| 영문 | deoxyribonucleic acid (DNA) | 한글 | 데옥시리보핵산 |
|---|---|---|---|
| 설명 | 핵산의 일종으로 DNA라고도 한다. Deoxyribonucleotide의 중합체이며 유전자의 화학적 본체이다. RNA바이러스 이외의 모든 생물은 DNA를 유전자로 지니고 있다. 디옥시리보뉴클레오티드(deoxyribonucleotide)는 염기와 당(2'-deoxy-D-ribose)과 인산으로 이루어진다. 염기는 아데닌(adenine), 구아닌(guanine), 티민(thymine)및 시토신(cytosine)의 4가지이며, 이것은 당에 부착되어 있다. 인산 역시 당의 한 부분에 부착되어 있다. 이 deoxyribonucleotide의 당은 다른 deoxy- ribonucleotide의 당과 인산을 사이에 놓고 결합을 하게 되어 하나의 긴 사슬을 형성하게 된다. 즉 당과 인산이 주축이 되어서 deoxyribonucleotide의 긴 사슬을 만든다. 이 deoxyribonucleotide의 사슬 두 개는 각각 deoxyribonucleotide에 부착되어 있는 염기들이 결합을 하여 두 개의 사슬이 결합되어 있는 이중나선 구조를 만들게 된다. 4가지 염기 아데닌은 티민과 결합을 하고, 시토신과 결합을 하게 된다. 즉 당과 인산은 긴 사슬을 만드는 역할을 하고 긴 사슬에 부착된 염기들의 결합에 의해서 두 개의 긴 사슬은 서로 붙어서 이중나선 구조를 만든다. DNA의 유전정보는 염기에 저장된다. 4개의 염기의 조합과 배열이 유전정보를 보관하는 하나의 암호 역할을 행하게 된다. |
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| 영문 | DNA | 한글 | 디옥시리보핵산, 디엔에이 |
|---|---|---|---|
| 설명 | Deoxyribonucleic acid의 약어. 데옥시리보스를 구성성분으로 하는 핵산. 유전자의 화학적 본태로서 염색체에 존재한다. 데옥시리보스에 유기염기와 인산이 결합한 뉴클레오티드(구성단위)가 포스포디에스테르결합에 의해 긴사슬 중합체를 형성하며, 두 개의 긴사슬이 서로 비틀려 꼬인 나선구조를 취한다. 디옥시리보뉴클레오티드(deoxyribonucleotide)는 염기와 당(2'-deoxy-D-riboe)과 인산으로 이루어진다. 염기는 아데닌(adenine), 구아닌(guanine), 티민(thymine) 및 시토신(cytosine)의 네가지이며, 이것은 당에 부착되어 있다. 인산 역시 당의 한 부분에 부착되어 있다. 이 디옥시리보뉴클레오티드의 당은 다른 디옥시리보뉴클레오티드의 당과 인산을 사이에 놓고 결합하게 되어 하나의 긴 사슬을 형성하게 된다. |
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| Bmod | behavior modification |
|---|---|
| CM | California mastitis [test]; calmodulin; capreomycin; carboxymethyl; cardiac murmur; cardiac muscle; ... |
| CMS | children's medical services; Christian Medical Society; chronic myelodysplastic syndrome; chromosome... |
| EBM | electrophysiologic behavior modification; epidermal basement membrane; evidence-based medicine; expr... |
| ICD-9-CM | International Classification of Diseases-ninth revision-Clinical Modification |
| DMF | Dose modification factors |
|---|---|
| ICD9CM | International Classification of Diseases 9th Revision Clinical Modification |
| ICD-9 CM | International Classification of Diseases, Ninth Revision, Clinical Modification |
| MDRD | Modification of Diet in Renal Disease |
| R-M | Restriction and modification |
IGF-II : insulin like growth factor-II의 약자. 많은 장기와 조직에 작용하여 단백 합성과 DNA, RNA의 합성을 증가시켜 세포의 수와 양을 증가
| DNA modification | <molecular biology> A variety of chemical changes made to a DNA molecule just after it has been replicated. An example is DNA methylation. (09 Oct 1997) |
|---|---|
| DNA modification methylases | <enzyme> Enzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on either adenine or cytosine residues, in a specific short base sequence in the host cell's own DNA. This methylated sequence will occur many times in the hosT-cell DNA and remain intact for the lifetime of the cell. Any DNA from another species which gains entry into a living cell and lacks the characteristic methylation pattern will be recognised by the restriction endonucleases of similar specificity and destroyed by cleavage. most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. Registry number: EC 2.1.1.- (12 Dec 1998) |
| DNA restriction-modification enzymes | Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage. (12 Dec 1998) |
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| modification | 1. A nonhereditary change in an organism; e.g., one that is acquired from its own activity or environment. 2. A chemical or structural alteration in a molecule. Behaviour modification, the systematic use of principles of conditioning and learning, especially operant or instrumental conditioning, to teach certain skills or to extinguish undesirable behaviours, attitudes, or phobias. Chemical modification, alteration in the structure of a molecule, typically a macromolecule such as a protein, by chemical means; often, the covalent addition by some reagent. Covalent modification, alteration in the structure of a macromolecule by enzymatic means, resulting in a change in the properties of that macromolecule; frequently, this type of modification is physiologically relevant. (05 Mar 2000) |
