| ¿µ¹® | hypersensitivity | ÇÑ±Û | °ú¹Î, ¿¹¹Î |
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| ¼³¸í | 1. ¾î¶² ¾à¹°À̳ª Àڱؿ¡ ´ëÇÏ¿© °úÀ×¹ÝÀÀÀ» ³ªÅ¸³»´Â ¹æÇâÀ¸·Î ¹ÝÀÀ¼ºÀÌ º¯ÈÇÑ »óÅÂ. °ú¹Î¼º ¹ÝÀÀÀº ¸é¿ª¹ÝÀÀ¿¡ ÀÇÇÏ¿© »ý±â´Â º´Àû °úÁ¤À¸·Î, Áï½ÃÇü¹ÝÀÀ°ú Áö¿¬Çü¹ÝÀÀÀ¸·Î ºÐ·ùµÈ´Ù. ¶ÇÇÑ ´ÙÀ½ÀÇ 4ÇüÀ¸·Î ºÐ·ùµÇ±âµµ ÇÑ´Ù. IÇüÀº Áï½ÃÇü °ú¹Î¼º ¹ÝÀÀ(¿¹ÄÁ´ë anaphylaxis). IIÇüÀº Á¶Á÷Ç׿ø¿¡ ´ëÇÑ Ç×ü¿¡ ÀÇÇÏ¿© »ý±â´Â ¼Õ»ó(¿¹ÄÁ´ë ÄáÆÏµ¶¼º ÄáÆÏ¿°). IIIÇüÀº Ç׿øÇ×üº¹ÇÕ¹°, ƯÈ÷ ¾à°£ÀÇ Ç׿øÀÇ °úÀ׿¡ ÀÇÇÏ¿© Çü¼ºµÇ´Â ¿ëÇØ¼º º¹ÇÕ¹°¿¡ ÀÇÇÏ¿© »ý±â´Â °Í(¿¹ÄÁ´ë ¾Æ¸£Åõ½º ¹ÝÀÀÀ̳ª Ç÷ûº´). IVÇüÀº Áö¿¬Çü °ú¹Ì¼º ¹ÝÀÀ(¿¹ÄÁ´ë Á¢Ã˼º ÇǺκ´)ÀÌ´Ù. 2. °¨°¢À̳ª °¨Á¤ÀÌ Áö³ªÄ¡°Ô ¿¹¹ÎÇÔ. |
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| DNASE, DNAse, | DNase deoxyribonuclease |
|---|---|
| FS | factor of safety; Fanconi syndrome; Felty syndrome; fibromyalgia syndrome; field stimulation; Fisher... |
| HP | Hypersensitivity Pneumonitis = Extrinsic Allergic Alveolitis |
| CBH | chronic benign hepatitis; cutaneous basophilic hypersensitivity |
| CHS | central hypoventilation syndrome; Chediak-Higashi syndrome; cholinesterase; chondroitin sulfate; com... |
| Site 1 | site |
|---|---|
| CAD | Caspase-activated DNase |
| DHS | DNAse I hypersensitive sites |
| DNase | Deoxyribonuclease |
| DNAse I | Deoxyribonuclease I |
| DNAse i hypersensitivity site | <molecular biology> A site on a DNA molecule that is especially prone to being cut apart by the endonuclease enzyme DNase I, which breaks down DNA into smaller fragments by cleaving phosphodiester bonds. These sites tend to be near active genes, which are regularly transcribed. (09 Oct 1997) |
|---|
| anti-DNAse B | This is a serologic blood test used to detect antibodies against antideoxyribonuclease B (anti-DNAse B), an antigen that is produced by group A streptococci. This test is used to document a previous streptococcal infection in those who are suspected of having post-streptococcal disease (for example acute glomerulonephritis, rheumatic fever). A normal value is a negative assay. In adults this is less than 85 Todd units /ml. In school-age children this is less than 170 Todd units/ml. In pre-schoolers this is less than 60 Todd units/ml. Anywhere from 70 to 80% of people with rheumatic fever or post-streptococcal acute glomerulonephritis will have elevated anti-DNAse B levels. The test is performed on a venipuncture specimen. (27 Sep 1997) |
|---|---|
| DNAse | <enzyme> An endonuclease with preference for DNA. Pancreatic DNAse I yields di and oligo nucleotide 5_ phosphates, pancreatic DNAse II yields 3_ phosphates. In chromatin, the sensitivity of DNA to digestion by DNAse I depends on its state of organisation, transcriptionally active genes being much more sensitive than inactive genes. Acronym: DNAase (10 Nov 1998) |
| DNAse footprinting | <molecular biology> A lab technique used to find out which segments of a DNA molecule are protected by DNA-binding proteins from attack by endonuclease enzymes, which break down DNA into smaller fragments by cleaving its phosphodiester bonds. The technique does this with gel electrophoresis to find out which parts of the DNA have sites for proteins to attach to them, by comparing DNA which has been in the presence of DNA-binding proteins with DNA that is pure. (09 Oct 1997) |
