| 영문 | gout | 한글 | 통풍 |
|---|---|---|---|
| 설명 | 유전정보를 보관하는 물질인 DNA와 RNA 등을 이루는 핵산은 요산의 형태로 배설이 된다. 이것의 배설에는 여러 가지 효소가 작용한다. 이중에서 HGPRT (Hypoxanthine-Guanine Phosphoribosyl Transferase)라는 효소는 이미 배설이 되려고 요산으로 변환하는 과정의 물질을 다시 핵산으로 바꾸는 작용을 하는 효소이다. 통풍이란 이 HGPRT라는 효소 활성도가 감소되어 발생된다. 이 효소의 활성도가 감소되면 핵산의 배설단계에서 재사용이라는 단계가 없어지므로 과도한 요산의 생성이 있게 된다. 혈중에 과도한 요산이 존재하고 이 요산은 결정을 만들어서 관절 주위 및 연부 조직에 침착되어 격심한 발작성 관절통을 야기하는 급성 염증성 관절염을 일으키는 특징적인 병이다. 또 이 요산의 결정들이 콩팥이나 심장에 축적되어서 콩팥 및 심혈관계에 장애가 발생할 수도 있어 내과적 치료를 요하는 병이다. 유전 양식상 보통염색체 우성으로 유전하는 유전병이다. 보통염색체 우성 유전을 하지만 남자와 여자에서 표현률이 달라서 남자가 95%이상을 차지한다. |
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| 영문 | antiglobulin antibody | 한글 | 항글로불린항체 |
|---|---|---|---|
| 설명 | 항체에 대한 항체, 즉 특정 항체와 결합할 수 있는 항체. 대개 인간의 항체를 쥐에 주사하여 쥐로 하여금 인간 항체에 대한 항체를 만들게 한다(쥐에 있어서는 인간의 항체도 외부에서 들어온 물질이므로). 이것은 여러 가지 실험에서 인간의 특정항체를 검출하는데 이용한다. |
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| 영문 | antibody | 한글 | 항체 |
|---|---|---|---|
| 설명 | 사람의 몸에서 면역에 관계하는 물질. 외부에서 들어온 물질과 꼭 맞게 결합을 하여서 그 물질의 생물학적 활동을 억제하거나 파괴하거나 사람의 다른 면역세포로 하여금 공격하기 용이하게 해주는 기능을 가지고 있다. 항체는 면역글로부린이라는 것으로 이루어져 있고 그 형태에 따라 IgA, IgE, IgG, IgD등으로 나눈다. |
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| PCA | para-chloramphetamine; parietal cell antibody; passive cutaneous anaphylaxis; patient care assistant... |
|---|---|
| ACA | abnormal coronary artery; acrodermatitis chronica atrophicans; acute cerebellar ataxia; adenocarcino... |
| ABC | absolute basophil count; absolute bone conduction; acalculous biliary colic; acid balance control; a... |
| PRAGMATIC | pregnancy, rheumatoid arthritis, acromegaly, glucose metabolism disorders, mechanical injury, amyloi... |
| PBA | polyclonal B-cell activity; pressure breathing assist; prolactin-binding assay; prune belly anomaly;... |
| PAB | Polyclonal antibody |
|---|---|
| PPBL | Persistent polyclonal B cell lymphocytosis |
| PAb | Polyclonal |
| PBA | Polyclonal B cell activation |
| PBA | polyclonal B cell activator |
| polyclonal antibody | An antibody produced by several clones of B lymphocytes as would be the case in a whole animal. Usually refers to antibodies raised in immunised animals, whereas a monoclonal antibody is the product of a single clone of B lymphocytes, usually maintained in vitro. (18 Nov 1997) |
|---|---|
| polyclonal | Derived from different types of cells. (14 Nov 1997) |
| polyclonal activator | A substance that will activate T-cells, B-cells, or both regardless of their specificities. (05 Mar 2000) |
| polyclonal antibodies | A group of antibodiesproduced by different B lymphocytes in responseto the same antigen, different antibodies in the group recognise different parts of the antigen. (09 Oct 1997) |
| polyclonal antiserum | A mixture of antibodies to a variety of antigens or to a variety of determinants on a single antigen. (09 Oct 1997) |
| polyclonal compartment | When the progeny of several cells occupy an area or volume with a defined boundary, it is referred to as a polyclonal compartment, for example clones lying close to the mid line of the wing of Drosophila. (18 Nov 1997) |
| arthritis, gout | Joint inflammation caused by uric acid crystal deposits in the joint space An attack is usually extremely painful.The uric acid crystals are deposited in the joint fluid (synovial fluid) and joint lining (synovial lining). Intense joint inflammation occurs as white blood cells engulf the uric acid crystals, causing pain, heat, and redness of the joint tissues. The term gout commonly is used to refer to these painful arthritis attacks but gouty arthritis is only one manifeatation of gout. (12 Dec 1998) |
