| MIg | malaria immunoglobulin; measles immunoglobulin; membrane immunoglobulin |
|---|---|
| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
| FAB classification | French, American, British classification |
| FAB | fast atom bombardment; formalin ammonium bromide; fragment, antigen-binding [of immunoglobulins]; Fr... |
| Fab | fragment, antigen-binding [of immunoglobulins] |
| FAB | Fast Atom Bombardment |
|---|---|
| FAB-MS | Fast Atom Bombardment Mass Spectrometry |
| FAB MS | Fast Atom Bombardment Mass Spectroscopy |
| F 1+2 | fragments 1+2 |
| FAB | French American British |
| Okazaki fragments | Short fragments of newly synthesised DNA strands produced during DNA replication. All the known DNA polymerases can only synthesis DNA in one direction, the 5' to 3' direction. However as the strands separate, replication forks will be moving along one parental strand in the 3' to 5' direction and 5' to 3' on the other parental strand. On the former, the leading strand, DNA can be synthesised continuously in the 5' to 3' direction. On the other, the lagging strand, DNA synthesis can only occur when a stretch of single stranded DNA has been exposed and proceeds in the direction opposite to the movement of the replication fork (still 5' to 3). It is thus discontinuous and the series of fragments are then covalently linked by ligases to give a continuous strand. Such fragments were first observed by Okazaki using pulse labelling with radioactive thymidine. In eukaryotes, Okazaki fragments are typically a few hundred nucleotides long, whereas in prokaryotes they may contain several thousands of nucleotides. (18 Nov 1997) |
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| immunoglobulins, fab | Antigen-binding fragments composed of one entire light chain and about half of one of the heavy chains, linked to each other by disulfide bonds. Fab contains the antigen binding site which is part of the variable region of the immunoglobulin molecule. (12 Dec 1998) |
| Fab | <immunology> Fragment of immunoglobulin prepared by papain treatment. Fab fragments (45 kD) consist of one light chain linked through a disulphide bond to a portion of the heavy chain and contain one antigen binding site. They can be considered as univalent antibodies. (18 Nov 1997) |
| FAB classification | <haematology> The classification of acute myeloid leukaemia on the basis of bone marrow and peripheral blood features. M0: Acute myeloid leukaemia with minimal evidence of myeloid differentiation. M1: Acute myeloblastic leukaemia. M2: Acute myeloblastic leukaemia with differentiation. M3: Acute promyelocytic leukaemia. M4: Acute myelomonocytic leukaemia. M5: Acute monocytic leukaemia. M6: Acute erythroleukaemia. M7: Acute megakaryocytic leukaemia. Acronym: FAB (07 Apr 1998) |
| Fab fragment | The antigen-binding fragment of an immunoglobulin molecule, consisting of both a light chain and part of a heavy chain. Synonym: Fab piece. (05 Mar 2000) |
| Fab piece | The antigen-binding fragment of an immunoglobulin molecule, consisting of both a light chain and part of a heavy chain. Synonym: Fab piece. (05 Mar 2000) |
| anti-D immunoglobulin | rHo(D) immune globulin |
| rabies immunoglobulin | rabies immune globulin (human) |
| genes, immunoglobulin | Genes encoding the light and heavy chain segments of immunoglobulins. Light chain gene segments are symbolised l-v (variable), j (joining) and c (constant); ig heavy chain segments have, in addition, a diversity (d) gene. Each segment codes for certain amino acids, and each has a different nucleotide sequence; the genes are assembled by a remarkable shuffling of the segments during b lymphocyte maturation. (12 Dec 1998) |
| receptors, polymeric immunoglobulin | Specialised fc receptors (receptors, fc) for polymeric immunoglobulins, which mediate transcytosis of polymeric IgA and IgM into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IgA, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (secretory component) that is bound to IgA is proteolytically cleaved from its transmembrane tail. (12 Dec 1998) |
| measles immunoglobulin | measles immune globulin (human) |
| cellular immunodeficiency with abnormal immunoglobulin synthesis | An ill-defined group of sporadic disorders of unknown cause, occurring in both males and females and associated with recurrent bacterial, fungal, protozoal, and viral infections; there is thymic hypoplasia with depressed cellular (T-lymphocyte) immunity combined with defective humoral (B-lymphocyte) immunity, although immunoglobulin levels may be normal. Synonym: Nezelof syndrome, Nezelof type of thymic alymphoplasia. (05 Mar 2000) |
| Rho(D) immunoglobulin | rHo(D) immune globulin |
| chickenpox immunoglobulin | chickenpox immune globulin (human) |
| pertussis immunoglobulin | A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically. Synonym: pertussis immunoglobulin. (05 Mar 2000) |
Synonyms : Fab Immunoglobulin Fragments, Immunoglobulin Fab Fragment, Immunoglobulins, Fab, Fab Fragment Immunoglobulins, Fab Fragment, Immunoglobulin, Fab Fragments, Immunoglobulin, Fragment Immunoglobulins, Fab, Immunoglobulin Fragments, Fab
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