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HUR hydroxyurea
HURA health in underserved rural areas
HURT hospital utilization review team
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  • hurler-scheie syndrome
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  • hurlers syndrome
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  • Hurler-Scheie syndrome
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CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
hurlbone 1. See Whirlbone.
2. <veterinary> A bone near the middle of the buttock of a horse.
Source: Websters Dictionary
(01 Mar 1998)
Hurler Gertrud, Austrian paediatrician, 1889-1965.
See: Hurler's disease, Hurler's syndrome, Pfaundler-Hurler syndrome.
(05 Mar 2000)
Hurler syndrome <syndrome> A hereditary metabolic disorder, also designated mucopolysaccharidosis I, is caused by a recessive gene which results in a deficiency of the enzyme alpha-L-iduronidase, which breaks down dermatan sulphate and heparan sulphate, two types of mucopolysaccharides (complex carbohydrates). Consequently, the mucopolysaccharides accumulate in the cells of the body and cause damage.
It is characterised by coarse facies, corneal clouding, skeletal dysplasia, hepatosplenomegaly, hernias, mental retardation and early death.
There are mild and severe forms of the syndrome, the mild form is called Scheie Syndrome, the severe form is called Hurler syndrome, and children with an intermediate form have Hurler-Scheie syndrome. Patients with the severe form usually die from respiratory and cardiac failure before the age of ten. There is presently no cure.
Hurler syndrome is one of a number of related rare genetic mucopolysaccharide disorders, the most common being Hunter syndrome.
Diagnosis is possible by observing storage material in tissues, excretion of dermatan sulfate and heparan sulfate in urine, and deficient alpha-L-iduronidase activity in fibroblasts, amniocytes or other cell types.
Missense and other mutations, one of which is relatively common, have been identified in the gene.
Inheritance: autosomal recessive.
(29 Dec 1997)
Hurler's disease <syndrome> Mucopolysaccharidosis in which there is a deficiency of alpha-l-iduronidase, an accumulation of an abnormal intracellular material, and excretion of dermatan sulfate and heparan sulfate in the urine; with severe abnormality in development of skeletal cartilage and bone, with dwarfism, kyphosis, deformed limbs, limitation of joint motion, spadelike hand, corneal clouding, hepatosplenomegaly, mental retardation, and gargoyle-like facies; autosomal recessive inheritance.
See: mucolipidosis.
Synonym: dysostosis multiplex, Hurler's disease, lipochondrodystrophy, Pfaundler-Hurler syndrome, type IH mucopolysaccharidosis.
(05 Mar 2000)
Hurler's syndrome <syndrome> Mucopolysaccharidosis in which there is a deficiency of alpha-l-iduronidase, an accumulation of an abnormal intracellular material, and excretion of dermatan sulfate and heparan sulfate in the urine; with severe abnormality in development of skeletal cartilage and bone, with dwarfism, kyphosis, deformed limbs, limitation of joint motion, spadelike hand, corneal clouding, hepatosplenomegaly, mental retardation, and gargoyle-like facies; autosomal recessive inheritance.
See: mucolipidosis.
Synonym: dysostosis multiplex, Hurler's disease, lipochondrodystrophy, Pfaundler-Hurler syndrome, type IH mucopolysaccharidosis.
(05 Mar 2000)
Hurler-Scheie syndrome <syndrome> Although clinically distinct diseases, fibroblasts from patients with Hurler syndrome and with Scheie syndrome do not cross complement in culture, suggesting that the enzyme defect is the same.
(18 Nov 1997)
huron-iroquous <ethnology> A linguistic group of warlike North American Indians, belonging to the same stock as the Algonquins, and including several tribes, among which were the Five Nations. They formerly occupied the region about Lakes Erie and Ontario, and the larger part of new York.
Source: Websters Dictionary
(01 Mar 1998)
huronian <geology> Of or pertaining to certain non-fossiliferous rocks on the borders of Lake Huron, which are supposed to correspond in time to the latter part of the Archaean age.
Origin: Named from Lake Huron.
Source: Websters Dictionary
(01 Mar 1998)
hurons Sing. Huron.
<ethnology> A powerful and warlike tribe of North American Indians of the Algonquin stock. They formerly occupied the country between Lakes Huron, Erie, and Ontario, but were nearly exterminated by the Five Nations about 1650.
