| ¿µ¹® | osmotic fragility | ÇÑ±Û | »ïÅõ¾ÐÃë¾à¼º |
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| ¼³¸í | ÀûÇ÷±¸¼¼Æ÷ÀÇ »ïÅõ¾Ð Ư¼º º¯È¿¡ ´ëÇÑ ¹Î°¨¼º. ÀûÇ÷±¸°¡ Àú³óµµÀÇ ³ªÆ®·ý ¿ë¾×¿¡ ³ëÃâÇÏ¸é ¼¼Æ÷¸·ÀÇ ´É·ÂÀ» ÃʰúÇÒ ¶§±îÁö ´Ù·®ÀÇ ¹°À» Èí¼öÇÏ¿© ºÎÇ®¾î¿Ã¶ó ÆÄ¿ÇÏ°í °í³óµµÀÇ ³ªÆ®·ý ¿ë¾×¿¡ ³ëÃâÇϸé ÀûÇ÷±¸ÀÇ ¼¼Æ÷³»¾×ÀÌ ºüÁ®³ª°¡ Å©±â°¡ ÁÙ¾îµé¸ç ÆÄ±«µÈ´Ù. ¿¹¿ÜÀû Ãë¾à¼ºÀ̳ª ÀúÇ×¼ºÀº ƯÁ¤ º´ÀÇ Áø´ÜÀû ±âÁØÀÌ µÉ¼ö ÀÖ´Ù. Á¤»ó¼¼Æ÷´Â 0.39~0.45% ¼Ò±Ý¹° ¿ë¾×¿¡¼ ¿ëÇ÷ÀÌ ½ÃÀ۵Ǹç, 37¡É(98.6¢µ)¿¡¼ 0.30~0.33% ¼Ò±Ý ¿ë¾×¿¡ ÀûÇ÷±¸¸¦ ³ëÃâ½ÃŰ¸é ¿ëÇ÷Àº 24½Ã°£ À̳»¿¡ ¿Ï·áµÈ´Ù. |
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| ¿µ¹® | sex chromosome | ÇÑ±Û | ¼º¿°»öü |
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| ¼³¸í | ¾Ï¼öÀÇ ¼ºÀ» °áÁ¤ÇÏ´Â µ¥ Áß¿äÇÑ ±¸½ÇÀ» ÇÏ´Â ¿°»öü. À̰Ϳ¡ ´ëÇÏ¿© º¸ÅëÀÇ ¿°»öü¸¦ º¸Åë¿°»öü¶ó°í ÇÑ´Ù. ¾Ï¼öÀÇ ±¸º°ÀÌ ÀÖ´Â »ý¹°¿¡¼´Â ¾Ï¼ö¿¡ µû¶ó ´Ù¸¥ Çü°ú ¼ö¸¦ ³ªÅ¸³»´Â ¿°»öüÀ̸ç, º¸Åë¿°»öü¿¡ ºñÇØ ¿°»ö¼ºÀ̳ª Çൿ¿¡¼ Â÷À̰¡ ÀÖ´Ù. ƯÈ÷ µ¿¹°ÀÇ ¼º¿°»öü´Â ±×·± °æÇâÀÌ °ÇÏ´Ù. ÈÞÁö±â ¹× Çٺп Àü±â¿¡ ¶Ñ·ÇÇÑ ÀÌ»óÀÀÃàÀ» ³ªÅ¸³»¸ç °¨¼öºÐ¿ ¶§´Â ´Ù¸¥ ¿°»öüº¸´Ù ¸ÕÀú ¾Õ¼°Å³ª ²ø·Á°¡´Â ÇൿÀ» º¸¿©ÁØ´Ù. |
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| ¿µ¹® | chromosome | ÇÑ±Û | ¿°»öü |
|---|---|---|---|
| ¼³¸í | À¯ÀüÁ¤º¸¸¦ ´ã°í ÀÖ´Â DNA°¡ ¸ð¿©¼ ÀÌ·ç´Â ±¸Á¶¹°·Î ÇÙ¼Ó¿¡ À§Ä¡ÇÑ´Ù. ¼¼Æ÷°¡ ºÐ¿ÇÒ ¶§ À̰ÍÀ» ´õ¿í ¶Ñ·ÇÀÌ °üÂûÇÒ ¼ö°¡ ÀÖ´Ù. À̰ÍÀº »ç¶÷ó·³ °íµî»ý¹°Ã¼¿¡¼ ³Ê¹«³ª ¸¹Àº Á¤º¸¸¦ ´ã°í ÀÖ¾î, ¾öû³ ±æÀÌ(»ç¶÷¿¡ ÀÖ¾î¼ Àü DNA¸¦ ±æÀÌ·Î µûÁö¸é ¾à 2m°¡ µÈ´Ù)°¡ µÈ DNA¸¦ ÀÛÀº ÇÙÀ̶õ °ø°£¼Ó¿¡ º¸°üÇϱâ À§Çؼ ¸¸µé¾îÁø ±¸Á¶ÀÌ´Ù. ÀÌ ¿°»öüÀÇ ¼ö´Â »ý¹°ÀÇ Á¾¿¡ µû¶ó ´Ù¸£¸ç »ç¶÷ÀÇ °æ¿ì´Â 46°³ÀÌ´Ù. |
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| ¿µ¹® | chromosome abnormality | ÇÑ±Û | ¿°»öüÀÌ»ó |
|---|---|---|---|
| ¼³¸í | ¿°»öüÀÇ ¼ö³ª ±¸Á¶ÀÇ ÀÌ»ó. ÀÌ»óÀÌ »ý±ä ¼¼Æ÷³ª °³Ã¼´Â À¯ÀüÀûÀÎ ÀÌ»óÀ» ÀÏÀ¸ÄÑ »ç¶÷ÀÇ °æ¿ì, ´Ù¿î ÁõÈıº-ÅÍ³Ê ÁõÈıº µûÀ§ÀÇ ¿©·¯ °¡Áö ÇüÅ·Π³ªÅ¸³´Ù. |
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| Xp | paternal chromosome X; short arm of chromosome X |
|---|---|
| HCF | [fetal] head-to-cervix force; heparin cofactor; hereditary capillary fragility; highest common facto... |
| MCF | macrophage chemotactic factor; median cleft face; medium corpuscular fragility; microcomplement fixa... |
| OF | occipitofrontal; open field [test]; optical fundus; orbitofrontal; osmotic fragility; osteitis fibro... |
| VFS | vascular fragility syndrome |
| BAC | Bacterial Artificial Chromosome |
|---|---|
| CHr | Chromosome |
| CA | Chromosome aberration |
| CMGT | Chromosome mediated gene transfer |
| CCR | Complex chromosome rearrangements |
| capillary fragility | The lack of resistance, or susceptibility, of capillaries to damage or disruption under conditions of increased stress. (12 Dec 1998) |
|---|---|
