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    »ó¿°»öü ¿­¼ºÁúȯ(¡­Ö«àõòðü´)
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GAG glycosaminoglycan; group-specific antigen gene
PRAGMATIC pregnancy, rheumatoid arthritis, acromegaly, glucose metabolism disorders, mechanical injury, amyloi...
123I-MIBG 123I-Meta-Iodo-Benzyl-Guanidine
131I-MIBG 131I-Meta-Iodo-Benzyl-Guanidine
MCP Meta-Carpo-Phalangeal
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m-CPP 1-(Meta-chloro)phenylpiperazine
MIBG 123(I)-meta-iodobenzylguanidine
131 I-MIBG 131 I-meta-iodobenzylguanidine
4-META 4-Methacryloxyethyl trimellitate anhydride
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glycosaminoglycan <biochemistry> A macromolecule found on the surface of eukaryotic cells which is thought to play a role in the cells recognition of other cells or of a substrate. It consists of a network of long, branched chains made up of repeating units of disaccharides which contain amino groups sugars, at least one of which has a negatively charged side group (carboxylate or sulphate).
Commonest are hyaluronate (D glucuronic acid N acetyl D glucosamine: MW up to 10 million), chondroitin sulphate (D glucuronic acid N acetyl D galactosamine 4 or 6 sulphate), dermatan sulphate (D glucuronic acid or L iduronic acid N acetyl D galactosamine), keratan sulphate (D galactose N acetyl D glucosamine sulphate) and heparan sulphate (D glucuronic acid or L iduronic acid N acetyl D glucosamine).
Glycosaminoglycan side chains (with the exception of hyaluronate) are covalently attached to a core protein at about every 12 amino acid residues to produce a proteoglycan, these proteoglycans are then noncovalently attached by link proteins to hyaluronate, forming an enormous hydrated space filling polymer found in extracellular matrix. The extent of sulphation is variable and the structure allows tremendous diversity.
The protein is also a component of the capsid of a retrovirus which can act as group-specific antigens to the host.
(14 Oct 1997)
meta- 1. In medicine and biology, a prefix denoting the concept of after, subsequent to, behind, or hindmost.
Compare: post-.
2. In chemistry, an italicised prefix denoting joint, action sharing.
3 (m-). In chemistry, an italicised prefix denoting compound formed by two substitutions in the benzene ring separated by one carbon atom, i.e., linked to the first and third, second and fourth, etc., carbon atoms of the ring. For terms beginning with meta-, or m-, see the specific name.
Origin: G. After, between, over
(05 Mar 2000)
meta-analysis <statistics> A quantitative method of combining the results of independent studies (usually drawn from the published literature) and synthesizing summaries and conclusions which may be used to evaluate therapeutic effectiveness or to plan new studies.
With application chiefly in the areas of research and medicine. It is often an overview of clinical trials. It is usually called a meta-analysis by the author or sponsoring body and should be differentiated from reviews of the literature.
(27 Jun 1999)
o-dihydricphenol meta-O-methyltransferase <enzyme> Involved in flavone glycoside biosynthesis
Registry number: EC 2.1.1.-
Synonym: dhcp-mtf
(26 Jun 1999)
adjustment disorders Maladaptive reactions to identifiable psychosocial stressors occurring within a short time after onset of the stressor. They are manifested by either impairment in social or occupational functioning or by symptoms (depression, anxiety, etc.) that are in excess of a normal and expected reaction to the stressor.
(12 Dec 1998)
affective disorders A class of mental disorder's characterised by a disturbance in mood.
(05 Mar 2000)
affective disorders, psychotic Disorders in which the essential feature is a severe disturbance in mood (depression, anxiety, elation, and excitement) accompanied by psychotic symptoms such as delusions, hallucinations, gross impairment in reality testing, etc.
(12 Dec 1998)
alcohol-related disorders Mental disorders related or resulting from abuse or mis-use of alcohol.
(12 Dec 1998)
amphetamine-related disorders Disorders related or resulting from use of amphetamines.
(12 Dec 1998)
anxiety disorders Disorders in which anxiety (persistent feelings of apprehension, tension, or uneasiness) is the predominant disturbance.
(12 Dec 1998)
articulation disorders Disorders of speech sound production characterised by substitution, omission, and distortion of sounds.
(12 Dec 1998)
auditory perceptual disorders Disorders of auditory perception manifesting as difficulties with auditory memory, speech perception and sound localization. Lesions are usually in the temporal lobe.
(12 Dec 1998)
bowel disorders and fibre High fibre diets help delay the progression of diverticulosis and, at least, reduce the bouts of diverticulitis. In many cases, it helps reduce the symptoms of the Irritable Bowel Syndrome ( IBS ). It is generally accepted that a diet high in fibre is protective, or at least reduces the incidence, of colon polyps and colon cancer.
(12 Dec 1998)
calcium metabolism disorders Disorders in the processing of calcium in the body: its absorption, transport, storage, and utilization.
(12 Dec 1998)
gender identity disorders A class of mental disorders characterised by an incongruity between an assigned culturally determined set of attitudes, behaviour patterns, and physical characteristics associated with masculinity or femininity and gender identity.
See: transsexualism.
(05 Mar 2000)
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