| 영문 | Gram stain | 한글 | 그람염색 |
|---|---|---|---|
| 설명 | 미생물을 염색하는 방법 중의 하나. 1884년 덴마크의 의사 H.C.J. 그람(1853~ 1938)이 고안한 특수 염색법이다. 이 염색법을 사용하면 미생물은 양성균과 음성균의 2무리로 크게 나뉜다. 염색법은 균을 유리면에 바르고 가열 고정한다. 젠시안바이오렛, 크리스탈 바이오렛, 메틸바이오렛 등 파라로즈 아닐린계 색소의 어느 하나를 사용하여 우선 염색하고 이어서 루골액을 작용시킨 뒤, 에탄올 또는 아세톤으로 탈색한다. 이때 탈색되지 않고 보라색을 타나내는 것을 그람양성균이라 부르며, 포도알균-폐렴알균-사슬알균 등이 대표적인 예이다. 탈색되면 그람음성균이라 부르며, 대장균-녹농균 등이 있다. 최후에 사프라닌, 푹신 등 적색계의 색소액으로 후염색을 한다. 미생물의 감별에 중요한 염색법이며 염색성의 차이는 영양요구성, 화학요법제(항생물질 등)에 대한 감수성의 차이와도 관련되는 점이 많으므로 사용약제의 선택시에도 중요한 역할을 한다. 그람양성균과 음성균의 차이는 세균벽의 구조에 있는데, 양성균은 세포막의 바깥쪽 펩티드글리칸이라는 당단백질층의 두께가 20~80nm나 되고, 그램음성균의 펩티드글리칸 층은 2~3nm로 얇고, 다시 바깥쪽에 외막이라 부르는 층이 있다. |
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| 영문 | deoxyribonucleic acid (DNA) | 한글 | 데옥시리보핵산 |
|---|---|---|---|
| 설명 | 핵산의 일종으로 DNA라고도 한다. Deoxyribonucleotide의 중합체이며 유전자의 화학적 본체이다. RNA바이러스 이외의 모든 생물은 DNA를 유전자로 지니고 있다. 디옥시리보뉴클레오티드(deoxyribonucleotide)는 염기와 당(2'-deoxy-D-ribose)과 인산으로 이루어진다. 염기는 아데닌(adenine), 구아닌(guanine), 티민(thymine)및 시토신(cytosine)의 4가지이며, 이것은 당에 부착되어 있다. 인산 역시 당의 한 부분에 부착되어 있다. 이 deoxyribonucleotide의 당은 다른 deoxy- ribonucleotide의 당과 인산을 사이에 놓고 결합을 하게 되어 하나의 긴 사슬을 형성하게 된다. 즉 당과 인산이 주축이 되어서 deoxyribonucleotide의 긴 사슬을 만든다. 이 deoxyribonucleotide의 사슬 두 개는 각각 deoxyribonucleotide에 부착되어 있는 염기들이 결합을 하여 두 개의 사슬이 결합되어 있는 이중나선 구조를 만들게 된다. 4가지 염기 아데닌은 티민과 결합을 하고, 시토신과 결합을 하게 된다. 즉 당과 인산은 긴 사슬을 만드는 역할을 하고 긴 사슬에 부착된 염기들의 결합에 의해서 두 개의 긴 사슬은 서로 붙어서 이중나선 구조를 만든다. DNA의 유전정보는 염기에 저장된다. 4개의 염기의 조합과 배열이 유전정보를 보관하는 하나의 암호 역할을 행하게 된다. |
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| 영문 | retinoic acid | 한글 | 레티노산 |
|---|---|---|---|
| 설명 | C20H28O2. 비타민 A의 알코올기를 알데히드로 산화한 후 다시 카르복실산으로 산화하여 얻은 산. 발생중의 세포에 작용하여 형태를 만드는데 관여한다. |
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| 영문 | ribonucleic acid | 한글 | 리보핵산 |
|---|---|---|---|
| 설명 | Ribonucleotide monomer로 이루어진 핵산으로 염기, 당, 인산으로 구성된다. 염기는 adenine, guanine, cytosine, uracil의 4종류가 있으며, 당은 5탄당이다. RNA는 DNA를 주형으로 하여 상보적으로 결합, 형성되며 단백질을 만들어내는 데에 있어 중요한 역할을 한다. 전령 RNA(mRNA)는 단백질 합성에 있어 가장 기본이 되는 DNA의 서열을 상보적으로 옮겨 받아 전달하는 전령구실을 하는 RNA. 리보솜 RNA(rRNA) 리보솜을 형성하는 4가지 RNA사슬(28S, 18S, 5.8S, 5S로 구성). 전달 RNA(tRNA) 특정 아미노산을 한쪽 끝에 지니고 상보적 서열의 mRNA와 일시적 결합을 이루며 단백질 합성에 직접 기여하는 RNA이다. |
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| 영문 | acid | 한글 | 산 |
|---|---|---|---|
| 설명 | 물에 녹았을 때 이온화하여 수소 이온을 만드는 물질. 신맛이 나고 청색 리트머스 종이를 붉게 변화시키며 염기와의 중화 반응에 의하여 물과 염을 만들고 이온화 열에서 수소보다 앞에 있는 금속과 반응하여 염을 만들면서 수소를 발생시킨다. 수소 원자를 이온화하는 힘의 강약에 따라 강산과 약산으로 나뉜다. |
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| HE stain | Hematoxylin-Eosin stain |
|---|---|
| AFB Stain | Acid Fast Bacilli Stain |
| H and E | hematoxylin and eosin [stain] |
| HE | half-scan with extrapolation; hard exudate; hektoen enteric [agar]; hemagglutinating encephalomyelit... |
| H&E | hematoxylin and eosin [stain]; hemorrhage and exudate; heredity and environment |
| PTAH | Phosphotungstic acid hematoxylin |
|---|---|
| PWS | Port Wine Stain |
| H&E | Hematoxylin & Eosin |
| EA | Ehrlich Ascites |
| EAC | Ehrlich Ascites Carcinoma |
| Ehrlich's acid haematoxylin stain | <technique> An alum type of haematoxylin stain used as a regressive staining method for nuclei, followed by differentiation to required staining intensity; the solution may be allowed to ripen naturally in sunlight or partially oxidised with sodium iodate. (05 Mar 2000) |
|---|---|
