼±â°üÁö¼¼Æ÷
    [¿¾ ¿ë¾î] ºÐºñ¼¼Æ÷
  • Parafollicular cell [Calcitonin cell]
    ¼ÒÆ÷°ç¼¼Æ÷
    [¿¾ ¿ë¾î] ¼ÒÆ÷¹æ¼¼Æ÷
  • Neurolemmal cell [Schwann`s cell]
    ½Å°æÁý¼¼Æ÷
    [¿¾ ¿ë¾î] ½Å°æÃʼ¼Æ÷
  • Alpha cell [Glucagon cell]
    ¾ËÆÄ¼¼Æ÷ [±Û·çÄ«°ï¼¼Æ÷]
    [¿¾ ¿ë¾î] ¾ËÆÄ¼¼Æ÷
  • Dark cell [Norepinephrine cell]
    ¾îµÎ¿î¼¼Æ÷ [³ë¸£¿¡Çdz×ÇÁ¸°¼¼Æ÷]
    [¿¾ ¿ë¾î] ¾Ï¼¼Æ÷(³ë¸£¿¡Çdz×ÇÁ¸°ºÐºñ¼¼Æ÷)
  • Chief cell [Type I glomus cell]
    °ú¸³¼¼Æ÷
    [¿¾ ¿ë¾î] ÁÖ¼¼Æ÷
´ëÇѱâ»ýÃæÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 9 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • excretory cell
    ¹è¼³¼¼Æ÷
  • flame cell
    ºÒ²É¼¼Æ÷
  • G cell G
    ¼¼Æ÷
  • germ cell
    ¹è¼¼Æ÷
  • interstitial plasma cell pneumonia
    °£Áú¼ºÇüÁú¼¼Æ÷Æó¿°
  • nurse cell
    º¸¸ð¼¼Æ÷
  • renette cell
    ¹è¼³¼¼Æ÷
  • tegumental cell
    Ç¥ÇǼ¼Æ÷
  • vitelline cell
    ³­È²¼¼Æ÷
´ëÇÑ»ýÈ­ÇкÐÀÚ»ý¹°ÇÐȸ ¿ë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • dual signal hypothesis
    ÀÌÁß ½ÅÈ£¼³(ì£ñìãáûÜàã) (ÔÒ) synarchy
  • signal amplification
    ½ÅÈ£ÁõÆø(ãáûÜñòøë)
  • signal codons
    ½ÅÈ£(ãáûÜ)ÄÚµ·
  • signal hypothesis
    ½ÅÈ£¼³(ãáûÜàã)
  • signal peptide
    ½ÅÈ£(ãáûÜ)ÆéŸÀ̵å
  • signal peptidase
    ½ÅÈ£(ãáûÜ)ÆéƼµ¥À̽º
  • signal recognition protein
    ½ÅÈ£ÀÎÁö´Ü¹éÁú(ãáûÜìãò±Ó±ÛÜòõ)
  • signal sequence
    ½ÅÈ£¼­¿­(ãáûÜßíÖª)
  • signal-to-noise ratio
    ½ÅÈ£/ÀâÀ½ºñ(ãáûÜ/íÚëåÝï)
  • bare lipid membrane
    ¾Ë¸ö ÁöÁú¸·(ò·òõد)
  • bilayer lipid membrane
    ¾çÃþ ÁöÁú¸·(å»öµ ò·òõد)
  • bimolecular lamellar lipid membrane
    À̺ÐÀÚ(ì£ÝÂí­) ÆÇ»óÁöÁú¸·(÷ùßÒò·òõد)
  • bimolecular lipid membrane
    À̺ÐÀÚ ÁöÁú¸·(ì£ÝÂí­ò·òõد)
  • black lipid membrane
    Èæ ÁöÁú¸·(ýÙò·òõد)
  • C55 lipid carrier
    "C55 ÁöÁú¿î¹Ýü(ò·òõê¡Úæô÷),(ÔÒ) bactoprenol"
KI ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • lipid bound proton
    Áö¹æ°áÇվ缺ÀÚ
  • lipid-laden
    Áö¹æÀûÀç
  • analog signal
    ¾Æ³¯·Î±×½ÅÈ£
  • backscatter signal
    ÈĹæ»ê¶õ½ÅÈ£
  • clutter signal
    È¥¶õ½ÅÈ£
  • echo signal
    ¿¡ÄÚ½ÅÈ£
  • flow signal
    À¯µ¿½ÅÈ£
  • free induction decay signal
    ÀÚÀ¯À¯µµºØ±«½ÅÈ£
  • high signal
    °í½ÅÈ£
  • high signal intensity
    °í½ÅÈ£°­µµ
  • high velocity signal loss
    °í¼Óµµ½ÅÈ£¼Ò½Ç
  • low signal
    Àú½ÅÈ£
  • low signal intensity
    Àú½ÅÈ£°­µµ
  • MR signal
    ÀÚ±â°ø¸í½ÅÈ£
  • number of signal average [=NSA]
    ½ÅÈ£Æò±Õȸ¼ö
KMLE ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
MC mass casualties; mast cell; Master of Surgery [Lat. Magister Chirurgiae]; maximum concentration; Med...
