| ¿µ¹® | deoxyribonucleic acid (DNA) | ÇÑ±Û | µ¥¿Á½Ã¸®º¸ÇÙ»ê |
|---|---|---|---|
| ¼³¸í | ÇÙ»êÀÇ ÀÏÁ¾À¸·Î DNA¶ó°íµµ ÇÑ´Ù. DeoxyribonucleotideÀÇ ÁßÇÕüÀ̸ç À¯ÀüÀÚÀÇ ÈÇÐÀû º»Ã¼ÀÌ´Ù. RNA¹ÙÀÌ·¯½º ÀÌ¿ÜÀÇ ¸ðµç »ý¹°Àº DNA¸¦ À¯ÀüÀÚ·Î Áö´Ï°í ÀÖ´Ù. µð¿Á½Ã¸®º¸´ºÅ¬·¹¿ÀƼµå(deoxyribonucleotide)´Â ¿°±â¿Í ´ç(2'-deoxy-D-ribose)°ú ÀλêÀ¸·Î ÀÌ·ç¾îÁø´Ù. ¿°±â´Â ¾Æµ¥´Ñ(adenine), ±¸¾Æ´Ñ(guanine), Ƽ¹Î(thymine)¹× ½ÃÅä½Å(cytosine)ÀÇ 4°¡ÁöÀ̸ç, À̰ÍÀº ´ç¿¡ ºÎÂøµÇ¾î ÀÖ´Ù. ÀÎ»ê ¿ª½Ã ´çÀÇ ÇÑ ºÎºÐ¿¡ ºÎÂøµÇ¾î ÀÖ´Ù. ÀÌ deoxyribonucleotideÀÇ ´çÀº ´Ù¸¥ deoxy- ribonucleotideÀÇ ´ç°ú ÀλêÀ» »çÀÌ¿¡ ³õ°í °áÇÕÀ» ÇÏ°Ô µÇ¾î ÇϳªÀÇ ±ä »ç½½À» Çü¼ºÇÏ°Ô µÈ´Ù. Áï ´ç°ú ÀλêÀÌ ÁÖÃàÀÌ µÇ¾î¼ deoxyribonucleotideÀÇ ±ä »ç½½À» ¸¸µç´Ù. ÀÌ deoxyribonucleotideÀÇ »ç½½ µÎ °³´Â °¢°¢ deoxyribonucleotide¿¡ ºÎÂøµÇ¾î ÀÖ´Â ¿°±âµéÀÌ °áÇÕÀ» ÇÏ¿© µÎ °³ÀÇ »ç½½ÀÌ °áÇյǾî ÀÖ´Â ÀÌÁß³ª¼± ±¸Á¶¸¦ ¸¸µé°Ô µÈ´Ù. 4°¡Áö ¿°±â ¾Æµ¥´ÑÀº Ƽ¹Î°ú °áÇÕÀ» Çϰí, ½ÃÅä½Å°ú °áÇÕÀ» ÇÏ°Ô µÈ´Ù. Áï ´ç°ú ÀλêÀº ±ä »ç½½À» ¸¸µå´Â ¿ªÇÒÀ» ÇÏ°í ±ä »ç½½¿¡ ºÎÂøµÈ ¿°±âµéÀÇ °áÇÕ¿¡ ÀÇÇØ¼ µÎ °³ÀÇ ±ä »ç½½Àº ¼·Î ºÙ¾î¼ ÀÌÁß³ª¼± ±¸Á¶¸¦ ¸¸µç´Ù. DNAÀÇ À¯ÀüÁ¤º¸´Â ¿°±â¿¡ ÀúÀåµÈ´Ù. 4°³ÀÇ ¿°±âÀÇ Á¶ÇÕ°ú ¹è¿ÀÌ À¯ÀüÁ¤º¸¸¦ º¸°üÇÏ´Â ÇϳªÀÇ ¾ÏÈ£ ¿ªÇÒÀ» ÇàÇÏ°Ô µÈ´Ù. |
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| ¿µ¹® | DNA | ÇÑ±Û | µð¿Á½Ã¸®º¸ÇÙ»ê, µð¿£¿¡ÀÌ |
|---|---|---|---|
| ¼³¸í | Deoxyribonucleic acidÀÇ ¾à¾î. µ¥¿Á½Ã¸®º¸½º¸¦ ±¸¼º¼ººÐÀ¸·Î ÇÏ´Â ÇÙ»ê. À¯ÀüÀÚÀÇ ÈÇÐÀû º»Å·μ ¿°»öü¿¡ Á¸ÀçÇÑ´Ù. µ¥¿Á½Ã¸®º¸½º¿¡ À¯±â¿°±â¿Í ÀλêÀÌ °áÇÕÇÑ ´ºÅ¬·¹¿ÀƼµå(±¸¼º´ÜÀ§)°¡ Æ÷½ºÆ÷µð¿¡½ºÅ׸£°áÇÕ¿¡ ÀÇÇØ ±ä»ç½½ ÁßÇÕü¸¦ Çü¼ºÇϸç, µÎ °³ÀÇ ±ä»ç½½ÀÌ ¼·Î ºñƲ·Á ²¿ÀÎ ³ª¼±±¸Á¶¸¦ ÃëÇÑ´Ù. µð¿Á½Ã¸®º¸´ºÅ¬·¹¿ÀƼµå(deoxyribonucleotide)´Â ¿°±â¿Í ´ç(2'-deoxy-D-riboe)°ú ÀλêÀ¸·Î ÀÌ·ç¾îÁø´Ù. ¿°±â´Â ¾Æµ¥´Ñ(adenine), ±¸¾Æ´Ñ(guanine), Ƽ¹Î(thymine) ¹× ½ÃÅä½Å(cytosine)ÀÇ ³×°¡ÁöÀ̸ç, À̰ÍÀº ´ç¿¡ ºÎÂøµÇ¾î ÀÖ´Ù. ÀÎ»ê ¿ª½Ã ´çÀÇ ÇÑ ºÎºÐ¿¡ ºÎÂøµÇ¾î ÀÖ´Ù. ÀÌ µð¿Á½Ã¸®º¸´ºÅ¬·¹¿ÀƼµåÀÇ ´çÀº ´Ù¸¥ µð¿Á½Ã¸®º¸´ºÅ¬·¹¿ÀƼµåÀÇ ´ç°ú ÀλêÀ» »çÀÌ¿¡ ³õ°í °áÇÕÇÏ°Ô µÇ¾î ÇϳªÀÇ ±ä »ç½½À» Çü¼ºÇÏ°Ô µÈ´Ù. |
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| ¿µ¹® | virus | ÇÑ±Û | ¹ÙÀÌ·¯½º |
|---|---|---|---|
| ¼³¸í | ¹ÚÅ׸®¾Æº¸´Ù ´ú ÁøÈµÈ, »ý¹°°ú ¹«»ý¹°ÀÇ Áß°£´Ü°è¿¡ ÇØ´çÇÏ´Â °Í. È¥ÀÚ¼´Â »ýÁ¸´É·ÂÀÌ ¾øÀ¸¹Ç·Î ¹Ýµå½Ã ´Ù¸¥ ¼¼Æ÷³»¿¡ ¼ÓÇØ ÀÖ¾î¾ß ÇÑ´Ù. ÀÎü¿¡ ¹ß»ýÇÏ´Â ¸¹Àº º´Áß, ÀÌ ¹ÙÀÌ·¯½º·Î ÀÎÇØ ¹ß»ýÇÏ´Â °æ¿ì°¡ ¸¹À¸¸ç, ÀÌ ¶§ ´ëºÎºÐ ƯÀÌÇÑ Ä¡·á¹ýÀº ¾ø´Â ½ÇÁ¤ÀÌ´Ù. ÀϺΠÇ츣Æä½º¹ÙÀÌ·¯½º °èÅë¿¡´Â Ä¡·á¾àÀÌ °³¹ßµÇ¾î ÀÖÁö¸¸, À̰͵µ ÀϺΠÁúº´¿¡¼¸¸ Ä¡·á°¡ °¡´ÉÇÏ´Ù. ¶ÇÇÑ, Ebstein-Barr virus, Human papilloma virus µîÀº ¾ÏÀÇ ¹ß»ý°ú ¿¬°üµÇ¾î ÀÖÀ¸¸ç, µ¿¹°¿¡¼ ¹ß»ýÇÏ´Â ´ëºÎºÐÀÇ ¾ÏÁ¾Àº ¹ÙÀÌ·¯½º¿Í ¿¬°üµÇ¾î ÀÖ´Â °æ¿ì°¡ ¸¹´Ù. ¿äÁò, ÀϺΠÁö¿ª¿¡¼ Å« À¯ÇàÀ» Çϰí ÀÖ´Â ÈÄõ¼º¸é¿ª°áÇÌÁõÈıº(AIDS)µµ HIV(Human Immunodeficiency Virus)¿Í °ü·ÃÀÌ ÀÖ´Ù. |
