| ¿µ¹® | carcinoma in situ | ÇÑ±Û | »óÇdz»¾ÏÁ¾ |
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| FISH | Fluorescence In Situ Hybridization |
|---|---|
| CISH | competitive in situ hybridization |
| FISH | fluorescence in situ hybridization |
| FLASH | fast low angle shot; fluorescence in situ hybridization |
| ISH | icteric serum hepatitis; in situ hybridization; internal self helper; International Society of Hemat... |
| FISH | Filter In Situ Hybridization |
|---|---|
| FISH | Fluorescence In Situ Hybridization |
| GISH | Genomic in situ hybridization |
| ISH | In situ hybridization histochemistry |
| I-FISH | Interphase fluorescence in situ hybridization |
| in situ hybridization | <molecular biology> The use of a DNA or RNA probe to detect the complementary DNA sequence. (12 Dec 1998) |
|---|---|
| in situ nucleic acid hybridization | <molecular biology> The use of a DNA or RNA probe to detect the complementary DNA sequence. (12 Dec 1998) |
| fluorescence in situ hybridization | <molecular biology, technique> A type of in situ hybridization in which target sequences are stained with fluorescent dye so their location and size can be determined using fluorescence microscopy. This staining is sufficiently distinct that the hybridization signal can be seen both in metaphase spreads and in interphase nuclei. Acronym: FISH (25 Jun 1999) |
| fluorescent in situ hybridization | See FISH. (12 Dec 1998) |
| adenocarcinoma in situ | A noninvasive abnormal proliferation of glands believed to precede the appearance of invasive adenocarcinoma; reported in the endometrium, large intestine, cervix, and other sites. (05 Mar 2000) |
| carcinoma in situ | Cancer that involves only the cells in which it began and has not spread to other tissues. Lobular carcinoma in situ is found in the lobules of the breast. Ductal carcinoma in situ (also called intraductal carcinoma) arises in the ducts. (16 Dec 1997) |
| malignant melanoma in situ | A melanoma limited to the epidermis and composed of nests of atypical melanocytes and scattered single cells extending into the upper epidermis; local excision is curative although the lesion, if untreated, may soon invade the dermis. Malignant lentigo may be considered a slowly progressive type of malignant melanoma in situ. (05 Mar 2000) |
| ductal carcinoma in situ | <oncology, tumour> A cancer inside the ducts of breast that has not grown through the wall of the duct into the surrounding tissues. Sometimes referred to as a precancer. Good prognosis is involved with in situ cancers. (09 Oct 1997) |
| in situ | In the natural or normal place, confined to the site of origin without invasion of neighbouring tissues. (18 Nov 1997) |
| in situ hybridisation | <molecular biology, technique> Use of a DNA or RNA probe todetect the presence of the complementaryDNA sequence in cloned bacterial or cultured eukaryotic cells.Also used for locating geneson chromosomes. The process is: Prepare microscope slide with cells in metaphase of mitosis, Treat slide with a weak base. Thus denaturing the DNA. Pour radioactively labelled probe onto the slide. Expose slide to photographic emulsion for a few days or weeks. Develop emulsion. (13 Oct 1997) |
| lobular carcinoma in situ | <tumour> Carcinoma of the breast in which small tumour cells fill preexisting acini within lobules, without invading the surrounding stroma. Synonym: lobular carcinoma in situ, lobular neoplasia. (05 Mar 2000) |
| cell hybridization | Fusion of two or more dissimilar cells, leading to formation of a synkaryon. (05 Mar 2000) |
| cross hybridization | Annealing of a DNA probe to an imperfectly matching DNA molecule. (05 Mar 2000) |
| protein hybridization | The formation of a protein consisting of two or more polypeptide chains from separate and different polypeptide chains. (12 Dec 1998) |
| hybridization | <molecular biology> The process of joining two complementary strands of DNA or one each of DNA and RNA to form a double-stranded molecule. Technique in which single stranded nucleic acids are allowed to interact so that complexes or hybrids, are formed by molecules with sufficiently similar, complementary sequences. By this means the degree of sequence identity can be assessed and specific sequences detected. The hybridisation can be carried out in solution or with one component immobilised on a gel or, most commonly, nitrocellulose paper. Hybrids are detected by various means: visualisation in the electron microscope, by radioactively labelling one component and removing noncomplexed DNA or by washing or digestion with an enzyme that attacks single stranded nucleic acids and finally estimating the radioactivity bound. Hybridisations are done in all combinations: DNA DNA (DNA can be rendered single stranded by heat denaturation), DNA RNA or RNA RNA. In situ hybridisations involve hybridising a labelled nucleic acid (often labelled with a fluorescent dye) to suitably prepared cells or histological sections. This is used particularly to look for specific transcription or localisation of genes to specific chromosomes (FISH analysis). <zoology> The mating of individuals from different species or sub-species. (13 Oct 1997) |
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