LC Laennec cirrhosis; Langerhans cell; late clamped; large chromophobe; lecithin cholesterol acyltransf...
LCC lactose coliform count; left circumflex coronary (artery); left common carotid; left coronary cusp; ...
ACC accommodation; acetyl coenzyme A carboxylase; acinic cell carcinoma; acute care center; adenoid cyst...
GC ganglion cell; gas chromatography; general circulation; general closure; general condition; generali...
KMLE ÀÚµ¿ÃßÃâ ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
MLA 4'-Monophosphoryl lipid A
ALBP Adipocyte lipid binding protein
ABLC Amphotericin B Lipid Complex
BLM Bilayer lipid membrane
LA Lipid A
ÀÇÇÐ³í¹® ¾àÀÚ(Pubmed/Entrez) °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • JrId: 8510
    JournalTitle: Journal of lipid mediators and cell signalling.
    MedAbbr: J Lipid Mediat Cell Signal
    ISSN: 0929-7855
    ESSN:
    IsoAbbr:
    NlmId: 9430888
°æºÏ´ë Ä¡°ú´ëÇÐ ±¸°­³»°ú ±³½Ç »çÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
    ¼³¸í
  • lipid bilayer
    Áö¹æÁú Ãþ
    ¼¼Æ÷¸·Àº ÁöÁú ÀÌÁß ÃþÀ̶ó Çϸç, ÀÌ Áö¹æÁú ÃþÀº ÁÖ·Î ÀÎ ÁöÁú¿¡ ÀÇÇØ ±¸¼ºµÇ¾î ÀÖ´Ù. ÀÎ ÁöÁúÀº Ä£¼ö¼º°ú ¼Ò¼ö¼º ºÎÀ§·Î ±¸¼ºµÇ¾î ¼¼Æ÷¸·ÀÇ ¹°Áú À̵¿¿¡ ¿µÇâÀ» ³¢Ä£´Ù. ¶Ç Áö¹æÁú ÃþÀÇ ÄÝ·¹½ºÅ×·ÑÀº ÀÌ ÃþÀÇ ¾ÈÁ¤È­¸¦ µ½´Â´Ù.
  • lipid metabolism
    ÁöÁú ´ë»ç
    °£¿¡¼­ ÈçÈ÷ ÀϾ¸ç Áö¹æ»êÀÇ º£Å¸-»êÈ­ ¹× ¾Æ¼¼Æ® ¾Æ¼¼Å×ÀÌÆ® Çü¼º, ´ç ÁöÁú »ý¼º, ÄÝ·¹½ºÅ×·Ñ ¹× ÀÎ ÁöÁú Çü¼º, ´ç°ú ´Ü¹éÁú·ÎºÎÅÍ Áö¹æÀÇ Àüȯ µîÀÌ °¡Àå ´ëÇ¥ÀûÀÌ´Ù.
