| AChRs | Acetylcholine Receptors |
|---|---|
| RA | radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal... |
| AR | Alpha1-adrenergic receptors |
|---|---|
| alpha1-ARs | Alpha1-adrenergic receptors |
| beta 2AR | Beta 2-adrenergic receptors |
| CR1 | C3b-C4b receptors |
| CB1 | cannabinoid 1 receptors |
| Fc receptors | <immunology> Receptors for the Fc portion of immunoglobulins. Fc_R (30 kD) is the receptor for serum and secretory IgA1 or IgA2 and is expressed on most myeloid cells and subpopulations of T and B-cells. Fc_RI (CD64) High affinity receptor (72 kD on gels) for monomeric IgG1 found on monocytes, macrophages and some neutrophils. The extracellular portion has three immunoglobulin superfamily C2 domains, in contrast to Fc_RII, Fc_RIII that have only two. Involved in antibody dependent cell killing and in clearance of immune complexes. Fc_RII (CD32) Low affinity receptor 40 kD) for aggregated IgG that exists in several sub types coded by three closely related genes, A, B and C. All forms are found on monocytes, the B forms (that are alternatively spliced) are found on B-cells, the A and C forms are present on neutrophils. Binding of aggregated IgG will trigger phagocytosis and the oxidative burst in neutrophils. Fc_RIII (CD16) is the low affinity receptor (50-80 kD on gels) for aggregated IgG. It is found in transmembrane and GPI linked forms. The transmembrane form associates with the _ subunit of Fc_RI or the TCR_ chain and on B-cells with the _ chain of Fc_RI. Has structural similarity with Fc_RI, Fc_RII and Fc_RI_. Binding of aggregated IgG or IgG antigen complexes mediates phagocytosis or antibody dependent cellular cytotoxicity. Fc_RI is a heteromeric high affinity receptor for IgE found on mast cells and basophils. The _ chain (45-65 kD on gels, 25 kD of polypetide) is N glycosylated and has two immunoglobulin C2 loops in addition to the transmembrane domain, the _ chain (32 kD) has four transmembrane domains, the _ subunit is a homodimer (8 kD monomer) identical to the _ subunit of CD16 and has similarity with _ and _ chains associated with the T-cell receptor. Binding of antigen to the IgE Fc_R complex triggers the release of histamine and various inflammatory mediators. Fc_RIIa & b CD23) Low affinity receptor (45 kD) for IgE. Both a and b are present on mature B-cells, the b form on monocytes, IL-4 activated macrophages, eosinophils, platelets and dendritic cells. The protein has a C type lectin domain that mediates IgE binding and can be cleaved from the membrane to yield an active soluble form. (18 Nov 1997) |
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| adrenergic receptors | Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibres of the sympathetic nervous system. Such receptor's can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptor's are divided into alpha-receptor's and beta-receptor's, on the basis of their response to various adrenergic activating and blocking agents. Synonym: adrenoceptor, adrenoreceptors. (05 Mar 2000) |
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| alpha-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles. (05 Mar 2000) |
| ANP clearance receptors | Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action. (05 Mar 2000) |
| ANP receptors | Cell surface receptors for atrial natriuretic peptide that have a single transmembrane spanning element; these have integral kinase and guanylate cyclase domains. (05 Mar 2000) |
| B-cell antigen receptors | In the primary immune response immunoglobulin D and monomeric immunoglobulin M are the B-cell antigen receptors. On memory B-cells, other immunoglobulin molecules can serve as antigen receptors. (05 Mar 2000) |
| beta-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as propranolol, to block only some adrenergic receptor's and of other agents, such as isoproterenol, to activate only the same adrenergic receptor's. Such receptor's are designated as beta-receptors. Their activation results in physiological responses such as increases in cardiac rate and force of contraction (b1), and relaxation of bronchial and vascular smooth muscle (b2). (05 Mar 2000) |
| mannose-6-phosphate receptors | Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind. (05 Mar 2000) |
| receptors, adrenergic | Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of g-proteins with which they bind; this scheme does not respect the alpha-beta distinction. (12 Dec 1998) |
| receptors, adrenergic, alpha | One of the two major pharmacological subdivisions of adrenergic receptors. The alpha-beta distinction was originally based on cellular effects of receptor activation but now relies on the relative affinities for certain synthetic ligands. Alpha-adrenergic receptors are further subdivided into several subclasses based on studies of endogenous and cloned receptors. (12 Dec 1998) |
| receptors, adrenergic, alpha-1 | A subclass of alpha-adrenergic receptors (receptors, adrenergic, alpha). Alpha-1 adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist phenylephrine and the antagonist prazosin. They are widespread, with clinically important concentrations in the liver, the heart, vascular, intestinal, and genitourinary smooth muscle, and the central and peripheral nervous systems. (12 Dec 1998) |
| receptors, adrenergic, alpha-2 | A subclass of alpha-adrenergic receptors (receptors, adrenergic, alpha). Alpha-2 adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist clonidine and the antagonist yohimbine. They are found on pancreatic beta cells, platelets, and vascular smooth muscle, as well as both pre- and postsynaptically in the central and peripheral nervous systems. (12 Dec 1998) |
| receptors, adrenergic, beta | One of the two major pharmacologically defined classes of adrenergic receptors. The alpha-beta distinction was originally based on the cellular effects of receptor activation but now relies on the relative affinities for characteristic synthetic ligands. Beta adrenergic receptors are further subdivided based on information from endogenous and cloned receptors. (12 Dec 1998) |
| receptors, adrenergic, beta-1 | A subclass of beta-adrenergic receptors (receptors, adrenergic, beta). Beta-1 adrenergic receptors are equally sensitive to epinephrine and norepinephrine and bind the agonist dobutamine and the antagonist metoprolol with high affinity. They are found in the heart, juxtaglomerular cells, and in the central and peripheral nervous systems. (12 Dec 1998) |
| receptors, adrenergic, beta-2 | A subclass of beta-adrenergic receptors (receptors, adrenergic, beta). Beta-2 adrenergic receptors are more sensitive to epinephrine than to norepinephrine and have a high affinity for the agonist terbutaline. They are widespread, with clinically important roles in skeletal muscle, liver, and vascular, bronchial, gastrointestinal, and genitourinary smooth muscle. (12 Dec 1998) |
| receptors, albumin | Cell surface proteins that bind albumin with high affinity and trigger intracellular changes influencing the behaviour of cells. (12 Dec 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|