| DS | dead air space; dead space; deep sedative; deep sleep; defined substrate; dehydroepiandrosterone sul... |
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| CAAX [box] | protein segment in which C is cysteine, A is usually but not always an aliphatic amino acid, and X i... |
| EVB | electronic view box; esophageal variceal bleeding |
| TATA | Pribnow [box]; tumor-associated transplantation antigen |
| XBP | X-box binding protein |
| DOA | Dead on arrival |
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| RHA | RNA helicase A |
| GBF | G box binding factor |
| KRAB | Kr uppel-associated box |
| PAX | Paired box |
| DEAD box helicase | <enzyme> Family of ATP dependent DNA or RNA helicases with a 4 amino acid consensus, D E A D, that resembles an ATP binding site. Examples, p68, a human nuclear protein involved in cell growth, vasa, a Drosophila protein required for specification of posterior embryonic structures. (18 Nov 1997) |
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| black box | (Jargon) descriptive of a method of reasoning or studying a problem, in which the methods and procedures, as such, are not described, explained, or perhaps even understood: conclusions relate solely to the empirical relationships observed, in some contexts, the term can mean a piece of apparatus or an experimental animal in which the pharmacologic or toxicologic pathway has not yet been worked out. CAAT box, a sequence of nucleotides found in a conserved region of DNA located "upstream" (5' direction) of the start points of eukaryotic transcription units; specific transcription factors appear to associate with it; found in many promoters at -75 bp with the consensus sequence: GG(T/C)CAATCT. Fracture box, an obsolete means of supporting a fractured leg, consisting of a container with only bottom and sides. (05 Mar 2000) |
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| box | <molecular biology> Casual term for a DNA sequence that is a characteristic feature of regions that bind regulatory proteins for example homeobox, TATA box and CAAT box. (18 Nov 1997) |
| box-like heart | <radiology> Ebstein's anomaly, massive cardiomegaly, primarily RA enlargement (12 Dec 1998) |
| CAAT box | <molecular biology> Nucleotide sequence in many eukaryotic promoters usually about 75bp upstream of the start of transcription. Binds NF1. (18 Nov 1997) |
| p68 RNA helicase | <enzyme> An RNA helicase isolated from uv-induced tumours in mice; amino acid sequence has been determined Registry number: EC 2.7.7.- Synonym: dead box helicase p68 (26 Jun 1999) |
| Rad3 ATPase-DNA helicase | <enzyme> Can unwind duplex regions as short as 11 base pairs in a partially duplex circular DNA substrate; on partially duplex linear substrates, the enzyme has a strict 5'--3' polarity with respect to the single strand to which it binds; nicked circular DNA is not utilised; from saccharomyces cerevisiae Registry number: EC 3.6.1.- Synonym: rad3 protein (26 Jun 1999) |
| paired box domain | <molecular biology> Conserved domain of 128 amino acids, found in several developmentally regulated proteins in Drosophila (for example paired, gooseberry, Pox), mouse and human (for example Pax, HuP1, HuP48). (18 Nov 1997) |
| GC box | <molecular biology> A binding site within the promoter region of cells from mammals which has the general nucleotide sequence of GGGCGG and where transcription factors will bind. (20 Mar 1998) |
| matrix-associated helicase | <enzyme> Component of the pre-mRNA splicing complex; has atpase activity and DNA helicase activity on a partially double-stranded DNA substrate in the 3'-5' direction Registry number: EC 2.7.7.- Synonym: helicase mah (26 Jun 1999) |
| CCAAT box | <molecular biology> Consensus sequence for RNA polymerase, found at about 80 bases relative to the transcription start site. Less well conserved than the TATA box. (18 Nov 1997) |
| RepB helicase | <enzyme> Member of the sf2 superfamily of helicases; homologous to rad25/xpb; isolated from dictyostelium discoideum; do not confuse with repb protein; genbank u77065 Registry number: EC 3.1.- Synonym: DNA helicase repb (26 Jun 1999) |
| RepD helicase | <enzyme> Member of the sf2 superfamily of nucleases; homologous to rad3/xpd; isolated from dictyostelium discoideum; do not confuse with repd protein; genbank u77066 Registry number: EC 3.1.- Synonym: DNA helicase repd (26 Jun 1999) |
| RNA helicase | <enzyme> Nuclear envelope-associated RNA helicase activity in nucleocytoplasmic RNA transport; both glh-1 and glh-2 contain cchc-type zinc fingers; xp54 is xenopus homologue of human RNA helicase p54 Registry number: EC 2.7.7.- Synonym: RNA duplex unwindase, p54 gene product, bat1 gene product, RNA helicase a, rok1 protein, human RNA helicase 1, hrh1 protein, mrdb protein, glh-1 protein, glh-2 protein, RNA helicase p54, xp54, u5 snrnp-specific 100-kD protein (26 Jun 1999) |
| Pribnow box | <molecular biology> A region of DNA to which RNA polymerase binds before initiating the transcription of DNA into RNA. The nucleotide at which transcription starts is designated +1 and nucleotides are numbered from this with negative numbers indicating upstream nucleotides and positive downstream nucleotides. most bacterial promoters contain two consensus sequences that seem to be essential for the binding of the polymerase. The first, the Pribnow box, is at about 10 and has the consensus sequence 5' TATAAT 3'. The second, the 35 sequence, is centred about 35 and has the consensus sequence 5' TTGACA 3'. most factors that regulate gene transcription do so by binding at or near the promoter and affecting the initiation of transcription. Much less is known about eukaryote promoters, each of the three RNA polymerases has a different promoter. RNA polymerase I recognises a single promoter for the precursor of rRNA. RNA polymerase II, that transcribes all genes coding for polypeptides, recognises many thousands of promoters. most have the Goldberg Hogness or TATA box that is centred around position 25 and has the consensus sequence 5' TATAAAA 3'. Several promoters have a CAAT box around 90 with the consensus sequence 5' GGCCAATCT 3'. There is increasing evidence that all promoters for housekeeping genes contain multiple copies of a GC rich element that includes the sequence 5' GGGCGG 3'. Transcription by polymerase II is also affected by more distant elements known as enhancers. RNA polymerase III synthesises 5s ribosomal RNA, all tRNAs and a number of small RNAs. The promoter for RNA polymerase III is located within the gene either as a single sequence, as in the 5s RNA gene or as two blocks, as in all tRNA genes. (13 Nov 1997) |
| helicase | <enzyme, molecular biology> A prokaryote enzyme that uses the hydrolysis of ATP to unwind the DNA helix at the replication fork, to allow the resulting single strands to be copied. Two molecules of ATP are required for each nucleotide pair of the duplex. (18 Nov 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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