| HGF | hepatocyte growth factor; hyperglycemic-glucogenolytic factor |
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| HGFL | hepatocyte growth factor-like [protein] |
| HGF | Hematopoietic growth factor |
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| HGF | Hemopoietic growth factors |
| HGF | Hepatocyte Growth Factor |
| HGF | Hepatocyte Growth Factor-Scatter Factor |
| HGF | Human Gingival Fibroblasts |
| HGF | Hybridoma growth factor |
| HGF-SF | Hepatocyte Growth Factor-Scatter Factor |
| HGFA | HGF activator |
| HGFA | Hepatocyte growth factor activator |
| SF | HGF)/Scatter Factor |
|---|---|
| rHGF | Recombinant HGF |
| SF/HGF | Scatter factor/hepatocyte growth factor |
| rhHGF | recombinant human HGF |
| HGF | <growth factor> Polypeptide mitogen originally shown to cause cell division in hepatocytes. In the liver, the main sources of hepatocyte growth factor are nonparenchymal cells. It is now clear that hepatocyte growth factor is a mitogen for a number of cell types and it is found in many cells outside the liver, including platelets. Hepatocyte growth factor is synthesised as a single chain precursor that is proteolytically cleaved to give a heavy chain (70 kD) and a light chain (30 kD) linked by a single disulphide bond. It contains multiple copies of the kringle domain. However, both the single chain precursor and the two chain forms of hepatocyte growth factor are biologically active and hepatocyte growth factor is generally isolated as a mixture of the two forms. Hepatocyte growth factor also alters cell motility and is now known to be identical to scatter factor. Acronym: HGF (18 Nov 1997) |
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| HGF |
HGF is a growth factor with strong mitogenic activity on hepatocytes and primary epithelial cells through its interaction with its receptor (c-met); HGF has multifunctional activities that regulate cell growth and motility.
Ãâó: www.jco.org/cgi/glossarylookup
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