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| ¿µ¹® | simian virus | ÇÑ±Û | ¿ø¼þÀ̹ÙÀÌ·¯½º |
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| ¼³¸í | ¿ø¼þÀÌ¿¡¼ ºÐ¸®µÈ ¹ÙÀÌ·¯½º. ¾Æµ¥³ë¹ÙÀÌ·¯½º, ¿£Å׷ιÙÀÌ·¯½º, Ç츣Æä½º¹ÙÀÌ·¯½º ¹× ·¹¿À¹ÙÀÌ·¯½º µîÀÇ ¿©·¯ ±º¿¡ ¼ÓÇÑ´Ù. |
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| ¿µ¹® | influenza virus | ÇÑ±Û | ÀÎÇ÷翣ÀÚ¹ÙÀÌ·¯½º |
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| ¼³¸í | ÀÎÇ÷翣ÀÚÀÇ º´¿øÃ¼. »ó±âµµ Á¡¸·¿¡ ħÀÔÇÏ¿© È£Èí±â ÁúȯÀ» ÀÏÀ¸Å²´Ù. º¸Ã¼ °áÇÕ Ç׿øÀÇ Â÷ÀÌ¿¡ µû¶ó A-B-C ¼¼ÇüÅ·Π³ª´µ¸ç, À¯ÇàÇÒ ¶§¸¶´Ù Ç÷±¸ ÀÀÁý Ç׿øÀÌ º¯ÀÌÇÏ¿© ±¤¹üÀ§ÇÑ À¯ÇàÀ» ³ªÅ¸³½´Ù. ²®ÁúÀÌ ÀÖ´Â 80~150nmÀÇ °ø¸ð¾ç, ³ª¼± ´ëĪ RNA ¹ÙÀÌ·¯½ºÀÌ´Ù. µÎ Á¾·ùÀÇ ½ºÆÄÀÌÅ©, ´º¶ó¹Ì´Ï´Ù¾ÆÁ¦(neuraminidase, NA), ´ç´Ü¹éÁú°ú Ç츶±Û·çƼ´Ñ(hemagglution, HA) ´ç´Ü¹éÁúÀ» ¸¸µç´Ù. AÇüÀÇ NA¿¡´Â N1-N2ÀÇ µÎ Á¾·ù, HA¿¡´Â HAO-HA1-HA2-HA3ÀÇ ³× Á¾·ù°¡ ÀÖ´Ù. AÇüÀº ¸»-µÅÁö-»õ¿¡ °¨¿°ÇÏ¸ç »õ·Î¿î ¾ÆÇüÀº µ¿¹° ¹ÙÀÌ·¯½º¿ÍÀÇ Á¶È¯ÇüÀ̸ç, ±× ¹Û¿¡ µ¿ÀÏ ¾ÆÇü³» Á¡º¯À̰¡ ÀÖ´Ù. B, CÇüÀº »ç¶÷ À̿ܿ¡´Â °¨¿°µÇÁö ¾Ê´Â´Ù. ´ßÀÇ ÀûÇ÷±¸¸¦ ÀÀÁýÇÏ´Â ¼ºÁúÀÌ ÀÖ´Ù. ¹ÙÀÌ·¯½º Áø´Ü¿¡´Â ȯÀÚÀÇ ÀεΠ¼¼Ã´¾×¿¡¼ ºÐ¸®ÇѴٵ簡, ¶Ç´Â ȯÀÚÀÇ Ç÷ûÇ×ü¿¡ ÀÇÇÑ Æ¯ÀÌÀû ÀûÇ÷±¸ ÀÀÁýÀúÁö°Ë»ç, ´º¶ó¹Ì´Ï´Ù¾ÆÁ¦ Ȱ¼ºÀúÁö°Ë»ç ¶Ç´Â ÁßÈ°Ë»ç µîÀ¸·Î °ËÃâÇÑ´Ù. |
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| HEV | health and environment; hemagglutinating encephalomyelitis virus; hepatitis E virus; hepato-encephal... |
|---|---|
| SFV | Semliki Forest virus; shipping fever virus; Shope fibroma virus; squirrel fibroma virus |
| DNA | Deoxyribo-Nucleic Acid |
| DDS | damaged disc syndrome; dendrodendritic synaptosome; dental distress syndrome; depressed DNA synthesi... |
| DNA | deoxyribonucleic acid; did not answer |
| HBV DNA | Hepatitis B virus DNA |
|---|---|
| b-DNA | Branched DNA |
| DNA MTase | DNA methytransferase |
| DNA-MG | DNA Malignancy Grade |
| DNA-PK | DNA dependent protein kinase |
IGF-II : insulin like growth factor-IIÀÇ ¾àÀÚ. ¸¹Àº Àå±â¿Í Á¶Á÷¿¡ ÀÛ¿ëÇÏ¿© ´Ü¹é ÇÕ¼º°ú DNA, RNAÀÇ ÇÕ¼ºÀ» Áõ°¡½ÃÄÑ ¼¼Æ÷ÀÇ ¼ö¿Í ¾çÀ» Áõ°¡
| DNA tumour virus | <oncology, virology> Virus with DNA genome that can cause tumours in animals. Examples are Papovaviridae, Adenoviridae and Epstein Barr virus. (18 Nov 1997) |
|---|---|
| DNA tumour viruses | DNA viruses producing malignant tumours. Of the six major groupings of DNA viruses four contain members which are actually or potentially oncogenic: the adenoviridae, the herpesviridae, the papovaviridae, and the poxviridae. (12 Dec 1998) |