| hematoxylin | <chemical> Basophilic stain that gives a blue colour (to the nucleus of a cell for example), commonly used in conjunction with eosin that stains the cytoplasm pink or red. Various modifications of haematoxylin have been developed. The histopathologist's H&E is haematoxylin and eosin. (18 Nov 1997) |
| Ehrlich's aniline crystal violet stain | <technique> A stain for Gram-positive bacteria. (05 Mar 2000) |
| Ehrlich's triacid stain | <technique> A differential leukocytic stain comprised of saturated solutions of orange G, acid fuchsin, and methyl green. (05 Mar 2000) |
| Ehrlich's triple stain | <technique> A mixture of indulin, eosin Y, and aurantia. (05 Mar 2000) |
| Rambourg's chromic acid-phosphotungstic acid stain | <technique> A stain for glycoproteins, used with an electron microscope, with which ultrathin tissue sections reveal complex carbohydrates in the same locations as shown by Rambourg's periodic acid-chromic methenamine-silver stain. (05 Mar 2000) |
| carcinoma, ehrlich tumour | A transplantable, poorly differentiated malignant tumour which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms. (12 Dec 1998) |
| Paul Ehrlich | <person> A brilliant scientist and student, born in Silesia, Germany, who at the age of 23 published his first scientific paper which was on the discovery of the mast cells - a name coined by him (1887). While a resident in medicine at Charite Hospital in Berlin he utilised the newly discovered aniline dyes to develop some of the basic methods of histology. Among his contributions are: The preparation and staining of blood smears, he demonstrated granules in leukocytes, described the neutrophil, basophil, eosinophil, myelocyte, and mononuclear cells (white blood cells), he demonstrated normoblasts, megaloblasts and microblasts of the erythrocytic (red blood cell) series. In 1887, he differentiated lymphocytic leukaemia from "bone marrow leukaemia" (myeloid) on blood smear, in 1888, he described aplastic anaemia, in 1882 the diazo reaction of typhoid urines, in 1882, less than six weeks after Koch described the Tuberculus bacillus, Ehrlich had described its acid-fastness and devised the fuchsin stain to demonstrate the pink rod on a blue background. Ehrlich fell ill with tuberculosis and went to Egypt for 3 years for rest and cure. Following his return, he entered the field of immunology. at Von Behring's request, he developed means of standardising antitoxin dosage (immunization units). at the age of 42, he became director of the "Royal Institute for Standardisation and Investigation of Antitoxic Sera." Here he devised his famous "side-chain" theory of immunisation. It has since been replaced. Paul Ehrlich reinvestigated Bordet's alexin and heat-stable substance and named them "complement" and "immune body". Ehrlich coined the terms and created a new science of chemotherapy. In 1910 he discovered Salvarsan or 606, a therapeutic antiluetic. For his silver bullet (Salvarsan) in 1908, he received the Nobel Prize. This scientist was greatly concerned over the problem of drug fastness which still remains a problem. He died August 20, 1915. Lived: 1854-1915. (18 Nov 1997) |
| Heinz-Ehrlich body | A round oxyphil body found in the red blood cell in case of haemocytolysis due to a specific blood poison. Synonym: Heinz-Ehrlich body. (05 Mar 2000) |
| Ehrlich | Paul, German bacteriologist, immunologist, and Nobel laureate, 1854-1915. See: Ehrlichia, Ehrlich's anaemia, Ehrlich's inner body, Ehrlich's phenomenon, Ehrlich's postulate, Ehrlich's diazo reagent, Ehrlich's theory, Ehrlich-Turk line. See entries under stain; reaction. (05 Mar 2000) |
