| IMI | Imipenem |
|---|---|
| IPM | Imipenem |
| IPM/CS | Imipenem/Cilastatin |
| I/C | Imipenem/cilastatin |
| IPM/CS | Imipenem/cilastatin sodium |
| imipenem | <chemical> 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7- oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid. Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with cilastatin, a renal dipeptidase inhibitor. Pharmacological action: thienamycins. Chemical name: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5alpha,6alpha(R*)))- (12 Dec 1998) |
|---|
Synonyms : Imipenem, Anhydrous, MK-0787, MK0787, Anhydrous Imipenem, MK 0787, N Formimidoylthienamycin
| imipenem |
[USP] a broad-spectrum antibiotic of the carbapenem group, having activity against a wide range of gram-positive and gram-negative organisms. Because it is hydrolyzed by a dipeptidase occurring in the proximal renal tubule, it is administered with the dipeptidase inhibitor cilastatin sodium.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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