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COBRA Consolidated Omnibus Reconciliation Act
CoF cobra factor; cofactor
CoVF cobra venom factor
CT calcitonin; calf testis; cardiac tamponade; cardiothoracic [ratio]; carotid tracing; carpal tunnel; ...
CVF cardiovascular failure; central visual field; cervicovaginal fluid; cobra venom factor
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CVF Cobra Venom Factor
CoF Cobra venom factor
CoVF Cobra venom factor
COBRA Consolidated Omnibus Budget Reconciliation Act of 1985
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egyptian Pertaining to Egypt, in Africa. Egyptian bean.
<botany> A medium-sized tree (Acacia vera). It is one of the chief sources of the best gum arabic.
Origin: L. Aegyptius, Gr, fr. (L. Aegyptus) Egypt: cf. F. Egyptien. Cf. Gypsy.
Source: Websters Dictionary
(01 Mar 1998)
Egyptian haematuria Infection with Schistosoma haematobium, the eggs of which invade the urinary tract, causing cystitis and haematuria, and possibly an increased likelihood of bladder cancer.
Synonym: bladder schistosomiasis, Egyptian haematuria, endemic haematuria, urinary schistosomiasis.
(05 Mar 2000)
Egyptian ophthalmia <ophthalmology> A chronic infectious disease of the conjunctiva and cornea, producing photophobia, pain, lacrimation and blindness.
It is one of the oldest infectious diseases known to mankind, and dates back several thousand years with first documentation as early as the pharaonic era in Egypt.
The disease is associated with poor socioeconomic conditions in general: with overcrowding, poor personal and environmental hygiene and, in particular, with very limited access to water and sanitation. Trachoma has been eliminated as a blinding disease from several previously hyperendemic countries and regions, both through significant improvements in the socioeconomic status of populations and through specific control efforts.
Despite these successes, in many least developed countries of the world blinding trachoma continues to be an important public health problem. In some of the countries where trachoma was once hyperendemic, there remain residual pockets of blinding trachoma and complications, such as inturned eyelashes (trichiasis), which require eyelid surgery.
Today, the disease is found mainly in poor rural areas, including parts of central and south America, most African countries and some countries in the Eastern Mediterranean. Trachoma is still endemic in several Asian countries, but there is a lack of updated information from some major populations, e.g. In India and China.
The organism that causes this disease is Chlamydia trachomatis; a microorganism resembling both bacteria and viruses, which spreads through contact with eye discharge from the infected person (on towels, handkerchiefs, fingers, etc.) and through transmission by eye-seeking flies. Chlamydia trachomatis provokes an inflammatory reaction in the eye with formation of follicles in the conjunctiva. After years of repeated infections, the inside of the eyelids may be scarred so severely that the eyelid turns inwards with eyelashes rubbing on the eyeball. If untreated, this condition leads to blindness.
The World Health Organization is working towards global elimination of trachoma, which is responsible, at present, for at least 15% of the world's blindness. Worldwide, there are about 6 million people largely irreversibly blinded by trachoma, and an estimated 146 million cases of active disease in need of treatment, if blindness is to be prevented.
International efforts to eliminate trachoma as a blinding disease will be based on a combination of interventions known by the acronym "SAFE", which stands for Surgery for trichiasis (inturned eyelashes), Antibiotics, Facial cleanliness and Environmental improvement. These interventions will be community-targeted and will seek community involvement through the primary health care approach.
Origin: Gr. Trachoma = roughness
(07 May 1998)
Egyptian splenomegaly Term sometimes used as a synonym for schistosomiasis mansoni, although hepatomegaly and fibrosis are more consistently found than is an enlarged spleen.
(05 Mar 2000)
cobra A genus of poisonous snakes of the subfamily elapinae of the family elapidae. There are six recognised species, all inhabiting africa except the asiatic (indian) cobra, naja naja. Some species "spit" their venom into the eyes of their "enemies". So-called spitting cobras show a high degree of accuracy in aiming for the eyes. The ringhals, the most highly specialised of the spitting cobras, is limited to southern africa. Its spray destroys eye tissue and can cause blindness; its bite can cause death. (moore: poisonous snakes of the world, 1980, p80)
(12 Dec 1998)
cobra neurotoxins Toxins, contained in cobra (naja) venom that block cholinergic receptors; two specific proteins have been described, the small (short, type I) and the large (long, type II) which also exist in other elapid venoms.
(12 Dec 1998)
cobra toxin A polypeptide of 62 residues; action on cells is similar to that of melittin in that it promotes disruption of membranes; used as an investigational antirheumatic agent.
Synonym: cobra toxin, direct lytic factor of cobra venom.
(05 Mar 2000)
cobra venom cofactor <enzyme> A glycine-rich, heat-labile beta-glycoprotein found in blood. It is a proactivator of complement 3 in the alternate pathway of complement activation. Factor b is converted by factor d to c3 convertase.
Registry number: EC 3.4.21.47
(12 Dec 1998)
cobra venom factor A component of cobra venom that renders C3 proactivator (properdin factor B) susceptible to factor D of the properdin system, leading to activation of C3 and other components of complement and lysis of unsensitised erythrocytes.
(05 Mar 2000)
cobra venoms Venoms from snakes of the genus naja (family elapidae). They contain many specific proteins that have cytotoxic, haemolytic, neurotoxic, and other properties. Like other elapid venoms, they are rich in enzymes. They include cobramines and cobralysins.
(12 Dec 1998)
direct lytic factor of cobra venom A polypeptide of 62 residues; action on cells is similar to that of melittin in that it promotes disruption of membranes; used as an investigational antirheumatic agent.
Synonym: cobra toxin, direct lytic factor of cobra venom.
(05 Mar 2000)
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Egyptian cobra cobra used by the Pharaohs as a symbol of their power over life and death
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