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VGCC voltage-gated calcium channels
ROC receiver operating characteristic; receptor-operated channels; relative operating characteristic; re...
GBP scan Gated Blood Pool (cardiac) scan
  = GBPS
  1. LV ±â´É ÃøÁ¤
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GBPS Gated Blood Pool cardiac Scan
  = GBP scan
CNGC cyclic nucleotide gated channel
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KATP channels ATP sensitive K+ channels
K(Ca) channels Ca(2+)-activated K(+) channels
CNG Cyclic nucleotide gated
GBP Gated blood pool
MUGA Multiple gated acquisition
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M channels Voltage sensitive K channels inactivated by acetylcholine. ACh acting at muscarinic AChR's produces an internal messenger that turns off this class of K channel. A mechanism for regulating the sensitivity of cells to synaptic input.
(18 Nov 1997)
chloride channels Cell membrane glycoproteins selective for chloride ions.
(12 Dec 1998)
potassium channels Cell membrane glycoproteins selective for potassium ions.
(12 Dec 1998)
sodium channels Cell membrane glycoproteins selective for sodium ions. Fast sodium current is associated with the action potential in neural membranes.
(12 Dec 1998)
ion channels Gated, ion-selective glycoproteins that traverse membranes. The stimulus for channel gating can be a membrane potential, drug, transmitter, cytoplasmic messenger, or a mechanical deformation. Ion channels which are integral parts of ionotropic neurotransmitter receptors are not included.
(12 Dec 1998)
gated blood pool imaging Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the cycle, using an electrocardiographic synchroniser or gating device. Analysis of right ventricular function is difficult with this technique; that is best evaluated by first-pass ventriculography (ventriculography, first-pass).
(12 Dec 1998)
gated ion channel <physiology> Transmembrane proteins of excitable cells, that allow a flux of ions to pass only under defined circumstances. Channels may be either voltage gated, such as the sodium channel of neurons or ligand gated such as the acetylcholine receptor of cholinergic synapses. Channels tend to be relatively ion specific and allow fluxes of typically 1000 ions to pass in around 1ms, they are thus much faster at moving ions across a membrane than transport ATPases.
(05 May 1997)
gated radionuclide angiocardiography Radionuclide angiocardiography using cardiac gating to combine images from several cardiac cycles to improve the quality of the images of separate phases (e.g., systole and diastole).
(05 Mar 2000)
voltage-gated channel A class of ion channel's that open and close in response to change in the electrical potential across the plasma membrane of the cell; voltage-gated Na+ c.'s are important for conducting action potential along nerve cell processes.
(05 Mar 2000)
voltage gated ion channel <physiology> A transmembrane ion channel whose permeability to ions is extremely sensitive to the transmembrane potential difference. These channels are essential for neuronal signal transmission and for intracellular signal transduction.
See: sodium channel.
(18 Nov 1997)
ligand-gated channel A class of ion channel's whose ionic permeability is regulated by cell membrane receptors that respond to specific extracellular chemical signals.
(05 Mar 2000)
ligand gated ion channel A transmembrane ion channel whose permeability is increased by the binding of a specific ligand, typically a neurotransmitter at a chemical synapse. The permeability change is often drastic, such channels let through effectively no ions when shut, but allow passage at up to 10exp7 ions sexp 1 when a ligand is bound. Recently, the receptors for both acetylcholine and GABA have been found to share considerable sequence homology, implying that there may be a family of structurally related ligand gated ion channels.
(18 Nov 1997)
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