| ¿µ¹® | steroid | ÇÑ±Û | ½ºÅ×·ÎÀ̵å |
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| ¼³¸í | Hydrogenated cyclopentanoperhydrophenanthrene ring systemÀ¸·Î ±¸¼ºµÈ ºÐÀÚ. »ýü³»¿¡¼ Áß¿äÇÑ ½ºÅ×·ÎÀ̵å´Â ºÎ½Å°ÑÁú¿¡¼ »ý¼ºµÇ´Â ½ºÅ×·ÎÀ̵å È£¸£¸óÀÌ¸ç ´ç´ë»ç¿¡ °ü¿©ÇÏ´Â ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å(glucocorticoid), ¿°·ù´ë»ç(ÀÎü³» Á¸ÀçÇÏ´Â ¿°ºÐ¼ººÐ(NaCl, KCl, NaOH µî)À» Á¶ÀýÇÏ´Â ´ë»ç)¿¡ °ü¿©ÇÏ´Â ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵å(mineralocorticoid), ¼ºÈ£¸£¸ó(ÀÎüÀÇ ¼º¹ß´Þ¿¡ °ü¿©)ÀÇ ¼¼ °¡ÁöÀÌ´Ù. ½ºÅ×·ÎÀ̵å È£¸£¸óÀº ºÎ½ÅÇÇÁú¿¡¼ ÄÝ·¹½ºÅ×·ÑÀ» Àç·á·Î ÇÏ¿© º¹ÀâÇÑ ÇÕ¼º´Ü°è¸¦ °ÅÃÄ ÇÕ¼ºµÈ´Ù. ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å´Â ³úÇϼöü¿¡¼ ºÐºñµÇ´Â ºÎ½Å°ÑÁúÀÚ±Ø È£¸£¸ó(ACTH)¿¡ ÀÇÇØ »ý¼º°ú ºÐºñ°¡ ÀÌ·ç¾îÁö³ª ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵å´Â ·¹´Ñ-¾ÈÁö¿ÀÅٽŰè(½ÅÀå¿¡¼ ÀÎü³» ¿°ºÐÀÌ ºÎÁ·½Ã ·¹´ÑÀÌ ºÐºñµÇ°í, ÀÌ ÀÚ±ØÀº ºÎ½ÅÀ¸·Î ÀüÇØÁ® ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵åÀÎ ¾ÈÁö¿ÀÅÙ½ÅÀ» ºÐºñÇÏ°Ô µÊ)ÀÇ Àڱؿ¡ ÀÇÇØ ºÐºñµÈ´Ù. ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å´Â transcortin°ú °áÇÕÇÏ¿© ¿î¹ÝµÇ¸ç ¹Ý°¨±â´Â Çѽð£ Á¤µµÀ̳ª ¿°·ùÄÚ¸£Æ¼ÄÚÀ̵å´Â ´ëºÎºÐÀÌ ´Ü¹éÁú°ú °áÇÕÇÏÁö ¾Ê°í À¯¸®ÇüÀ¸·Î ³²¾ÆÀÖ¾î ¹Ý°¨±â´Â 20ºÐ¿¡ ºÒ°úÇÏ´Ù. À̵éÀÌ °£¿¡ µµ´ÞÇϸé glucuronic acid¿¡ °áÇÕÇÏ¿© ¹è¼³µÈ´Ù. |
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| ¿µ¹® | blood clotting, blood coagulation | ÇÑ±Û | Ç÷¾×ÀÀ°í |
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| ¼³¸í | »ç¶÷ÀÇ ¸ö¿¡ »óó°¡ ³ª¼ ÃâÇ÷ÀÌ ÀÖÀ» °æ¿ì¿¡ À̰ÍÀ» ¸·°í ÇǸ¦ ´õÀÌ»ó ³ªÁö ¾Ê°Ô ÇÏ´Â °ÍÀ» ÁöÇ÷À̶ó°í ÇÑ´Ù. ÁöÇ÷ÀÇ °úÁ¤¿¡´Â Å©°Ô µÎ °¡Áö ´Ü°è°¡ ÀÖ´Ù. ù¹øÂ° ´Ü°è´Â Ç÷¼ÒÆÇµéÀÌ »óó°¡ ³ª¼ ¼Õ»óµÈ Ç÷°üÀÇ ºÎÀ§¸¦ ¸·´Â °ÍÀÌ´Ù. ÀÌ·¸°Ô ÇÏ¸é ¿ì¼± Ç÷°üÀÇ ¼Õ»óºÎÀ§·Î ºÎÅÍ Çǰ¡ ³ª¿À´Â °ÍÀ» ¸·À» ¼ö°¡ ÀÖ´Ù. ´ÙÀ½ÀÇ ´Ü°è´Â »óó¸¦ ¸·°í ÀÖ´Â Ç÷¼ÒÆÇÀ§¿¡ ¿©·¯ °¡Áö ¹°ÁúµéÀÌ ÀÛ¿ëÇØ¼ ´õ¿í ´Ü´ÜÇÏ°Ô ÇÏ¿© »óó°¡ ³ Ç÷°ü¿¡¼ Çǰ¡ »õ´Â °ÍÀ» ¿µ±¸È÷ ¸·´Â °ÍÀÌ´Ù. ½±°Ô ¸»Çϸé Ç÷¼ÒÆÇÀº º®µ¹¿¡ ÇØ´çÇÏ´Â °ÍÀÌ°í µÎ¹øÂ° °úÁ¤¿¡ Âü¿©ÇÏ´Â ¹°ÁúµéÀº ½Ã¸àÆ®¿¡ ÇØ´çÇÏ´Â °ÍÀÌ´Ù. ÀÌ µÎ °úÁ¤ÀÌ ¿ÏÀüÇÒ °æ¿ì¿¡ ÁöÇ÷ÀÌ ¼øÁ¶·Ó°Ô ÀϾÙ. Ç÷¾×ÀÀ°í¶õ µÎ¹øÂ° ´Ü°è¸¦ ÁöĪÇÏ´Â ¸»·Î½á ¸Å¿ì º¹ÀâÇÑ ´Ü°è¸¦ °ÅÄ¡´Â ¹ÝÀÀÀ¸·Î ¸¶Áö¸· ´Ü°è´Â ¼¶À¯¼Ò¶ó´Â ¹°ÁúÀÌ ¸¸µé¾îÁ®¼ ÀÌ ¹°ÁúÀÌ Ç÷¼ÒÆÇ°ú ±× ¿ÜÀÇ ¼¼Æ÷¸¦ ´Ü´ÜÇÏ°Ô °íÁ¤½ÃÄÑ Çǰ¡ »óó³ Ç÷°üÀ¸·Î »õ´Â °ÍÀ» ¸·´Â´Ù. À̰ÍÀ» °¡Àå °£´ÜÈ÷ ¼³¸íÇÏÀÚ¸é Å©°Ô ´ÙÀ½°ú °°Àº 3°¡Áö ´Ü°è·Î ÀÌ·ç¾îÁø´Ù. ù¹øÂ° ´Ü°è´Â Ç÷°ü¼Õ»ó¿¡ ÀÇÇØ¼ ÇÁ·ÎÆ®·Òºó Ȱ¼ºÁ¦¶ó´Â °ÍÀÌ ¸¸µé¾îÁö´Â ´Ü°èÀÌ´Ù. µÎ¹øÂ° ´Ü°è´Â ÀÌ ÇÁ·ÎÆ®·Òºó Ȱ¼ºÁ¦¶ó´Â ¹°Áú¿¡ ÀÇÇØ¼ Ç÷¾×¼Ó¿¡ ÀÖ´Â ÇÁ·ÎÆ®·ÒºóÀ̶ó´Â ¹°ÁúÀÌ Æ®·ÒºóÀ̶ó´Â ¹°Áú·Î ¹Ù²î´Â ´Ü°èÀÌ´Ù. ¼¼¹øÂ° ´Ü°è´Â Æ®·ÒºóÀ̶ó´Â ¹°Áú¿¡ ÀÇÇØ¼ ¼¶À¯¼Ò¿øÀ̶ó´Â ¹°ÁúÀÌ ¼¶À¯¼ÒÀ¸·Î ¹Ù²î´Â ´Ü°èÀÌ´Ù. |
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| ¿µ¹® | cardiotonic, cardiotonic agent | ÇÑ±Û | °½ÉÁ¦ |
|---|---|---|---|
| ¼³¸í | ½ÉÀåÀÇ ¼öÃà·ÂÀ» Áõ°¨½ÃŰ´Â ¾à¹°À» ¸»ÇÑ´Ù. ±âº»ÀûÀ¸·Î ½É±Ù¼öÃà·ÂÀ» Áõ°½ÃÄÑ ½ÉÀå¹ÚÃâ·®À» Áõ°¡½ÃŰ´Â ¾à¹°ÀÌ´Ù. °½É¹è´çü, Æ÷½ºÆ÷µð¿¡½ºÆ®¶ó¾ÆÁ¦ ¾ïÁ¦Á¦, ¾Æµå·¹³¯¸° ¥â¼ö¿ëüÀÛ¿ëÁ¦, Ç÷°üÈ®ÀåÁ¦ µîÀÌ ÀÖ´Ù. ´ëÇ¥ÀûÀÎ ¿¹·Î¼´Â µð°î½Å(digoxine) µîÀÇ µðÁöÅ»¸®½º(digitalis)°¡ ÀÖ´Ù. |
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| ¿µ¹® | alkylating agent | ÇÑ±Û | ¾ËųȾ๰ |
|---|---|---|---|
| ¼³¸í | Ç×¾ÏÁ¦ÀÇ ÀÏÁ¾. ÀÌ»óÀûÀÎ Ç×¾ÏÁ¦´Â Á¤»óÀûÀÎ ¼¼Æ÷¿¡´Â ÇØ¸¦ ÁÖÁö ¾Ê°í ´ÜÁö ¾Ï¼¼Æ÷¿¡¸¸ Ä¡¸íÀûÀÎ È¿°ú¸¦ ³ªÅ¸³»¾ß ÇÑ´Ù. ÀÌ·¸°Ô ÇÏ·Á¸é ¾Ï¼¼Æ÷¸¸ÀÇ Æ¯ÀÌÇÑ Æ¯¼ºÀ» ÀÌÇØÇÏ°í ±×°÷¿¡¸¸ ÀÛ¿ëÇÏ´Â ¾à¹°À» °³¹ßÇØ¾ß ÇÑ´Ù. ÇöÀç ´ëºÎºÐÀÇ Ç×¾ÏÁ¦´Â ¾Ï¼¼Æ÷°¡ Á¤»ó ¼¼Æ÷¿¡ ºñÇÏ¿© ¿ùµîÈ÷ Áõ½ÄÀ» »¡¸®ÇѴٴ Ư¼ºÀ» ÀÌ¿ëÇϰí ÀÖ´Ù. Áõ½ÄÀÌ ºü¸£´Ù´Â °ÍÀº ´Ù½Ã ¸»Çϸé À¯Àü Á¤º¸¸¦ °¡Áö°í ÀÖ´Â DNAÀÇ º¹Á¦°¡ ºü¸£´Ù´Â °ÍÀ» ÀǹÌÇÑ´Ù. ¸¸¾à DNAÀÇ º¹Á¦¸¦ ¹æÇØÇÑ´Ù¸é Áõ½ÄÀÌ ¾ÆÁÖ ºü¸¥ ¾Ï¼¼Æ÷¿¡°Ô´Â Ä¡¸íÀûÀÌÁö¸¸ ¿µ¿øÈ÷ Áõ½ÄÀ» ÇÏÁö ¾Ê´Â DNAÀÇ º¹Á¦°¡ °ÅÀÇ ÇÊ¿ä¾ø´Â)½Å°æ¼¼Æ÷³ª Áõ½ÄÀÌ ¾Ï¼¼Æ÷¿¡ ºñÇØ¼ ¾ÆÁÖ ´À¸° Á¤»ó¼¼Æ÷¿¡´Â °ÅÀÇ ¿µÇâÀ» ÁÖÁö ¸øÇÑ´Ù. ÇÏÁö¸¸ ½Åü¿¡¼µµ Áõ½ÄÀÌ ¾Ï¼¼Æ÷¿Í ºñ½ÁÇÑ ¼öÁØÀ¸·Î ÀϾ´Â Á¤»óÀûÀÎ ¼¼Æ÷°¡ Àִµ¥ ±×°ÍÀº ¸Ó¸®Ä«¶ôÀ» ¸¸µå´Â ¸ð³¶¼¼Æ÷¿Í ¼ÒȰüÀÇ Á¡¸·À» ÀÌ·ç´Â ¼¼Æ÷¿Í Ç÷¾×ÀÇ ¼¼Æ÷¸¦ ¸¸µå´Â °ñ¼ö ¼¼Æ÷ÀÌ´Ù. ±×·¯¹Ç·Î Ç×¾ÏÁ¦¸¦ »ç¿ëÇÒ °æ¿ì ¾Ï¼¼Æ÷¿Í ¸¶Âù°¡Áö·Î ÀÌµé ¼¼Æ÷µµ ÇÔ²² Ä¡¸íÀûÀÎ ¿µÇâÀ» ÀÔÀ» °ÍÀº ´ç¿¬ÇÏ´Ù(±×·¡¼ Ç×¾ÏÁ¦ Ä¡·á½Ã¿£ ¸Ó¸®°¡ ºüÁö°í ¼ÒȺҷ®ÀÌ Àß ¿Â´Ù). ¾ËĮȾ๰ÀÇ °æ¿ì¿¡´Â DNA¿Í Á÷Á¢ °áÇÕÀ» ÇÏ¿© DNAÀÇ º¹Á¦¸¦ ¾ïÁ¦ÇÔÀ¸·Î½á Ç×¾ÏÁ¦ÀÇ ¿ªÇÒÀ» ¼öÇàÇÑ´Ù. |
