| ¿µ¹® | diabetic nephropathy | ÇÑ±Û | ´ç´¢º´ÄáÆÏº´Áõ |
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| AAN | AIDS-associated nephropathy; alpha-amino nitrogen; American Academy of Neurology; American Academy o... |
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| Ig | Immuno-globulin IgA; Immuno-globulin A; (27)(30)60(100) - (170)(80)(250)380 mg/dL |
| IgM¥áHBc | IgM Antibody against Hepatitis B core Antigen |
| IgM | immunoglobulin M |
| MGN | Membranous Glomerulo-Nephritis(Nephropathy) |
| IgM anti-HBc | IgM antibody to hepatitis B core antigen |
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| IgM RF | IgM rheumatoid factor |
| S-IgM | secretory IgM |
| IgM | Immunoglobulin M |
| IgM | Immunoglobulin G and M |
| IgM nephropathy | <nephrology, pathology> Inflammation of the kidney glomerulus (blood filtering portion of the kidney) due to the abnormal deposition of IgM antibody in the mesangium layer of the glomerular capillary. A form of glomerulonephritis that appears to be caused by an abnormal immune response. This disorder generally manifests as nephrotic syndrome. Symptoms include swelling, dark urine, weight gain, hypertension, anorexia and bloody urine. Acronym: MPGN (05 Jan 1998) |
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| IgM | <immunology> An immunoglobulin M molecule (970 kD) is built up from five immunoglobulin G type monomers joined together, with the assistance of J chains, to form a cyclic pentamer. Immunoglobulin M binds complement and a single molecule bound to a cell surface can lyse that cell. Immunoglobulin M is usually produced first in an immune response before immunoglobulin G. The human red cell isoantibodies are immunoglobulin M antibodies. Heavy chain (mu chain) is rather larger than the heavy chains of other immunoglobulins. (30 Mar 1998) |
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| IgM antibody capture ELISA | Developed to impart significant improvement in assay specificity to indirect ELISA procedures for IgM isotype antibodies. Solid-phase support (usually microtitre plate wells) are coated with anti-human IgM antibodies capable of binding all IgM isotype antibodies present in the specimen. Reagent antigen is then added, followed by enzyme-labelled antigen-specific antibodies. If IgM antibodies specific for the antigen in question are present, the "sandwich" complex will result in enzymatic colour-change proportional to the concentration of IgM-specific antibody present. This technique appears to be the method of choice in many highly specific and more sensitive assays for IgM infectious disease antibodies. Acronym: MAC ELISA (05 Mar 2000) |
| immunodeficiency with elevated IgM | Immunodeficiency with reduced IgG and IgA-bearing cells; there is recurrent pyogenic infection; X-linked in some families. (05 Mar 2000) |
| aids-associated nephropathy | Renal syndrome in human immunodeficiency virus-infected patients characterised by nephrotic syndrome, severe proteinuria, focal and segmental glomerulosclerosis with distinctive tubular and interstitial changes, enlarged kidneys, and peculiar tubuloreticular structures. The syndrome is distinct from heroin-associated nephropathy as well as other forms of kidney disease seen in HIV-infected patients. (12 Dec 1998) |
| analgesic nephropathy | <nephrology, pathology> A form of kidney damage which can occur from the overexposure to certain analgesics (for example acetaminophen, salicylates and non-steroidal anti-inflammatory agents). In most cases analgesic use is excessive in dosing or chronicity of use. Complications include acute renal failure. See: interstitial nephritis. Origin: Gr. Pathos = disease (27 Sep 1997) |
| balkan nephropathy | A tubulointerstitial disease of unknown aetiology occurring in a limited geographic area including adjacent regions of romania, bulgaria, and yugoslavia. (12 Dec 1998) |
| reflux nephropathy | <nephrology> A condition where the chronic backup of urine into a kidney results in kidney damage. Urine is forced out of the bladder and back toward kidney. This condition occurs most commonly in children who have congenital abnormalities of the urinary tract. Symptoms include back pain, flank, pain, abdominal pain, urinary frequency or urgency and blood in the urine. Other symptoms include nausea, fever and chills, most often indicating a kidney infection has occurred. Diagnosis is frequently confirmed by voiding cystourethrogram. Surgery is often required to correct the reflux of urine. Origin: Gr. Pathos = disease (27 Sep 1997) |
| membranous nephropathy | <pathology> A kidney disease that occurs due to inflammation of the kidney glomerulus and its basement membrane. The exact cause is unknown but it appears to be related to the deposition of immune complexes in the basement membrane leading to thickening of the capillary walls. This disorder is a common cause of nephrotic syndrome an is usually how the disease manifests. Risk factors include primary renal disease, malaria, hepatitis B, lupus, syphilis, cancers and non-Hodgkin's lymphomas. Risks also include exposure to some medications such as gold compounds and penicillamine. Mercury, trimethadione and some skin-lightening creams have also been implicated. Treatment includes systemic corticosteroids and immunosuppressive agents. (26 Mar 1998) |
| hereditary deafness and nephropathy | <nephrology, pathology> An inherited disorder involving damage to the kidneys, haematuria and hearing loss. In some individuals vision may also be affected. This genetic disease is uncommon. Symptoms include loss of hearing, abnormal colour to urine, swelling, cough and decline in vision. Inheritance: sex-linked autosomal dominant. Incidence: 1 in 50,000. Origin: Gr. Pathos = disease (27 Sep 1997) |
| hypokalaemic nephropathy | Vacuolation of the epithelial cytoplasm of renal convoluted tubules in patients seriously depleted of potassium; vacuoles do not contain fat or glycogen, concentrating ability is impaired, polyuria and polydipsia are common, and pyelonephritis may develop. Synonym: vacuolar nephrosis. (05 Mar 2000) |
| nephropathy | <nephrology, urology> Any disease of the kidneys. Origin: Gr. Pathos = disease (18 Nov 1997) |
| Danubian endemic familial nephropathy | A tubulointerstitial disease of unknown aetiology occurring in a limited geographic area including adjacent regions of romania, bulgaria, and yugoslavia. (12 Dec 1998) |
| diabetic nephropathy | <nephrology, pathology> Kidney disease and resultant kidney function impairment due to the long standing effects of diabetes on the microvasculature (glomerulus) of the kidney. Features include increased urine protein and declining kidney function. Severe diabetic nephropathy can lead to kidney failure and end-stage renal disease. Origin: Gr. Pathos = disease (27 Sep 1997) |
| IgA nephropathy | <nephrology, pathology> This is a form of glomerulonephritis that results from the deposition of circulating IgA antibody in the kidney tissues. Inflammation of the glomerulus (glomerulonephritis) is the result. This condition may present as acute glomerulonephritis, chronic glomerulonephritis or rapidly progressive glomerulonephritis. Berger's is usually detected in an individual with one or two bouts of bloody urine (usually begins during or soon after a respiratory infection) and no other symptoms of renal disease. Only rarely, will Berger's disease permanently affect kidney function and progress to chronic renal failure. This renal disorder more commonly affects males in the 16-40 age group. Origin: Gr. Pathos = disease (27 Sep 1997) |
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