| calcium gout | <rheumatology> Chondrocalcinosis, chronic recurrent arthritis clinically similar to gout. (27 Sep 1997) |
| masked gout | latent gout |
| retrocedent gout | An obsolete term for the occurrence of severe gastric, cardiac, or cerebral symptoms during an attack of gout, especially when the joint and other symptoms suddenly subside at the same time. Saturnine gout, gout occurring in a person with lead poisoning. Synonym: lead gout. Secondary gout, gout resulting from increased serum uric acid levels as a result of an antecedent disease, such as a proliferative disease of the blood and bone marrow, lead poisoning, or prolonged chronic renal failure (on dialysis). Tophaceous gout, gout in which deposits of uric acid and urates occur as gouty tophi. (05 Mar 2000) |
| gout | <rheumatology> Recurrent acute arthritis of peripheral joints caused by the accumulation of monosodium urate crytals. Often presents as pain and swelling confined to one joint. The big toe joint is commonly affected. The arthritis occurs secondary to an inherited abnormality of purine metabolism, resulting in the deposition of uric acid crystals (sodium urate) within the joint space and articular cartilage. Usually due to overproduction of uric acid but may be a result of under excretion. The problems partly arise because neutrophils release lysosomal enzymes as a result of damage to the phagosome membrane by ingested crystals: colchicine acts to reduce the attack by inhibiting lysosome phagosome fusion. (18 Nov 1997) |
| gout arthritis | <rheumatology> Recurrent acute arthritis of peripheral joints caused by the accumulation of monosodium urate crytals. Often presents as pain and swelling confined to one joint. The big toe joint is commonly affected. The arthritis occurs secondary to an inherited abnormality of purine metabolism, resulting in the deposition of uric acid crystals (sodium urate) within the joint space and articular cartilage. Usually due to overproduction of uric acid but may be a result of under excretion. The problems partly arise because neutrophils release lysosomal enzymes as a result of damage to the phagosome membrane by ingested crystals: colchicine acts to reduce the attack by inhibiting lysosome phagosome fusion. (18 Nov 1997) |
| gout diet | A diet containing a minimal quantity of purine bases (meats); liver, kidney, and sweetbread especially are excluded and replaced by dairy products, fruits, and cereals; alcoholic beverages also are excluded. Synonym: purine-free diet. (05 Mar 2000) |
| gout suppressants | Agents that increase uric acid excretion by the kidney (uricosuric agents), decrease uric acid production (antihyperuricaemics), or alleviate the pain and inflammation of acute attacks of gout. (12 Dec 1998) |
| gout, tophaceous | A form of chronic gout. Nodular masses of uric acid crystals (tophi) are deposited in different soft tissue areas of the body. Even though tophi are most commonly found as hard nodules around the fingers, at the tips of the elbows, and around the big toe, tophi nodules can appear anywhere in the body. They have been reported in unexpected areas such as in the ears, vocal cords, or around the spinal cord! (12 Dec 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|---|---|---|---|
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오에스플러스 - 새창
|
삼천당제약 |
Gout polyclonal anti-rabbit antibody, Mouse monoclonal anti β-HCG antibody, Rabbit Ig | 일반의약품 | 비급여 |
|
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씨티엠베이비첵 - 새창
|
삼천당제약 |
Gout polyclonal anti-rabbit antibody, Mouse monoclonal anti β-HCG antibody, Rabbit Ig | 일반의약품 | 비급여 |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|