| Ehrlich, Paul | <person> A brilliant scientist and student, born in Silesia, Germany, who at the age of 23 published his first scientific paper which was on the discovery of the mast cells - a name coined by him (1887). While a resident in medicine at Charite Hospital in Berlin he utilised the newly discovered aniline dyes to develop some of the basic methods of histology. Among his contributions are: The preparation and staining of blood smears, he demonstrated granules in leukocytes, described the neutrophil, basophil, eosinophil, myelocyte, and mononuclear cells (white blood cells), he demonstrated normoblasts, megaloblasts and microblasts of the erythrocytic (red blood cell) series. In 1887, he differentiated lymphocytic leukaemia from "bone marrow leukaemia" (myeloid) on blood smear, in 1888, he described aplastic anaemia, in 1882 the diazo reaction of typhoid urines, in 1882, less than six weeks after Koch described the Tuberculus bacillus, Ehrlich had described its acid-fastness and devised the fuchsin stain to demonstrate the pink rod on a blue background. Ehrlich fell ill with tuberculosis and went to Egypt for 3 years for rest and cure. Following his return, he entered the field of immunology. at Von Behring's request, he developed means of standardising antitoxin dosage (immunization units). at the age of 42, he became director of the "Royal Institute for Standardisation and Investigation of Antitoxic Sera." Here he devised his famous "side-chain" theory of immunisation. It has since been replaced. Paul Ehrlich reinvestigated Bordet's alexin and heat-stable substance and named them "complement" and "immune body". Ehrlich coined the terms and created a new science of chemotherapy. In 1910 he discovered Salvarsan or 606, a therapeutic antiluetic. For his silver bullet (Salvarsan) in 1908, he received the Nobel Prize. This scientist was greatly concerned over the problem of drug fastness which still remains a problem. He died August 20, 1915. Lived: 1854-1915. (18 Nov 1997) |
| Ehrlich reaction | The reaction of the indole derivatives with aromatic aldehydes; e.g., tryptophan and p-dimethylaminobenzaldehyde in H2SO4 give a red-violet colour useful in assaying proteins for tryptophan content. Synonym: Ehrlich reaction. (05 Mar 2000) |
| Ehrlich's anaemia | <haematology> This form of anaemia occurs when the bone marrow ceases sufficient red and white blood cell production. It may be induced by exposures to high levels of toxic chemicals, radiation and certain drugs. It is generally unresponsive to specific therapy, often accompanied by granulocytopenia and thrombocytopenia, in which the bone marrow may not necessarily be hypocellular or hypoplastic but fails to produce adequate numbers of peripheral blood elements. The term actually is all inclusive and most probably encompasses several clinical syndromes. Origin: Gr. Haima = blood (29 Sep 1997) |
| Ehrlich's benzaldehyde reaction | A test for urobilinogen in the urine, by dissolving 2 g of dimethyl-p-aminobenzaldehyde in 100 ml of 5% hydrochloric acid and adding this reagent to urine; a red colour in the cold indicates the presence of an excessive amount of urobilinogen. (05 Mar 2000) |
| Ehrlich's diazo reaction | The reaction of diazotised sulfanilic acid with bilirubin to form azobilirubin, which forms the basis of quantitating the amount of bilirubin in biological fluids. See: van den Bergh's test. Synonym: Ehrlich's diazo reaction. (05 Mar 2000) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|