  • lipid proteinosis
    ÁöÁú ´Ü¹éÁõ
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COOH-terminal signal transamidase <enzyme> Present in the endoplasmic reticulum; catalyses concomitant cleavage of the signal peptide of nascent proteins destined to be processed to a glycosylphosphatidylinositol (gpi) and addition of the gpi anchor
Registry number: EC 2.3.2.-
Synonym: cooh-ts-transamidase, gpi transamidase, gpti transamidase
(26 Jun 1999)
signal 1. Noticeable; distinguished from what is ordinary; eminent; remarkable; memorable; as, a signal exploit; a signal service; a signal act of benevolence. "As signal now in low, dejected state As erst in highest, behold him where he lies." (Milton)
2. Of or pertaining to signals, or the use of signals in conveying information; as, a signal flag or officer. The signal service, a bureau of the government (in the United States connected with the War Department) organised to collect from the whole country simultaneous raports of local meteorological conditions, upon comparison of which at the central office, predictions concerning the weather are telegraphed to various sections, where they are made known by signals publicly displayed. Signal station, the place where a signal is displayed; specifically, an observation office of the signal service.
Synonym: Eminent, remarkable, memorable, extraordinary, notable, conspicuous.
Origin: From signal, n., cf. F. Signale.
Source: Websters Dictionary
(01 Mar 1998)
signal detection (psychology) A theory of psychophysics which characterises not only the acuity of an individual's discrimination but also the psychological factors that bias his judgment.
(12 Dec 1998)
signal node A firm supraclavicular lymph node, especially on the left side, sufficiently enlarged that it is palpable from the cutaneous surface; such a lymph node is so termed because it may be the first recognised presumptive evidence of a malignant neoplasm in one of the viscera. A signal node that is known to contain a metastasis from a malignant neoplasm is sometimes designated by an old eponym, Troisier's ganglion.
Synonym: jugular gland, Virchow's node.
(05 Mar 2000)
signal peptidase A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum.
See: signal recognition particle.
(18 Nov 1997)
signal peptidase complex A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum.
See: signal recognition particle.
(18 Nov 1997)
signal peptide A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum.
See: signal recognition particle.
(18 Nov 1997)
signal peptide p25-subunit IV cytochrome oxidase <chemical> Similar in action to melittin
Synonym: p25 presequence peptide-cytochrome oxidase, pre-ctox p25
(26 Jun 1999)
signal peptides Additional polypeptide sequence of 25 to 30 residues at the amino-terminal or carboxy-terminal end of proteins. The signal sequence signals the cellular fate or destination of a newly synthesised protein directing it to its ultimate destination in the cell. These leaders are recognised by the signal recognition particle and bound by specific receptor sites on the outer surface of the endoplasmic reticulum. They are then transported into the cisterna of the endoplasmic reticulum and from there directed to their ultimate destination in the cell. In prokaryotes, the signal peptides attach to the plasma membrane. These signal sequences are ultimately removed by specific peptidases.
(12 Dec 1998)
signal processing, computer-assisted Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.
(12 Dec 1998)
signal recognition particle A complex between a 7S RNA and six proteins. SRP binds to the nascent polypeptide chain of eukaryotic proteins with a signal sequence and halts further translation until the ribosome becomes associated with the rough endoplasmic reticulum. One of the SRP proteins (srp54) binds GTP and in association with 7SRNA and srp19 has GTPase activity.
(18 Nov 1997)
signal recognition particle receptor Receptor for the signal recognition particle (SRP) found in the membrane of the endoplasmic reticulum. Also called docking protein. Heterodimeric, both protomers having GTP binding capacity, though dissimilar binding sites. Not until the complex of SRP, ribosome, message and nascent polypeptide chain binds to the SRP receptor is the block to further chain elongation released and concurrently the SRP is released, leaving the ribosome attached to the endoplasmic reticulum membrane. Cotranslational transport of the polypeptide delivers it into the lumen of the ER.
(18 Nov 1997)
signal response coupling The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors.
(18 Nov 1997)
signal sequence A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum.
See: signal recognition particle.
(18 Nov 1997)
signal-to-noise ratio <microscopy> Also sometimes used as an abbreviation for serial number, can be somewhat confusing in the case of electronic equipment.
(05 Aug 1998)
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