| tretinoin | All-trans retinoic acid |
|---|---|
| FA | Fluocinolone acetonide |
| HQ | 1,4-hydroquinone |
| DTBHQ | 2,5-di(tert-butyl)-1,4-hydroquinone |
| TCHQ | Tetrachloro-p-hydroquinone |
| tretinoin | <chemical> An important regulator of gene expression, particularly during growth and development and in neoplasms. Retinoic acid derived from maternal vitamin a is essential for normal gene expression during embryonic development and either a deficiency or an excess can be teratogenic. It is also a topical dermatologic agent which is used in the treatment of psoriasis, acne vulgaris, and several other skin diseases. It has also been approved for use in promyelocytic leukaemia. Pharmacological action: antineoplastic agent, keratolytic agents. Chemical name: Retinoic acid (12 Dec 1998) |
|---|---|
| fluocinolone acetonide | <chemical> A corticosteroid used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. Pharmacological action: glucocorticoids, synthetic, glucocorticoids, topical. Chemical name: Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)- (12 Dec 1998) |
| hydroquinone | <chemistry> A white crystalline substance, C6H4(OH)2, obtained by the reduction of quinone. It is a diacid phenol, resembling, and metameric with, pyrocatechin and resorcin. Synonym: dihydroxy benzene. Origin: Hydro-, 2 + quinone. Source: Websters Dictionary (01 Mar 1998) |
| 22,6-dichloro-4-hydroquinone chlorohydrolase | <enzyme> Catalyses conversion of 2,6-dichloro-4-hydroquinone to 6-chloro-1,2,4-trihydroxybenzene; isolated from flavobacterium Registry number: EC 3.8.1.- Synonym: 2,6-dich chlorohydrolase, 2,6-dichloro-p-hydroquinone chlorohydrolase (26 Jun 1999) |
| 2,3,5,6-tetrachloro-4-hydroquinone reductive dehalogenase | <enzyme> Uses glutathione to dehalogenate 2,3,5,6-tetrachloro-4-hydroquinone to 2,3,6-trichloro-4-hydroquinone and subsequently to 2,6-dichloro-4-hydroquinone; amino acid sequence has been determined; genbank m98559 Registry number: EC 3.8.1.- Synonym: tech reductive dehalogenase, tetrachloro-p-hydroquinone reductive dehalogenase, pcpc gene product, tetrachlorohydroquinone dehalogenase, tchq dehalogenase (26 Jun 1999) |
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