| 영문 | Coombs test | 한글 | 크움즈검사 |
|---|---|---|---|
| 설명 | 적혈구에 대한 항체를 검사하는 방법. 항체란 특정한 물질에 부착되어 그 물질의 작용을 억제하고, 또는 그 물질을 파괴하는 것으로 B-림프구라는 면역을 담당하는 세포에 의해서 만들어진다. 이 크움즈검사에는 직접크움즈검사와 간접크움즈검사의 두 가지가 있는데 직접 크움즈검사는 몸속의 적혈구에 직접 부착되어 있는 항체를 검사하는 방법이다. 채취한 혈액을 적혈구를 얻어서 사람의 항체에 대한 항체(사람의 항체에 특정하게 부착이 되는 항체)를 반응시키면, 만약 적혈구에 대한 항체가 부착되어 있는 적혈구라면 사람의 항체에 대한 항체가, 작용하여 침강 반응이 일어나게 되고 항체가 부착되어 있지 않는 적혈구이면 반응이 일어나지 않는 것을 이용한다. 간접크움즈검사는 혈장속에 존재하는 적혈구와 부착되어 있지 않은 항체를 찾아내는 시험으로 혈장을 채취해서 다른 사람의 적혈구와 반응을 시키고 역시 항체에 대한 항체를 반응시켜 침강반응을 관찰해서 그 항체를 찾아내는 방법이다. |
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| AGT | Anti-Globulin Test = Coombs' Test |
|---|---|
| ISI | International Sensitivity Index of reagent/instrument combination |
| AR | absolute risk; accounts receivable; achievement ratio; actinic reticuloid [syndrome]; active resista... |
| BH | base hospital; benzalkonium and heparin; bill of health; birth history; Bishop-Harman [instruments];... |
| CT | calcitonin; calf testis; cardiac tamponade; cardiothoracic [ratio]; carotid tracing; carpal tunnel; ... |
| PAS | Periodic acid-Schiff reagent |
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| Carey Coombs murmur | A blubbering apical middiastolic murmur occurring in the acute stage of rheumatic mitral valvulitis and disappearing as the valvulitis subsides. Synonym: Coombs murmur. (05 Mar 2000) |
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| Gell and Coombs Classification | A classification system that differentiates the 4 types of hypersensitivity reactions: Type I: anaphylactic reactions, Type II: cytotoxic reactions, Type III: immune complex reactions, and Type IV: cell-mediated reactions. (05 Mar 2000) |
| Coombs, Carey | <person> English physician, 1879-1932. See: Coombs murmur. (05 Mar 2000) |
| Coombs murmur | A blubbering apical middiastolic murmur occurring in the acute stage of rheumatic mitral valvulitis and disappearing as the valvulitis subsides. Synonym: Coombs murmur. (05 Mar 2000) |
| coombs' reaction | An immunological lab test to detect antibodies which attack the red blood cells of its own body (called autoantibodies). The test is important to the diagnosis of certain blood disorders. The test first reacts red blood cells with serum from the test individual, then with antibodies to the autoantibodies. If the autoantibodies exist, they will bind to the red blood cells. When the antibodies to the autoantibodies are added, they will bind the autoantibodies (still attached to the red blood cells) and cause the red blood cells to clump together. Large clumps of red blood cells indicate that the autoantibodies exist, absence of the clumps indicates that they don't. (09 Oct 1997) |
| Coombs, Robin | <person> English veterinarian and immunologist, *1921. See: Gell and Coombs reactions, Coombs' serum, Coombs' test, direct Coombs' test, indirect Coombs' test. (05 Mar 2000) |
| Coombs' serum | Serum from a rabbit or other animal previously immunised with purified human globulin to prepare antibodies directed against IgG and complement; used in the direct and indirect Coombs' tests. Synonym: Coombs' serum. (05 Mar 2000) |
| coombs' test | Haemagglutination test in which coombs' reagent (antiglobulin, or anti-human globulin rabbit immune serum) is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which have been coated with antibody in vivo (e.g., in haemolytic disease of newborn, autoimmune haemolytic anaemia, and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection of antibodies not identifiable by other means). (12 Dec 1998) |
| direct Coombs' test | A test for detecting sensitised erythrocytes in erythroblastosis foetalis and in cases of acquired immune haemolytic anaemia: the patient's erythrocytes are washed with saline to remove serum and unattached antibody protein, then incubated with Coombs' anti-human globulin (usually serum from a rabbit or goat previously immunised with human globulin); after incubation, the system is centrifuged and examined for agglutination, which indicates the presence of so-called incomplete or univalent antibodies on the surface of the erythrocytes. (05 Mar 2000) |
| indirect Coombs' test | A test routinely performed in cross-matching blood or in the investigation of transfusion reaction: test for patient's serum is incubated with a suspension of donor erythrocytes; if specific antibodies are present, they become attached to the antigen in donor's cells; after a washing with saline, Coombs' antihuman globulin is added; agglutination at this point indicates that antibodies present in the original test serum had indeed become attached to donor erythrocytes. (05 Mar 2000) |
| amino acid reagent | A reagent used in the identification and quantification of amino acids. (05 Mar 2000) |
| Benedict-Hopkins-Cole reagent | <chemistry> Magnesium glyoxalate, made from a mixture of oxalic acid and magnesium, used for testing proteins for the presence of tryptophan. (12 Aug 2000) |
| biuret reagent | An alkaline solution of copper sulfate. (05 Mar 2000) |
| Mandelin's reagent | A solution of ammonium vanadate in sulfuric acid, used in colour tests for alkaloids. (05 Mar 2000) |
| reagent | <technique> A histochemical technique based on periodic acid oxidation of a substance containing the 1,2-glycol grouping. It is used for staining carbohydrates as the resulting dialdehyde reacts with Schiff reagent to form a coloured product. The adjacent hydroxyl groups are oxidized to form aldehydes by periodic acid (HIO4) and these aldehyde groups react with Schiff's reagent (basic fuchsin decolourised by sulphurous acid) to give a purple colour. Acronym: PAS (18 Nov 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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