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CGRP Calcitonin Gene Related Peptide(Protein)
CGRPs Calcitonin Gene-Related Products
MEN Multiple Endocrine Neoplasia
  ; AD Trait
  1. MEN Type I(= Wermer Syndro...
CALC calcitonin
CALCR calcitonin receptor
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CGRP calcitonin-calcitonin gene-related peptide
CGRP AM/calcitonin gene-related peptide
alpha-CGRP Alpha calcitonin gene-related peptide
CT Calcitonin
CRLR Calcitonin Receptor-Like Receptor
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gastric hypersecretion Excessive formation of gastric juice, especially the acid component.
(05 Mar 2000)
hypersecretion <physiology> Excessive secretion.
(18 Nov 1997)
hypersecretion glaucoma Glaucoma caused by excessive formation of the aqueous humor.
(05 Mar 2000)
calcitonin <protein> A polypeptide hormone produced by C cells of the thyroid that causes a reduction of calcium ions in the blood.
(18 Nov 1997)
calcitonin gene-related peptide <protein> A second product transcribed from the calcitonin gene. Calcitonin gene related peptide is found in a number of tissues including nervous tissue. It is a vasodilator that may participate in the cutaneous triple response.
It is a neuropeptide of 37 amino acids with structural homology to salmon calcitonin. Co-localises with substance P in neurons. It occurs as a result of alternative processing of mRNA from the calcitonin gene.
The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.
Intracerebral administration leads to a rise in noradrenergic sympathetic outflow, a rise in blood pressure and a fall in gastric secretion.
Acronym: CGRP
(05 May 2002)
receptors, calcitonin Cell surface proteins that bind calcitonin and trigger intracellular changes which influence the behaviour of cells. Calcitonin receptors outside the nervous system mediate the role of calcitonin in calcium homeostasis. The role of calcitonin receptors in the brain is not well understood.
(12 Dec 1998)
receptors, calcitonin gene-related peptide Cell surface proteins that bind calcitonin gene-related peptide (cgrp) with high affinity and trigger intracellular changes which influence the behaviour of cells. Cgrp receptors are present in both the central nervous system and the periphery and are not the same as calcitonin receptors.
(12 Dec 1998)
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