| ¿µ¹® | sodium | ÇÑ±Û | ³ªÆ®·ý |
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| ¿µ¹® | epithelial tumor | ÇÑ±Û | »óÇǼºÁ¾¾ç |
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| ¿µ¹® | epithelial tissue | ÇÑ±Û | »óÇÇÁ¶Á÷ |
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| ¼³¸í | »óÇÇ´Â ÇÑ Ãþ ¶Ç´Â ¿©·¯ ÃþÀÇ ¼¼Æ÷·Î ÀÌ·ç¾îÁø ÆÇ ¸ð¾çÀÇ ±¸Á¶·Î ½ÅüÀÇ Ç¥¸é°ú °ü»ó±¸Á¶ÀÇ ³»°À» µÑ·¯½Î°í ÀÖ´Ù. »óÇǼ¼Æ÷¿Í »óÇǼ¼Æ÷»çÀÌÀÇ ÀûÀº ¾çÀ¸·Î Á¸ÀçÇÏ¿© »óÇÇ»çÀÌÀÇ °ø°£À» ä¿ì°í ÀÖ´Â ¼¼Æ÷°£ÁúÀ» ÇÕÃÄ »óÇÇÁ¶Á÷À̶ó ÇÑ´Ù. »óÇÇÁ¶Á÷¿¡´Â ¿øÄ¢ÀûÀ¸·Î Ç÷°üÀÌ ºÐÆ÷µÇ¾î ÀÖÁö ¾Ê´Ù. |
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| SCN1A | sodium channel, neuronal alpha-subunit type 1 |
|---|---|
| DOSS | distal over-shoulder strap; dioctyl sodium sulfosuccinate; docusate sodium |
| DSS | dengue shock syndrome; dioctyl sodium sulfosuccinate; Disability Status Scale; discrete subaortic st... |
| PSL | parasternal line; photostimulable luminescence; potassium, sodium chloride, and sodium lactate [solu... |
| SB | Bachelor of Science; Schwartz-Bartter [syndrome]; serum bilirubin; shortness of breath; sick bay; si... |
| KATP channel | ATP sensitive potassium channel |
|---|---|
| BK channel | K channel |
| VGSC | voltage-gated sodium channel |
| ENaC | Epithelial Na+ channel |
| rENaC | rat epithelial Na channel |
channel-shoulder-pin attachment
| sodium channel | <neurology, physiology> The protein responsible for electrical excitability of neurons. A transmembrane ion channel, containing an aqueous pore around 0.4nm diameter, with a negatively charged region internally (the selectivity filter) to block passage of anions. The channel is voltage gated: it opens in response to a small depolarisation of the cell (usually caused by an approaching action potential), by a multistep process. Around 1000 sodium ions pass in the next millisecond, before the channel spontaneously closes (an event with single step kinetics). The channel is then refractory to further depolarisations until returned to near the resting potential. There are around 100 channels per square micron in unmyelinated axons, in myelinated axons, they are concentrated at the nodes of Ranvier. The sodium channel is the target of many of the deadliest neurotoxins. (18 Nov 1997) |
|---|---|
| calcium channel | <physiology> A membrane channel that is specific for calcium. It is a voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorised as l, t, n, or p types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. (12 May 2002) |
| calcium channel agonist | <pharmacology> Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in vascular smooth muscle and/or cardiac muscle cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture. (12 Dec 1998) |
| calcium channel antagonist | <pharmacology> A class of drugs that act by selective inhibition of calcium ion influx through or across cell membranes or on the release and binding of calcium in intracellular pools. Calcium channel blockers are used primarily in the treatment of certain heart conditions and stroke. As they are inducers of vascular and other smooth muscle relaxation, they are also used in the treatment of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms. Synonym: calcium antagonist, calcium channel-blocker, slow channel-blocking agent. (12 May 2002) |
| calcium channel-blocker | <pharmacology> A class of drugs that act by selective inhibition of calcium ion influx through or across cell membranes or on the release and binding of calcium in intracellular pools. Calcium channel blockers are used primarily in the treatment of certain heart conditions and stroke. As they are inducers of vascular and other smooth muscle relaxation, they are also used in the treatment of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms. Synonym: calcium antagonist, calcium channel-blocker, slow channel-blocking agent. (12 May 2002) |
| gated ion channel | <physiology> Transmembrane proteins of excitable cells, that allow a flux of ions to pass only under defined circumstances. Channels may be either voltage gated, such as the sodium channel of neurons or ligand gated such as the acetylcholine receptor of cholinergic synapses. Channels tend to be relatively ion specific and allow fluxes of typically 1000 ions to pass in around 1ms, they are thus much faster at moving ions across a membrane than transport ATPases. (05 May 1997) |
| voltage-gated channel | A class of ion channel's that open and close in response to change in the electrical potential across the plasma membrane of the cell; voltage-gated Na+ c.'s are important for conducting action potential along nerve cell processes. (05 Mar 2000) |
| voltage gated ion channel | <physiology> A transmembrane ion channel whose permeability to ions is extremely sensitive to the transmembrane potential difference. These channels are essential for neuronal signal transmission and for intracellular signal transduction. See: sodium channel. (18 Nov 1997) |
| channel | A furrow, gutter, or groovelike passageway. See: canal. Origin: L. Canalis (05 Mar 2000) |
| channel forming ionophore | <chemistry> An ionophore that makes an amphipathic pore with hydrophobic exterior and hydrophilic interior. most known types are cation selective. (18 Nov 1997) |
| channel gating | <physiology> Small currents in the membrane just prior to the increase in ionic permeability, due to the movement of charged particles within the membrane. So called because they open the gates for current flow through ion channels. (20 Mar 1998) |
| channel islands | A group of four british islands and several islets in the english channel off the coast of france. They are known to have been occupied prehistorically. They were a part of normandy in 933 but were united to the british crown at the time of the norman conquest in 1066. Guernsey and jersey originated noted breeds of cattle. (12 Dec 1998) |
| channel protein | <chemistry, physiology> A protein that facilitates the diffusion of molecules/ions across lipid membranes by forming a hydrophilic pore. most frequently multimeric with the pore formed by subunit interactions. (18 Nov 1997) |
| channel transport | <radiobiology> In inertial fusion research using light ion drivers, describes the use of current-carrying plasma channels (which are magnetically confined to the channel) to transport electron or ion beams between the ion diode and the fusion target. This allows the ion source to stand back from the target. (09 Oct 1997) |
| chloride channel | Ion channels selective for chloride ions. Various types including ligand activated Cl channels at synapses (the GABA and glycine activated channels), as well as voltage gated Cl channels found in a variety of plant and animal cells. See: CFTR, MDR. (18 Nov 1997) |
Synonyms : ENaC (Epithelial Na+ Channel), ENaC alpha, ENaC beta, ENaC delta, ENaC gamma, Epithelial Amiloride-Sensitive Sodium Channel, Epithelial Sodium Channel, alpha Subunit, Epithelial Sodium Channel, beta Subunit, Epithelial Sodium Channel, delta Subunit
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