| COS | cheiro-oral syndrome; chief of staff; Clinical Orthopaedic Society; clinically observed seizures |
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| COS | Carbonyl sulfide |
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| COS | Childhood-onset schizophrenia |
| cos | cohesive end |
| cos | cohesive end site |
| Hippocrates of Cos | Greek physician, called the "Father of Medicine," circa 460-377 B.C. See: hippocratic facies, hippocratic fingers, hippocratic nails, school, succussion. (05 Mar 2000) |
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| hippocrates | A famous Greek physician and medical writer, born in Cos, about 460 B. C. Hippocrates' sleeve, a conical strainer, made by stitching together two adjacent sides of a square piece of cloth, especially. Flannel of linen. Source: Websters Dictionary (01 Mar 1998) |
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| COS cell | <cell culture> A cell line derived from the african green monkey and used for transfection and cloning. The cells are simian fibroblasts (CV 1 cells) transformed by SV40 that is deficient in the origin of replication region. They express large T antigen constitutively and if transfected with a vector containing a normal SV40 origin have all the other early viral genes necessary to generate multiple copies of the vector and thus to give very high levels of expression. (04 Jul 1999) |
| cos site | <molecular biology> A 12-nucleotide bases-long segment of single stranded DNA that exists at both ends of the bacteriophage lambda's double-stranded genome. The two cos sites at the ends of the genome are complementary to one another so that the genome can become circular once the virus has infected a host bacterium. The circular genome can then be duplicated continuously until there are many repeats of it strung together, the cos sites show the virus where to cut them apart right before they are packaged into individual capsids as new progeny viruses ready to infect more host cells. (10 Nov 1998) |
| Hippocrates of Cos |
the Father of Medicine, c. 460c. 375 B.C., a student and teacher, not founder, of the medical school on Cos. According to Plato and Aristotle, Hippocrates was a great physician. None of the works in the Hippocratic corpus can be surely ascribed to Hippocrates. His anatomy was vague: he knew only bones in detail, not being sure of the organs, muscles, nerves, tendons, or blood vessels. Hippocrates' physiology was based on humoralism; his diagnosis was directed toward general pathology; his prognosis, to foretell the stages, duration, and end of disease. Hippocrates closely observed fevers, skin, the tongue, eyes, sweat, urine, and feces. Malarial and pulmonary diseases, common in the ancient Mediterranean, provided Hippocrates with ample evidence of humors—hemorrhagic blood, black and yellow bile from fits of vomiting in remittent malaria, and phlegm in mucus and expectoration. Hippocrates' therapy was to restore the humoral equilibrium: rid the body of excess humors and replace the deficient humors. He relied on the healing power of nature and recommended diet and moderate exercise, but rejected drugs.
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