| ¿µ¹® | recessive | ÇÑ±Û | ¿¼º |
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| ¼³¸í | ´ë¸³ÇüÁú Áß ÀâÁ¾ Á¦1´ë¿¡¼ ¼û¾î¼ ³ªÅ¸³ªÁö ¾Ê´Â ÇüÁú. ¿ì¼º¿¡ ´ëÀÀµÇ´Â ¸»ÀÌ´Ù. ³ªÅ¸³ª´Â ÂÊ¿¡ ´ëÇØ ¿¼ºÀ̶ó Çϰí, ±× ÇüÁúÀ» ¿¼ºÇüÁúÀ̶ó°í ÇÑ´Ù. Á¦2´ë(F2)¿¡¼´Â ¿¼ºÇüÁúÀº ºÐ¸®µÇ¾î 1/3ÀÇ ºñÀ²·Î ³ªÅ¸³´Ù. À¯ÀüÀû ´ë¸³ÇüÁú¿¡´Â ¿ì¼º°ú ¿¼ºÀÌ ÀÖ°í, À̰͵éÀº ¿ì¼ºÀ¯ÀüÀÚ¿Í ¿¼ºÀ¯ÀüÀÚ¿¡ ÀÇÇØ Áö¹èµÈ´Ù. ¿¹¸¦ µé¸é, ¾î¶² ¿ì¼ºÇüÁúÀ» Áö¹èÇÏ´Â À¯ÀüÀÚ¸¦ A¶ó Çϰí, ±×°Í¿¡ ´ëÀÀÇÏ´Â ¿¼ºÀ¯ÀüÀÚ¸¦ a¶ó°í Çϸé, ¿ì¼ºÀ¯ÀüÀÚ¸¦ °¡Áø ¾î¹öÀÌ(AA)¿Í ¿¼ºÀ¯ÀüÀÚ¸¦ °¡Áø ¾î¹öÀÌ(aa)ÀÇ ±³¹è¿¡ ÀÇÇÏ¿© »ý±ä ÀâÁ¾ Á¦1´ë(F1)´Â Aa°¡ µÇ¾î ¿ì¼ºÇüÁúÀ» ³ªÅ¸³½´Ù. Aa À¯ÀüÀÚ¸¦ °¡Áø F1³¢¸®¸¦ ±³¹èÇϸé ÀâÁ¾ Á¦2´ë(F2)¿¡¼´Â AA:Aa:aa°¡ 1:2:1ÀÇ ºñÀ²·Î ºÐ¸®µÇ¾î ¿¼ºÇüÁúÀº F2´ë¿¡ 1/3ÀÇ ºñÀ²·Î »ý±ä´Ù. ¿ì¼º-¿¼ºÀ̶õ ÇüÁúÀÇ °¡Ä¡ ¿ì¿À» ¸»ÇÏ´Â °ÍÀÌ ¾Æ´Ï´Ù. ¿¼ºÀÌ µÚ¶³¾îÁ³´Ù´Â ÀλóÀ» Áشٰí ÇÏ¿© ¿¼ºÀ» ÀἺÀ¸·Î, ¿ì¼ºÀ» Çö¼ºÀ¸·Î ÇÏÀÚ°í ÁÖÀåÇÏ´Â ÇÐÀÚµµ ÀÖ´Ù. |
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| AP | accessory pathway; accounts payable; acid phosphatase; acinar parenchyma; action potential; active p... |
|---|---|
| APC | acetylsalicylic acid, phenacetin, and caffeine; activated protein C; adenoidal-pharyngeal-conjunctiv... |
| FAP | familial adenomatous polyposis; familial amyloid polyneuropathy; fatty acid polyunsaturated; fatty a... |
| CC | calcaneal-cuboid; calcium cyclamate; cardiac catheterization; cardiac contusion; cardiac cycle; card... |
| CR | calculation rate; calculus removed; calorie-restricted; cardiac rehabilitation; cardiac resuscitatio... |
| APC | Adenomatous Polyposis Coli |
|---|---|
| APC | Adenomatous polyposis coli protein |
| FAP | Familial Adenomatous Polyposis |
| FAP | Familial adenomatous polyposis coli |
| APC | adenomatous polyposis coli gene |
| adenomatous polyposis coli | An autosomal dominant polyposis syndrome in which the colon contains few to thousands of adenomatous polyps, often occurring by age 15 to 25. (12 Dec 1998) |
|---|---|
| familial adenomatous polyposis | <gastroenterology> Genetic disease with numerous precancerous polyps in the colon and rectum. Also called familial polyposis. (12 Dec 1998) |
| colorectal | <anatomy> Pertaining to or affecting the colon and rectum. (18 Nov 1997) |
| colorectal cancer | <oncology> A malignancy that arises from the lining of either the colon or the rectum. Cancers of the large intestine are the second most common form of cancer found in males and females. Symptoms include rectal bleeding, occult blood in stools, bowel obstruction and weight loss. Treatment is based largely on the extent of cancer penetration into the intestinal wall. Surgical cures are possible if the malignancy is confined to the intestine. Risk can be reduced when following a diet which is low in fat and high in fibre. (27 Sep 1997) |
| colorectal surgeon | <specialist> A specialist that is expert in the surgical care of colorectal disease (for example haemorrhoids, cancer). (11 Mar 1998) |
| adenomatous | Relating to an adenoma, and to some types of glandular hyperplasia. (05 Mar 2000) |
| adenomatous colon polyps | <radiology> Probability of malignancy by size and type Size (cm) less than 1 1-2 greater than 2 --------------------------- tubular 1% 10% 34% mixed (TV) 4% 9% 45% villous 10% 10% 54%, most colon polyps (90%) are hyperplastic (size less than 5 mm) (12 Dec 1998) |
| adenomatous goiter | An enlargement of the thyroid gland due to the growth of one or more encapsulated adenomas or multiple nonencapsulated colloid nodules within its substance. (05 Mar 2000) |
| adenomatous polyp | A polyp that consists of benign neoplastic tissue derived from glandular epithelium. Synonym: cellular polyp, polypoid adenoma. (05 Mar 2000) |
| adenomatous polyps | Benign neoplasms derived from glandular epithelium. (12 Dec 1998) |
| autosomal recessive | <genetics> Mutation carried on an autosome that is deleterious only in homozygotes. (02 Jan 1998) |
| genes, recessive | Genes that are reflected in the phenotype only in the homozygous state. (12 Dec 1998) |
| recessive | <genetics> An allele or mutation that is only expressed phenotypically when it is present in the homozygous form. In the heterozygote it is obscured by dominant alleles. (18 Nov 1997) |
| recessive, autosomal | A gene on a nonsex chromosome (an autosome) that expresses itself only when there is no different gene present at that locus (spot on the chromosome). For example, cystic fibrosis (cf) is an autosomal recessive disorder. A cf child has the cf gene on both chromosome 7's (and so is said to be homozygous for cf). (12 Dec 1998) |
| recessive character | An inherited character determined by an allele in homozygous state only. See: dominance of traits. (05 Mar 2000) |
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