| DNA-directed DNA polymerase | <enzyme> DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair. Chemical name: Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) Registry number: EC 2.7.7.7 (12 Dec 1998) |
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| mammary tumour virus | <organism, virology> Retrovirus that induces mammary carcinoma in mice. Isolated from highly inbred strains that had very high incidence of the tumours, after the discovery that the disease was transmitted by nursing mothers in milk. Endogenous provirus present in germ line of all inbred mice. Transcription of the provirus is regulated by a viral promoter that increases transcription in response to glucocorticoid hormones. May transform by proviral insertion activating the cellular int 1 oncogene (18 Nov 1997) |
| mammary tumour virus of mice | Member of the retrovirus subfamily Oncornavirinae, antigenically distinct from the murine leukaemia-sarcoma complex, that is associated with adenocarcinomatous tumours of the mammary gland, commonly latent in wild and laboratory mice and causing cancer only in genetically susceptible strains under certain hormonal influences. Synonym: Bittner agent, Bittner virus, Bittner's milk factor, mammary cancer virus of mice, milk factor, mouse mammary tumour virus. (05 Mar 2000) |
| RNA tumour virus | The family of retroviruses (Retroviridae) that can cause tumours. They are enveloped by membrane derived from the plasma membrane of the host cell, from which they are released by budding without lysing the cell. Within each virion is a pair of single stranded RNA molecules. Replication involves a DNA intermediate made on an RNA template by the enzyme reverse transcriptase. (18 Nov 1997) |
| mouse mammary tumour virus | Member of the retrovirus subfamily Oncornavirinae, antigenically distinct from the murine leukaemia-sarcoma complex, that is associated with adenocarcinomatous tumours of the mammary gland, commonly latent in wild and laboratory mice and causing cancer only in genetically susceptible strains under certain hormonal influences. Synonym: Bittner agent, Bittner virus, Bittner's milk factor, mammary cancer virus of mice, milk factor, mouse mammary tumour virus. (05 Mar 2000) |
