| ¿µ¹® | Gentamicin | ÇÑ±Û | °ÕŸ¸¶À̽Š|
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| GE | gastric empyting; gastroemotional; gastroenteritis; gastroenterology; gastroenterostomy; gastroesoph... |
|---|---|
| GENT | gentamicin |
| AMP | Adenosine Mono-Phosphate |
| amp. | ample |
| AK amp | above-knee amputation |
| CHW | Community Health Worker |
|---|---|
| DBcyclic AMP | Dibutyryl cyclic AMP |
| G | Gentamicin |
| GEN | Gentamicin |
| GM | Gentamicin |
| gentamicin | <drug> A group of aminoglycoside antibiotics produced by Micromonospora spp. Members include the closely related gentamicin compounds C1, C2 and C1a, together with gentamicin A. They inhibit protein synthesis on 70S ribosomes by binding to the 23S core protein of the small subunit, that is responsible for binding mRNA. Mode of action similar to that of kanamycin, neomycin, paromomycin, spectinomycin and streptomycin. Active against strains of the bacterium Pseudomonas aeruginosa. (18 Nov 1997) |
|---|---|
| gentamicin 2'-N-acetyltransferase | <enzyme> An aminoglycoside acetyltransferase; isolated from providencia stuartii; genbank l06156 Registry number: EC 2.3.1.59 Synonym: aac(2')-ia, 2'-n-acetyltransferase, providencia stuartii (26 Jun 1999) |
| gentamicin 2''-nucleotidyltransferase | <enzyme> Chemical name: aminoglycoside 2''-adenylyltransferase Registry number: EC 2.7.7.46 Synonym: gentamycin adenylase, gentamycin adenylyltransferase, aminoglycoside adenylyltransferase, aminoglycoside 2''-o-nucleotidyltransferase, 2''-o-adenylyltransferase, aada2 gene product (26 Jun 1999) |
| sisomicin-gentamicin resistance ribosomal RNA methylase | <enzyme> Catalyses the methylation of 30s ribosomal units to confer sisomicin-gentamicin resistance in micromonospora zionensis Registry number: EC 2.1.1.- Synonym: sgm gene product, sgm methylase (26 Jun 1999) |
| AMP | <abbreviation> Adenosine monophosphate; specifically, the 5'-monophosphate unless modified by a numerical prefix. See: adenylic acid. (05 Mar 2000) |
| AMP-activated protein kinase kinase | <enzyme> An endogenous kinase kinase; reactivates the inactive form of AMP-activated protein kinase (AMP-pk); phosphorylates the 63-kD subunit of AMP-pk Registry number: EC 2.7.1.- Synonym: AMP-pk reactivator, hmg CoA reductase kinase kinase (26 Jun 1999) |
| AMP deaminase | <enzyme> An enzyme that catalyses the deamination of AMP to imp. Chemical name: AMP aminohydrolase Registry number: EC 3.5.4.6 (12 Dec 1998) |
| receptors, cyclic AMP | Cell surface proteins that bind cyclic AMP with high affinity and trigger intracellular changes which influence the behaviour of cells. The best characterised cyclic AMP receptors are those of the slime mold dictyostelium discoideum. The transcription regulator cyclic AMP receptor protein of prokaryotes is not included nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins which are the regulatory subunits of cyclic AMP-dependent protein kinases. (12 Dec 1998) |
| polyphosphate AMP phosphotransferase | <enzyme> From acinetobacter; catalyses (polyphosphate)n and AMP to (polyphosphate)n-1 and ADP Registry number: EC 2.7.4.- Synonym: pamp phosphotransferase (26 Jun 1999) |
| cyclic AMP | <molecular biology> 3'5' cyclic ester of AMP. The first second messenger hormone signalling system to be characterised. Generated from ATP by the action of adenyl cyclase that is coupled to hormone receptors by G-proteins (GTP-binding proteins). CAMP activates a specific (cAMP dependent) protein kinase and is inactivated by phosphodiesterase action giving 5'AMP. Also functions as an extracellular morphogen for some slime moulds. (18 Nov 1997) |
| cyclic AMP-dependent protein kinase | Enzymes which attach phosphate groups to the serine or tyrosine amino acids on proteins as a means of regulating the proteins' activity in metabolic reactions. (09 Oct 1997) |
| cyclic AMP-dependent protein kinases | <enzyme> A group of enzymes that are dependent on cyclic AMP and catalyze the phosphorylation of serine or threonine residues on proteins. Registry number: EC 2.7.10.- (12 Dec 1998) |
| cyclic AMP receptor protein | A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (cyclic AMP receptors), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of cyclic AMP-dependent protein kinases. (12 Dec 1998) |
| dibutyryl cyclic AMP | An analogue of cyclic AMP that shares some of the pharmacological effects of this nucleotide, but is generally believed to enter cells more readily on account of its greater hydrophobicity. (18 Nov 1997) |
| DNA-binding protein, cyclic AMP-responsive | A protein that has been shown to function as a calcium regulated transcription factor as well as a substrate for depolarisation-activated calcium calmodulin-dependent protein kinases I and II. This protein functions to integrate both calcium and camp signals. (12 Dec 1998) |
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