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| ¿µ¹® | anti-inflammatory agent | ÇÑ±Û | Ç׿°ÁõÁ¦, ¼Ò¿°Á¦, ¿°Áõ¾à |
|---|---|---|---|
| ¼³¸í | ±¹¼Ò¿¡ ÀÛ¿ëÇÏ¿© ¿°ÁõÀ» Ä¡·áÇÏ°í ¹æÁöÇÏ´Â ¾à. ¿°ÁõÀ» °¡¶ó¾ÉÈ÷´Â ¾àÀ» ¸»ÇÑ´Ù. Á¶Á÷À» ±äÃà-Ä¡¹ÐÇÏ°Ô ÇÏ¿© Àå¾×°ú Á¡¾×ÀÇ ºÐºñ¸¦ ÁÙÀ̰í, Ç¥¸é¿¡ ÀÖ´Â ÀÛÀº Ç÷°ü¿¡ ºóÇ÷À» ÀÏÀ¸ÄÑ ÃæÇ÷µÇ´Â °ÍÀ» ¹æÁöÇÔÀ¸·Î½á ¿°ÁõÀû º´º¯À» Á¦°ÅÇÏ¿© ¸ðµç Áõ¼¼¸¦ ¾ø¾Ø´Ù. ´ëºÎºÐÀÇ ¼ö·ÅÁ¦-¿ÏÈÁ¦-Áø¾çÁ¦°¡ ÀÌ¿¡ ¼ÓÇÑ´Ù. Áß¿äÇÑ ¼ººÐÀ¸·Î´Â ¾Ë·ç¹Ì´½-ºñ½º¹«Æ®-¾Æ¿¬-³³ÈÇÕ¹°(º´¹Ý-Æä¸£¸¶Åç-¾Æ¿¬È-¿¬´ç µî) µîÀÌ ÀÖ´Ù. ÀÛ¿ë¿¡ µû¶ó Ç׿°ÁõÁøÅëÁ¦¿Í Ç׿°ÁõÈ¿¼ÒÁ¦·Î ³ª´¶´Ù. |
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| CBV | capillary blood cell velocity; catheter balloon valvuloplasty; central blood volume; cerebral blood ... |
|---|---|
| SMCA | smooth muscle contracting agent; suckling mouse cataract agent |
| SBP | schizobipolar; serotonin-binding protein; spontaneous bacterial peritonitis; steroid-binding plasma ... |
| C/F | Clinical Finding |
| DOUBTFUL | double quantum transition for finding unresolved lines |
| a | Agent |
|---|---|
| CAA | Chicken anaemia agent |
| FWA | fluorescent whitening agent |
| NMBA | Neuromuscular blocking agent |
| SMA | Snow Mountain Agent |
| finding | 1. That which is found, come upon, or provided; especially. (pl), that which a journeyman artisan finds or provides for himself; as tools, trimmings, etc. "When a man hath been laboring . . . In the deep mines of knowledge, hath furnished out his findings in all their equipage." (Milton) 2. Support; maintenance; that which is provided for one; expence; provision. 3. The result of a judicial examination or inquiry, especially into some matter of fact; a verdict; as, the finding of a jury. "After his friends finding and his rent." (Chaucer) Source: Websters Dictionary (01 Mar 1998) |
|---|---|
