| WH | well hydrated; Werdnig-Hoffmann [syndrome]; whole homogenate; wound healing |
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| WHD | Werdnig-Hoffmann disease |
| WHS | Werdnig-Hoffmann syndrome; Wolf-Hirschhorn syndrome |
| H reflex | Hoffmann reflex |
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| H | Hoffmann |
| werdnig-hoffmann disease | A recessively inherited acute infantile form of motor neuropathy with proximal muscle wasting particularly of the upper extremities. The chronic childhood form may be an arrested werdnig-hoffmann disorder. (12 Dec 1998) |
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| Werdnig-Hoffmann muscular atrophy | Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised. Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
| Hoffmann, Freidrich | <person> German physician, 1660-1742. Professor of Anatomy and Surgery at Halle, noted for clinical observations of a variety of infectious diseases. (05 Mar 2000) |
| Hoffmann, Johann | <person> German neurologist, 1857-1919. See: Hoffmann's muscular atrophy, Hoffmann's phenomenon, Hoffmann's reflex, Hoffmann's sign, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
| Hoffmann, Moritz | <person> German anatomist, 1622-1698. See: Hoffmann's duct. (05 Mar 2000) |
| Hoffmann's duct | The excretory duct of the pancreas that extends through the gland from tail to head where it empties into the duodenum at the greater duodenal papilla. Synonym: ductus pancreaticus, Hoffmann's duct, Wirsung's canal, Wirsung's duct. (05 Mar 2000) |
| Hoffmann's muscular atrophy | Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised. Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
| Hoffmann's phenomenon | Excessive irritability of the sensory nerves to electrical or mechanical stimuli in tetany. (05 Mar 2000) |
| Hoffmann's reflex | <clinical sign> In latent tetany mild mechanical stimulation of the trigeminal nerve causes severe pain, flexion of the terminal phalanx of the thumb and of the second and third phalanges of one or more of the fingers when the volar surface of the terminal phalanx of the fingers is flicked. Synonym: digital reflex, Hoffmann's reflex, snapping reflex. (05 Mar 2000) |
| Hoffmann's sign | <clinical sign> In latent tetany mild mechanical stimulation of the trigeminal nerve causes severe pain, flexion of the terminal phalanx of the thumb and of the second and third phalanges of one or more of the fingers when the volar surface of the terminal phalanx of the fingers is flicked. Synonym: digital reflex, Hoffmann's reflex, snapping reflex. (05 Mar 2000) |
| Frei-Hoffmann reaction | <investigation> A clinical test where dead disease-causing microbes are injected into the skin to see if this causes a skin reaction. It indicates whether the patient is infected with the the injected microbe and is not used commonly. (07 Apr 1998) |
| Hoffmann's s. |
1. see under phenomenon. 2. in hemiplegia, a sudden nipping of the nail of the index, middle, or ring finger will produce flexion of the terminal phalanx of the thumb and of the second and third phalanges of some other finger; called also digital reflex and Hoffmann's reflex.
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