| DNAse i | A type of endonuclease, or enzyme that breaks down DNA molecules at their phosphodiester bonds. It is found in large quantities in the pancreas. (09 Oct 1997) |
| DNAse i sensitivity | <molecular biology> The likelihood that a particular DNA segment will be attacked by the endonuclease enzyme DNase I, which breaks down DNA into smaller fragments by cleaving its phosphodiester bonds. DNA segments which contain active genes that are regularly transcribed are more prone to being cut apart by DNase I than inactivated genes, because the inactivated genes are generally within condensed regions of the chromosome, while the active genes are in more open configurations for easy access for transcription. (09 Oct 1997) |
| vasculitis, hypersensitivity | Heterogeneous group of disorders characterised by a vasculitic syndrome presumed to be associated with a hypersensitivity reaction following exposure to an antigen such as an infectious agent, a drug, or other foreign or endogenous substance. (12 Dec 1998) |
| respiratory hypersensitivity | A form of hypersensitivity affecting the respiratory tract. It includes asthma and hay fever. (12 Dec 1998) |
| milk hypersensitivity | Allergic reaction to milk (usually cow's milk) or milk products. In infants the hypersensitivity is manifested by colic, vomiting, diarrhoea, rhinitis, wheezing, etc. Milk hypersensitivity should be differentiated from lactose intolerance, an intolerance to milk as a result of congenital deficiency of lactase. (12 Dec 1998) |
| contact hypersensitivity | <pathology> A type of immune-mediated inflammatory skin rash that results from an allergy to a particular substance (for example jewelry dermatitis, poison ivy, neomycin ointment, etc.). (27 Sep 1997) |
| hypersensitivity | <immunology> A state of altered reactivity in which the body reacts with an exaggerated immune response to a foreign substance. Hypersensitivity reactions are classified as immediate or delayed, types I and IV, respectively, in the Gell and Coombs classification of immune responses. (18 Nov 1997) |
| hypersensitivity, delayed | An increased reactivity to specific antigens mediated not by antibodies but by cells. (12 Dec 1998) |
| hypersensitivity, immediate | Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability. (12 Dec 1998) |
| hypersensitivity pneumonitis | <radiology> Aka: chronic extrinsic allergic alveolitis, pathology: proliferation of epithelial cells, elaboration of reticulum fibres, findings: interstitial reticulonodular pattern (basilar distribution), volume loss (cicatrization atelectasis) in upper lobes, pleural effusion (rare), lymph node enlargement may occur (12 Dec 1998) |
| hypersensitivity reaction | <immunology> The bodys response to an allergic stimulus. This can be localised to one area or generalised and may include: rash, itching, hives, swelling, difficulty breathing, and/or low blood pressure. (27 Sep 1997) |
| hypersensitivity vasculitis | An acute form of vasculitis which may affect the skin only, but also may involve other organs, with a polymorphonuclear infiltrate in the walls of and surrounding small (dermal) vessels. Nuclear fragments are formed by karyorrhexis of the neutrophils. See: leukocytoclastic vasculitis. Synonym: allergic angiitis, hypersensitivity vasculitis. (05 Mar 2000) |
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