| anabolic steroid | <endocrinology> A type of steroid hormone that stimulates the synthesis of protein. Anabolic steroids are compounds which stimulate the body into anabolism. This process involves the building of complex compounds from smaller simpler ones (for example proteins are built from amino acids). This process requires energy. (13 Nov 1997) |
| receptors, steroid | Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behaviour of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes. (12 Dec 1998) |
| gonadal steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| saturated steroid 6 alpha-hydroxylase | <enzyme> Acts on 5 alpha-androstane-3 beta,17 beta-diol and 5 alpha-pregnan-3 beta-ol-20-one; does not require cytochrome p-450 Registry number: EC 1.14.99.- Synonym: sat steroid 6alpha-hydroxylase (26 Jun 1999) |
| sex steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| steroid | A group name for lipids that contain a hydrogenated cyclopentanoperhydrophenanthrene ring system. Some of the substances included in this group are progesterone, adrenocortical hormones, the gonadal hormones, cardiac aglycones, bile acids, sterols (such as cholesterol), toad poisons, saponins and some of the carcinogenic hydrocarbons. (18 Nov 1997) |
| steroid 11-alpha-hydroxylase | <enzyme> Converts 11-deoxycortisol to 11-alpha cortisol (the 11-alpha isomer of hydrocortisone) Registry number: EC 1.14.99.- (26 Jun 1999) |
| steroid 11 beta-monooxygenase | <enzyme> A steroid hydroxylase system found in adrenal tissues. It catalyses the 11-hydroxylation of steroids in the presence of molecular oxygen and consists of an NADPH-specific flavoprotein, a non-haem iron protein, and cytochrome p-450. Its deficiency is a cause of congenital adrenal hyperplasia (adrenal hyperplasia, congenital). Chemical name: Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating) Registry number: EC 1.14.15.4 (12 Dec 1998) |