| mouse parotid tumour virus | <virology> A papovavirus (genus Polyomavirus, family Papovaviridae) which is a DNA tumour virus with very small genome. Polyoma was isolated from mice, in which it causes no obvious disease, but when injected at high titre into baby rodents, including mice, it causes tumours of a wide variety of histological types (hence polyoma). In vitro, infected mouse cells are permissive for virus replication and thus are killed, whilst hamster cells undergo abortive infection and at a low frequency become transformed. It is capable of producing parotid tumours in mice and sarcomas in hamsters as well as tumours in other laboratory animals. Synonym: mouse parotid tumour virus. (22 Sep 2002) |
| tumour virus | <oncology, virology> Virus capable of inducing tumours. (18 Nov 1997) |
| tumour virus infections | Infections produced by oncogenic viruses. The infections caused by DNA viruses are less numerous but more diverse than those caused by the RNA oncogenic viruses. (12 Dec 1998) |
| yaba monkey tumour virus | The type species of yatapoxvirus, a tumour-producing DNA virus discovered in monkeys in yaba, nigeria. It has been found to produce histiocytomas in monkeys and humans. (12 Dec 1998) |
| herpes simplex virus DNA polymerase | <enzyme> 3'-5'-exonuclease activity is associated with herpes simplex virus DNA polymerase; interacts with hsv-1 ul42 protein Registry number: EC 3.1.11.- Synonym: hsv DNA polymerase, polymerase associated exonuclease, herpes simplex virus 1 ul30 polymerase, hsv-1 ul30 protein, DNA polymerase ul30, hsv-1 (26 Jun 1999) |
| DNA virus | <molecular biology, virology> A virus in which the nucleic acid is double or single stranded DNA (rather than RNA). Major groups of double stranded DNA viruses are papovaviruses, adenoviruses, herpes viruses, large bacteriophages and poxviruses: of single stranded, parvoviruses and coliphages _X174 and M13. (18 Nov 1997) |
| bovine virus diarrhoea virus | A virus of the genus Pestivirus, in the family Togaviridae, causing bovine virus diarrhoea; New York, Oregon, and Indiana strains of the virus are recognised. Synonym: mucosal disease virus. (05 Mar 2000) |
| acinar cell tumour | A solid and cystic tumour of the pancreas, occurring in young women; tumour cells contain zymogen granules. (05 Mar 2000) |
| acute splenic tumour | Acute splenitis, enlargement, and softening of the spleen, usually due to bacteraemia or severe bacterial toxaemia. (05 Mar 2000) |
| adenoid tumour | Adenoma, or neoplasm with glandlike spaces. (05 Mar 2000) |
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