| chymopapain | <enzyme> A peptide peptidohydrolase with cysteine at the active centre from papaya. Preferential cleavage at glutamic and aspartic acid residues. Also catalyses the synthesis of hippuryl-aniline. Registry number: EC 3.4.22.6 (12 Dec 1998) |
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Synonyms : Chemolase, Chymodiactin, Chymopapain A, Chymopapain B, Discase, Farmamed Brand of Chymopapain, Link Brand of Chymopapain
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| chymopapain |
[EC 3.4.22.6] an enzyme of the hydrolase class, a cysteine endopeptidase, that catalyzes the hydrolysis of proteins and polypeptides. Its specificity is very close to that of papain and both occur in the latex of the tropical papaya tree, Carica papaya. The enzyme is used to break down the proteoglycan portion of the nucleus pulposus in the treatment of herniation of intervertebral (lumbar) disks by chemonucleolysis.
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