| steroid 12-monooxygenase | <enzyme> A steroid hydroxylase found in liver microsomes. It catalyses the 12-hydroxylation of steroids in the presence of NADPH, cytochrome p-450, and molecular oxygen. It is an important enzyme in the synthesis of cholic acid from cholesterol in the liver. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (12-alpha-hydroxylating) Registry number: EC 1.14.99.- (12 Dec 1998) |
| steroid 14-alpha-hydroxylase | <enzyme> From induced vegetative cell cultures of mucor piriformis; hydroxylates progesterone to 14-alpha-hydroxyprogesterone in the presence of NADPH and oxygen Registry number: EC 1.14.13.- Synonym: progesterone 14-alpha-hydroxylase (26 Jun 1999) |
| steroid 15-beta-hydroxylase | <enzyme> Contains p-450 and ferredoxin; from bacillus megaterium Registry number: EC 1.14.99.- Synonym: cytochrome p-450 15 beta-hydroxylase, p-450 (15-beta), steroid-15 beta-monooxygenase, cytochrome p-450meg, cytochrome p4502c12, cyp2c12 protein (26 Jun 1999) |
| steroid 17 alpha-monooxygenase | <enzyme> A steroid hydroxylase system found in the microsomal membrane of the steroid-hormone producing tissues. It catalyses the 17-hydroxylation of steroids, such as progesterone or pregnenolone in the presence of NADPH and molecular oxygen. This is an important step in the biosynthesis of steroid hormones. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating) Registry number: EC 1.14.99.9 (12 Dec 1998) |
| steroid 19-hydroxylase | <enzyme> Enzyme from adrenal mitochondria; forms 19-hydroxy-11-deoxycorticosterone Registry number: EC 1.14.13.- Synonym: 19-hydroxysteroid hydroxylase, deoxycorticosterone 11-19-hydroxylase (26 Jun 1999) |
| steroid 21-monooxygenase | <enzyme> A steroid hydroxylase system found in adrenal cortex microsomes. It catalyses the 21-hydroxylation of corticosteroids and shows a requirement for NADPH and molecular oxygen. Its deficiency is a cause of adrenogenital syndrome. Chemical name: Steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating) Registry number: EC 1.14.99.10 (12 Dec 1998) |
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