| SSC | single-strand conformational [analysis]; sister strand crossover; somatosensory cortex; standard sal... |
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| DSB | double-strand break |
| SSB | short spike burst; sicca syndrome B; single-strand break; single-stranded binding [protein]; stereos... |
| W-C | Watson-Crick |
|---|---|
| DNA-SSB | DNA single strand break |
| DSB | Double strand break |
| DS | Double-strand |
| DSB | Double-strand DNA break |
| Watson-Crick helix | The helical structure assumed by two strands of deoxyribonucleic acid, held together throughout their length by hydrogen bonds between bases on opposite strands, referred to as Watson-Crick base pairing. See: base pair. Synonym: DNA helix, double helix, twin helix. (05 Mar 2000) |
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| Crick | Francis H.C., British biochemist and Nobel laureate, *1916. See: Watson-Crick helix. (05 Mar 2000) |
| Crick, Francis | <person> An English biologist born in 1916 who was one of three people to win the Nobel Prize in 1962 for the category of physiology or medicine. He and James Watson, an American biochemist and alumnus of Indiana University, discovered the double-stranded helix structure of the DNA molecule and built the Watson-Crick model of this structure. Their work was heavily based on the work of Maurice Wilkins (who also won the Nobel Prize in physiology or medicine in 1962) and Rosalind Franklin (who died before the 1962 Nobel Prize winners were selected). The model they postulated is the accepted model used today. Lived: 1916- (13 Nov 1997) |
| Francis Crick | <person> An English biologist born in 1916 who was one of three people to win the Nobel Prize in 1962 for the category of physiology or medicine. He and James Watson, an American biochemist and alumnus of Indiana University, discovered the double-stranded helix structure of the DNA molecule and built the Watson-Crick model of this structure. Their work was heavily based on the work of Maurice Wilkins (who also won the Nobel Prize in physiology or medicine in 1962) and Rosalind Franklin (who died before the 1962 Nobel Prize winners were selected). The model they postulated is the accepted model used today. Lived: 1916- (13 Nov 1997) |
| anticoding strand | The strand of duplex DNA which is used as a template for the synthesis of mRNA. Synonym: antisense strand. (05 Mar 2000) |
| antiparallel strand | A macromolecular strand that is oriented in the opposite direction of a neighboring strand. (05 Mar 2000) |
| antisense strand | <molecular biology> The strand of DNA which is not used during transcription to make mRNA (anticoding strand). The mRNA made during transcription thus has the same sequence as this strand, so that the eventual protein will be a sense version. (13 Jan 1998) |
| ATP-dependent DNA strand transferase | <enzyme> From human cell nuclei; catalyses strand exchange between homologous DNA sequences; magnesium dependent, requires ATP hydrolysis Registry number: EC 2.7.7.- Synonym: ATP-dep-DNA-str trnsfase (26 Jun 1999) |
| viral strand | See: replicative form. (05 Mar 2000) |
| minus strand | See: replicative form. (05 Mar 2000) |
| minus-strand nucleic acid | <molecular biology> An RNA or DNA strand which has the opposite sense of (would be complementary to) the mRNA of a virus. (12 Jan 1998) |
| coding strand | The strand of duplex DNA that has the same sequence as the mRNA (except that mRNA contains ribonucleotides instead of deoxyribonucleotides). Synonym: sense strand. (05 Mar 2000) |
| complementary strand | See: replicative form. (05 Mar 2000) |
| plus strand | See: replicative form. (05 Mar 2000) |
| positive strand RNA viruses | Class IV and VI viruses that have a single stranded RNA genome that can act as mRNA plus strand) and in which the virus RNA is itself infectious. Includes Picornaviridae, Togaviridae and Retroviridae. (18 Nov 1997) |
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