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| AMP | Adenosine Mono-Phosphate |
|---|---|
| amp. | ample |
| AK amp | above-knee amputation |
| AMP | accelerated mental processes; acid mucopolysaccharide; adenosine monophosphate; amphetamine; ampicil... |
| amp | ampere; amplification; ampule; amputation, amputee |
| DBcyclic AMP | Dibutyryl cyclic AMP |
|---|---|
| E | Epinephrine |
| EP | Epinephrine |
| EPI | Epinephrine |
| ADE | arrhythmogenic dose of epinephrine |
| iodate reaction of epinephrine | A reaction dependent upon the oxidation of epinephrine by iodine liberated from iodate, which is decomposed by the hormone; a faint pink colour results. (05 Mar 2000) |
|---|---|
| iodine reaction of epinephrine | A reaction resulting from the oxidation of the hormone, a faint pink colour appearing upon the addition of iodine. (05 Mar 2000) |
| epinephrine | <drug> A cardiac drug used for cardiac arrest from ventricular fibrillation, ventricular tachycardia, asystole, or pulseless electrical activity; extreme hypotension; bradycardia and heart block. Pharmacologic action: 1. Beneficial mainly due to alpha stimulation - increases systemic vascular resistance and improves coronary and cerebral blood flow. 2. Value of beta stimulation is controversial - increases myocardial electrical activity and strength of contraction, but also increases myocardial oxygen requirements and automaticity. Dose: Cardiac arrest: Recommended: 1 mg IV push every 3-5 min Intermediate: 2-5 mg IV push every 3-5 min Escalating: 1 mg, 3 mg, 5 mg IV push 3 min apart High: 0.1 mg/kg IV push every 3-5 min Continuous infusion for bradycardia and severe hypotension: 2 - 10 mcg/min. Epinephrine can be delivered via the endotracheal tube. Increase dose 2-2.5 times IV dose. Potential complications: hypertension and tachycardia, arrhythmias, especially ventricular ectopy, myocardial ischemia. Synonym: adrenaline. (15 Mar 2000) |
| epinephrine cyclase | <enzyme> Epinephrine is converted to adrenochrome Registry number: EC 1.10.3.- Synonym: catecholamine cyclase (26 Jun 1999) |
| epinephrine reversal | The fall in blood pressure produced by epinephrine when given following blockage of alpha-adrenergic receptors by an appropriate drug such as phenoxybenzamine; the vasodilation reflects the ability of epinephrine to activate beta-adrenergic receptors which, in vascular smooth muscle, are inhibitory; in the absence of alpha-receptor blockade, the beta-receptor activation by epinephrine is masked by its predominant action on vascular alpha-receptors, which causes vasoconstriction. Synonym: adrenaline reversal. (05 Mar 2000) |
| ferric chloride reaction of epinephrine | An intense emerald green colour in a neutral or slightly acid solution of epinephrine when ferric chloride is added to it; a reaction typical of catechols. (05 Mar 2000) |
| AMP | <abbreviation> Adenosine monophosphate; specifically, the 5'-monophosphate unless modified by a numerical prefix. See: adenylic acid. (05 Mar 2000) |
| AMP-activated protein kinase kinase | <enzyme> An endogenous kinase kinase; reactivates the inactive form of AMP-activated protein kinase (AMP-pk); phosphorylates the 63-kD subunit of AMP-pk Registry number: EC 2.7.1.- Synonym: AMP-pk reactivator, hmg CoA reductase kinase kinase (26 Jun 1999) |
| AMP deaminase | <enzyme> An enzyme that catalyses the deamination of AMP to imp. Chemical name: AMP aminohydrolase Registry number: EC 3.5.4.6 (12 Dec 1998) |
| receptors, cyclic AMP | Cell surface proteins that bind cyclic AMP with high affinity and trigger intracellular changes which influence the behaviour of cells. The best characterised cyclic AMP receptors are those of the slime mold dictyostelium discoideum. The transcription regulator cyclic AMP receptor protein of prokaryotes is not included nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins which are the regulatory subunits of cyclic AMP-dependent protein kinases. (12 Dec 1998) |
| polyphosphate AMP phosphotransferase | <enzyme> From acinetobacter; catalyses (polyphosphate)n and AMP to (polyphosphate)n-1 and ADP Registry number: EC 2.7.4.- Synonym: pamp phosphotransferase (26 Jun 1999) |
| cyclic AMP | <molecular biology> 3'5' cyclic ester of AMP. The first second messenger hormone signalling system to be characterised. Generated from ATP by the action of adenyl cyclase that is coupled to hormone receptors by G-proteins (GTP-binding proteins). CAMP activates a specific (cAMP dependent) protein kinase and is inactivated by phosphodiesterase action giving 5'AMP. Also functions as an extracellular morphogen for some slime moulds. (18 Nov 1997) |
| cyclic AMP-dependent protein kinase | Enzymes which attach phosphate groups to the serine or tyrosine amino acids on proteins as a means of regulating the proteins' activity in metabolic reactions. (09 Oct 1997) |
| cyclic AMP-dependent protein kinases | <enzyme> A group of enzymes that are dependent on cyclic AMP and catalyze the phosphorylation of serine or threonine residues on proteins. Registry number: EC 2.7.10.- (12 Dec 1998) |
| cyclic AMP receptor protein | A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (cyclic AMP receptors), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of cyclic AMP-dependent protein kinases. (12 Dec 1998) |
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