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"HMG-Box Domains"¿¡ ´ëÇÑ °Ë»ö °á°úÀÔ´Ï´Ù. °Ë»ö °á°ú º¸´Â µµÁß¿¡ Tab ۸¦ ´©¸£½Ã¸é °Ë»ö âÀÌ ¼±Åõ˴ϴÙ.
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CBD Cellulose-binding domains
DD Death domains
RBD RNA binding Domains
MSD membrane spanning domains
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VH and VL genes/domains VH and VL genes define in part the sequences of the variable heavy and light regions of immunoglobulin molecules. VH and VL domains are the regions of amino acid sequence so defined. J genes and, in the case of the heavy chain, a D gene (D=diversity) also define these regions. Gene rearrangement also plays a role in determining the sequences in which the genes are joined as the DNA of the immunoglobulin producing cell matures.
(18 Nov 1997)
SH domains <molecular biology> Src homology domains: domains of protein that, from their homology with src are involved in the interaction with phosphorylated tyrosine residues on other proteins (SH2 domains) or with proline rich sections of other proteins (SH3 domains).
(18 Nov 1997)
src homology domains Regions of sequence similarity in the src family of cytoplasmic tyrosine kinases. The sh1 domain is a catalytic domain. Sh2 and sh3 domains are protein-binding domains. Sh2 usually binds phosphotyrosine-containing proteins and sh3 interacts with cytoskeletal proteins.
(12 Dec 1998)
domains 1. Homologous units of approximately 110 to 120 amino acids each which comprise the light and heavy chains of the immunoglobulin molecule and which serve specific functions. The light chain has two domains's, one in the variable region and one in the constant region of the chain; the heavy chain has four to five domains's, depending upon the class of immunoglobulin, one in the variable region and the remaining ones in the constant region.
2. A region of a protein having some distinctive physical feature or role.
Origin: Fr. Domaine, fr. L. Dominium, property, dominion
(05 Mar 2000)
immunoglobulin domains Structural units of immunoglobulin heavy or light chains that are composed of approximately 110 amino acids. Light chains of an immunoglobulin are composed of one constant domain and one variable domain. Heavy chains are composed of either three or four constant domains and one variable domain.
(05 Mar 2000)
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  • HMG-Box Domains - »õâ DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.)
    Synonyms : HMG-1-Box Domain, High Mobility Group-Box Domains, Domain, HMG-1-Box, Domain, HMG-Box, Domains, HMG-1-Box, Domains, HMG-Box, HMG 1 Box Domain, HMG Box Domains, HMG-1-Box Domains, HMG-Box Domain, High Mobility Group Box Domains
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