| ung. | unguentum; ointment; ¿¬°í |
|---|---|
| CDP | chondrodysplasia punctata; chronic destructive periodontitis; collagenase-digestible protein; contin... |
| CSGBM | collagenase soluble glomerular basement membrane |
| HCI | Health Commons Institute; human collagenase inhibitor |
| HPO | high-presure oxygen; hydroperoxide; hydrophilic ointment; hypertrophic pulmonary osteoarthropathy |
| CDP | collagenase digestible protein |
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oleagenous ointment
| microbial collagenase | <enzyme> A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -gly in the sequence -pro-xaa-gly-pro-. Six forms (or 2 classes) have been isolated from clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from bacillus cereus, empedobacter collagenolyticum, pseudomonas marinoglutinosa, and species of vibrio and streptomyces. Registry number: EC 3.4.24.3 (12 Dec 1998) |
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| Clostridium histolyticum collagenase | <enzyme> An enzyme that catalyses the hydrolysis of collagen, preferentially at peptide bonds on the amino side of a glycylprolyl sequence. Synonym: clostridiopeptidase A, collagenase A, collagenase I. (05 Mar 2000) |
| collagenase | <enzyme> Proteolytic enzyme capable of breaking native collagen. Once the initial cleavage is made, less specific proteases will complete the degradation. Collagenases from mammalian cells are metallo enzymes and are collagen type specific. May be released in latent (proenzyme) form into tissues and require activation by other proteases before they will degrade fibrillar matrix. Bacterial collagenases are used in tissue disruption for cell harvesting. (18 Nov 1997) |
| collagenase A | <enzyme> An enzyme that catalyses the hydrolysis of collagen, preferentially at peptide bonds on the amino side of a glycylprolyl sequence. Synonym: clostridiopeptidase A, collagenase A, collagenase I. (05 Mar 2000) |
| neutrophil collagenase | <enzyme> Cleaves interstitial collagens in the triple helical domain; cleaves type I collagen more rapidly than type III; fibroblast collagenase cleaves at the same site as neutrophil colagenase Registry number: EC 3.4.24.34 Synonym: matrix metalloproteinase 8, mmp-8, mmp 8, fibroblast collagenase (26 Jun 1999) |
| antibacterial ointment | A ointment (or cream) based medication that kills bacteria. Examples include Neosporin, Bactroban, Garamycin, bacitracin, gentamicin, mupirocin, neomycin, silver sulphasalazine, chloramphenicol and clindamycin. (27 Sep 1997) |
| antibiotic ointment | A ointment (or cream) based medication that kills bacteria. Examples include Neosporin, Bactroban, Garamycin, bacitracin, gentamicin, mupirocin, neomycin, silver sulphasalazine, chloramphenicol and clindamycin. (27 Sep 1997) |
| blue ointment | A grease-based ointment containing 20% finely divided metallic mercury, formerly widely used for local application to the skin for the destruction of body lice. Risk is associated with transdermal absorption of mercury and a local dermatitis. Synonym: mild mercurial ointment. (05 Mar 2000) |
| mild mercurial ointment | A grease-based ointment containing 20% finely divided metallic mercury, formerly widely used for local application to the skin for the destruction of body lice. Risk is associated with transdermal absorption of mercury and a local dermatitis. Synonym: mild mercurial ointment. (05 Mar 2000) |
| hydrophilic ointment | An ointment base consisting of 25% each of white petrolatum and stearyl alcohol, 12% propyl glycol emulsified in 37% water by 1% of lauryl sulfate; preserved with paraben. Suitable for the incorporation of numerous drugs intended for local application; a washable ointment base. (05 Mar 2000) |
| ointment | An ointment has an oil base whereas a cream is water-soluble. (the word ointment comes from the latin ungere meaning anoint with oil). (12 Dec 1998) |
| ointment base | The vehicle into which active ingredients may be incorporated. Petrolatum (which may be stiffened with wax) is the most widely used greasy ointment base and is suitable for the incorporation of oleaginous materials. Lin-containing bases will absorb water (and dissolved materials) and form water-in-oil type emulsions. Water soluble (washable) bases are often derived from polymers of ethylene glycol (PEGS); these will absorb water and ingredients dissolved in the water. Ointment bases are usually pharmacologically inert but may entrap water and serve to keep the skin from dying or to provide an emollient protective film. (05 Mar 2000) |
| ointment bases | Various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons; vehicles for medicinal substances intended for external application; there are four classes: hydrocarbon base, absorption base, water-removable base and water-soluble base; several are also emollients. (12 Dec 1998) |
| ophthalmic ointment | A special ointment for application to the eye that must be free from particles and must be nonirritating to the eye. Synonym: eye ointment, oculentum. (05 Mar 2000) |
| eye ointment | A special ointment for application to the eye that must be free from particles and must be nonirritating to the eye. Synonym: eye ointment, oculentum. (05 Mar 2000) |
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