| modification enzyme | <enzyme, molecular biology> An enzyme that introduces minor bases into DNA or RNA or that alters bases already incorporated. Serves to alter the sequence so that restriction enzymes will not damage the strand. (18 Nov 1997) |
| post-translational modification | The enzymatic processing of a polypeptide chain after translation from messenger RNA and after peptide bond formation has occurred. Examples include glycosylation, acylation, limited proteolysis, phosphorylation, isoprenylation. (10 Oct 1997) |
| ScrFI modification methylase | <enzyme> From lactococcus lactis subsp. Cremoris uc503; recognises sequence ccngg and forms m(5)ccngg; see also DNA modification methylase dsav and DNA modification methylase ssoii Registry number: EC 2.1.1.- Synonym: scrfi methylase (26 Jun 1999) |
| host restriction-modification | A bacterial system where the bacterium is able to destroy invading DNA from a bacteriophage (virus which infects bacteria) while at the same time preventing the destruction of their own DNA. The phage DNA is cleaved by a restriction enzyme made by the bacterium, the bacterial DNA is modified (usually with methylation) so that the enzyme will not destroy it. (09 Oct 1997) |
| Stirling's modification of Gram's stain | <technique> A stable aniline-crystal violet stain. (05 Mar 2000) |
| DNA-directed DNA polymerase | <enzyme> DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair. Chemical name: Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) Registry number: EC 2.7.7.7 (12 Dec 1998) |
| A-DNA | A form of DNA in which the helix is right-handed and the overall appearance is short and broad. (05 Mar 2000) |
| a-form DNA | <molecular biology> One of several forms that can be assumed by a double helix. A-DNA is stable in dehydrated conditions. This form is less common than the dominant form found under physiological conditions -- beta-DNA. This form is also assumed by DNA-RNA hybrid helices and by regions of double-stranded RNA. It is a right-handed helix and is a more compact form than beta-DNA. (09 Oct 1997) |
| antisense DNA | <molecular biology> A synthetic DNA strand that is complementary to a particular strand of target DNA with a complementary sequence of bases. This results in preventing expression of the gene encoded. These proteins can be used to selectively turn off production of certain proteins or block viral genetic instructions, by marking them for destruction by cellular enzymes, in order to prevent the building of new virus or the infection of new cells. (14 Nov 1997) |
| apurinic DNA | <molecular biology> A DNA molecule that has lost adenine and guanine, its purine bases. Apurinic DNA can be produced by treating the DNA with acid. (09 Oct 1997) |
| ATP-dependent DNA strand transferase | <enzyme> From human cell nuclei; catalyses strand exchange between homologous DNA sequences; magnesium dependent, requires ATP hydrolysis Registry number: EC 2.7.7.- Synonym: ATP-dep-DNA-str trnsfase (26 Jun 1999) |
| bacteriophage T7 induced DNA polymerase | <enzyme> Complex of two proteins, phage gene 5 protein and E coli thioredoxin Registry number: EC 2.7.7.- Synonym: t7 phage DNA polymerase, sequenase, t7 DNA polymerase, thermo sequenase (26 Jun 1999) |
| base in DNA | A unit of the DNA. There are 4 bases: adenine (A), guanine (G), thymine (T), and cytosine (C). The sequence of bases (for example, CAG) is the genetic code. (12 Dec 1998) |
Synonyms : Methylases, DNA Modification, Methylases, Modification, Methyltransferases, DNA Modification, Modification Methylases, DNA, Modification Methyltransferases, DNA
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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