| CREM | center for rural emergency medicine; cyclic adenosine monophosphate-response element modulator |
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| ECG | Electro-Cardio-Graphy(-Gram); ½ÉÀüµµ = EKG 1. Conducting System Structu... |
| CRE | cumulative radiation effect; cyclic adenosine monophosphate-response element |
| AER | abduction/external rotation; acoustic evoked response; acute exertional rhabdomyolysis; agranular en... |
| SR | sarcoplasmic reticulum; saturation recovery; scanning radiometer; screen; secretion rate; sedimentat... |
| CRE | Cyclic AMP response element |
|---|---|
| CREB | Cyclic AMP response element binding protein |
| CREM | cAMP response element modulator |
| DBcyclic AMP | Dibutyryl cyclic AMP |
| cyclic AMP | 3',5'-cyclic adenosine monophosphate |
| receptors, cyclic AMP | Cell surface proteins that bind cyclic AMP with high affinity and trigger intracellular changes which influence the behaviour of cells. The best characterised cyclic AMP receptors are those of the slime mold dictyostelium discoideum. The transcription regulator cyclic AMP receptor protein of prokaryotes is not included nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins which are the regulatory subunits of cyclic AMP-dependent protein kinases. (12 Dec 1998) |
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| cyclic AMP | <molecular biology> 3'5' cyclic ester of AMP. The first second messenger hormone signalling system to be characterised. Generated from ATP by the action of adenyl cyclase that is coupled to hormone receptors by G-proteins (GTP-binding proteins). CAMP activates a specific (cAMP dependent) protein kinase and is inactivated by phosphodiesterase action giving 5'AMP. Also functions as an extracellular morphogen for some slime moulds. (18 Nov 1997) |
| cyclic AMP-dependent protein kinase | Enzymes which attach phosphate groups to the serine or tyrosine amino acids on proteins as a means of regulating the proteins' activity in metabolic reactions. (09 Oct 1997) |
| cyclic AMP-dependent protein kinases | <enzyme> A group of enzymes that are dependent on cyclic AMP and catalyze the phosphorylation of serine or threonine residues on proteins. Registry number: EC 2.7.10.- (12 Dec 1998) |
| cyclic AMP receptor protein | A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (cyclic AMP receptors), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of cyclic AMP-dependent protein kinases. (12 Dec 1998) |
| dibutyryl cyclic AMP | An analogue of cyclic AMP that shares some of the pharmacological effects of this nucleotide, but is generally believed to enter cells more readily on account of its greater hydrophobicity. (18 Nov 1997) |
| DNA-binding protein, cyclic AMP-responsive | A protein that has been shown to function as a calcium regulated transcription factor as well as a substrate for depolarisation-activated calcium calmodulin-dependent protein kinases I and II. This protein functions to integrate both calcium and camp signals. (12 Dec 1998) |
| 3',5'-cyclic AMP synthetase | <enzyme> Enzyme responsible for the ATP. (06 May 1997) |
| heat-shock response element | <cell biology, protein> The nucleotide sequence, CNNGAANNTCCNG, which is in the promoter region of the heat-shock genes. When the animal is exposed to certain types of stress such as a sudden rise in temperature, the first thing that happens to activate these genes is the binding of the HSE by a transcriptional enhancer protein. (09 Oct 1997) |
| serum response element | Dyad symmetry element bound by serum response factor to control the expression of c fos. (18 Nov 1997) |
| modulator | A specific inductor that brings out characteristics peculiar to a definite region. (18 Nov 1997) |
| selective oestrogen-receptor modulator | <pharmacology> An antioestrogen which possesses some, but not all, of the actions of oestrogen. For example, raloxifene (evista) is classified as a SERM because it prevents bone loss (like oestrogen) and lowers serum cholesterol (like oestrogen) but (unlike oestrogen) does not stimulate the endometrial lining of the uterus. Acronym: SERM (17 Jul 2002) |
| AMP | <abbreviation> Adenosine monophosphate; specifically, the 5'-monophosphate unless modified by a numerical prefix. See: adenylic acid. (05 Mar 2000) |
| AMP-activated protein kinase kinase | <enzyme> An endogenous kinase kinase; reactivates the inactive form of AMP-activated protein kinase (AMP-pk); phosphorylates the 63-kD subunit of AMP-pk Registry number: EC 2.7.1.- Synonym: AMP-pk reactivator, hmg CoA reductase kinase kinase (26 Jun 1999) |
| AMP deaminase | <enzyme> An enzyme that catalyses the deamination of AMP to imp. Chemical name: AMP aminohydrolase Registry number: EC 3.5.4.6 (12 Dec 1998) |
Synonyms : CREM Protein, alpha Isoform, CREM Protein, epsilon Isoform, CREM Protein, gamma Isoform, CREM Protein, tau Isoform, ICERIIgamma, ICERIgamma, Inducible cAMP Early Regulator, cAMP Responsive Element Modulator
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