Source: Websters Dictionary
(01 Mar 1998)
hurricane A violent storm, characterised by extreme fury and sudden changes of the wind, and generally accompanied by rain, thunder, and lightning; especially prevalent in the East and West Indies. Also used figuratively. "Like the smoke in a hurricane whirl'd." (Tennyson) "Each guilty thought to me is A dreadful hurricane.
<zoology> " (Massinger) Hurricane bird See Deck.
Origin: Sp. Hurracan; orig. A Carib word signifying, a high wind.
Source: Websters Dictionary
(01 Mar 1998)
hurry The act of hurrying in motion or business; pressure; urgency; bustle; confusion. "Ambition raises a tumult in the soul, it inflames the mind, and puts into a violent hurry of thought." (Addison)
Synonym: Haste, speed, dispatch. See Haste.
Source: Websters Dictionary
(01 Mar 1998)
hurst A wood or grove; a word used in the composition of many names, as in Hazlehurst.
Origin: OE. Hurst, AS. Hyrst; akin to OHG. Hurst, horst, wood, thicket, G. Horst the nest of a bird of prey, an eyerie, thicket.
Source: Websters Dictionary
(01 Mar 1998)
Hurst bougies A series of mercury-filled tubes of graded diameter for dilating the cardioesophageal region.
(05 Mar 2000)
hurt 1. To cause physical pain to; to do bodily harm to; to wound or bruise painfully. "The hurt lion groans within his den." (Dryden)
2. To impar the value, usefulness, beauty, or pleasure of; to damage; to injure; to harm. "Virtue may be assailed, but never hurt." (Milton)
3. To wound the feelings of; to cause mental pain to; to offend in honor or self-respect; to annoy; to grieve. "I am angry and hurt."
Origin: OE. Hurten, hirten, horten, herten; prob. Fr. OF. Hurter, heurter, to knock, thrust, strike, F. Heurter; cf. W. Hyrddu to push, drive, assault, hwrdd a stroke, blow, push; also, a ram, the orig. Sense of the verb thus perhaps being, to butt as a ram; cf. D. Horten to push, strike, MHG. Hurten, both prob. Fr. Old French.
Source: Websters Dictionary
(01 Mar 1998)
hurter A butting piece; a strengthening piece, especially., A piece of wood at the lower end of a platform, designed to prevent the wheels of gun carriages from injuring the parapet.
Origin: F. Heurtoir, lit, a striker. See Hurt.
Source: Websters Dictionary
(01 Mar 1998)
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Hurler's disease Hurler's syndrome: hereditary disease (autosomal recessive) consisting of an error is mucopolysaccharide metabolism; characterized by severe abnormalities in development of skeletal cartilage and bone and mental retardation
Ãâó: wordnet.princeton.edu/perl/webwn
Hurler's syndrome hereditary disease (autosomal recessive) consisting of an error is mucopolysaccharide metabolism; characterized by severe abnormalities in development of skeletal cartilage and bone and mental retardation
Ãâó: wordnet.princeton.edu/perl/webwn
Hurler-Scheie syndrome Clinical spectrum that is intermediate between Hurler and Scheie syndromes. See MPS I
Ãâó: www.mpssociety.org/lib-glossary.html
Hurler-Scheie s. one of the three allelic disorders of mucopolysaccharidosis I, with clinical features intermediate between the Hurler and the Scheie syndromes, caused by deficiency of L-iduronidase, and specifically characterized by receding chin (micrognathism). Symptoms include mental retardation, dwarfism, dysostosis multiplex, corneal clouding, deafness, hernia, stiff joints (claw hand), and valvular heart disease. Patients survive until their late teens or twenties. Called also mucopolysaccharidosis IH/S.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
Hurst d. acute necrotizing hemorrhagic encephalomyelitis.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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HUR the act of jumping over an obstacle
HUR a light movable barrier that competitors must leap over in certain races
HUR an obstacle that you are expected to overcome
HUR jump a hurdle
HUR a footrace in which contestant must negotiate a series of hurdles
HUR an athlete who runs the hurdles
HUR a footrace in which contestant must negotiate a series of hurdles
HUR a footrace in which contestant must negotiate a series of hurdles
HUR a musical instrument that makes music by rotation of a cylinder studded with pegs
HUR a violent throw
HUR utter with force
HUR throw forcefully
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