| capillary fragility test | A tourniquet test used to determine presence of vitamin C deficiency or thrombocytopenia; a circle 2.5 cm in diameter, the upper edge of which is 4 cm below the crease of the elbow, is drawn on the inner aspect of the forearm, pressure midway between the systolic and diastolic blood pressure is applied above the elbow for 15 minutes, and a count of petechiae within the circle is made: 10, normal; 10 to 20, marginal zone; over 20, abnormal. See: Rumpel-Leede test. Synonym: capillary resistance test, vitamin C test. (05 Mar 2000) |
| osmotic fragility | The susceptibility, or lack of resistance, of erythrocytes to haemolysis when exposed to increasingly hypotonic saline solutions. (12 Dec 1998) |
| fragility | Brittleness; liability to break, burst, or disintegrate. Synonym: fragilitas. Origin: L. Fragilitas (05 Mar 2000) |
| fragility of the blood | The susceptibility, or lack of resistance, of erythrocytes to haemolysis when exposed to increasingly hypotonic saline solutions. (12 Dec 1998) |
| fragility test | A test that measures the resistance of erythrocytes to haemolysis in hypotonic saline solutions; erythrocytes to be tested are added to varying concentrations of saline (usually ranging from 0.85 to 0.10% sodium chloride with 0.05% increments), and beginning and complete haemolysis are measured; normal erythrocytes show initial haemolysis at concentrations of 0.45 to 0.39% and complete haemolysis at 0.33 to 0.30%; in hereditary spherocytosis the fragility of the erythrocytes is markedly increased, whereas in thalassaemia, sickle cell anaemia, and obstructive jaundice the fragility of the erythrocytes is usually reduced. Synonym: erythrocyte fragility test. (05 Mar 2000) |
| accessory chromosome | A chromosome existing without its normal homologous chromosome; at the reduction division of gametogenesis an accessory chromosome is likely to be included in one daughter cell and not in the other, but may be lost completely by lagging behind on the equatorial plate. Synonym: monosome, odd chromosome, unpaired allosome, unpaired chromosome. (05 Mar 2000) |
| acentric chromosome | A fragment of a chromosome lacking a centromere and unable to attach to the mitotic spindle, therefore unable to take part in the division of a nucleus and randomly distributed in daughter cells. Synonym: acentric fragment. (05 Mar 2000) |
| acrocentric chromosome | A chromosome with the centromere placed very close to one end so that the short arm is very small, often with a satellite. (05 Mar 2000) |
| balanced chromosome | <genetics> A chromosome which is unable to pair with its homologue and participate in homologus recombination during meiosis because it contains several inversion mutations (that is, has segments which have become flip-flopped). (09 Oct 1997) |
| B chromosome | <genetics> Small acentric chromosome, part of the normal genome of some races and species of plants. (18 Nov 1997) |
| bivalent chromosome | A pair of chromosome's temporarily united. (05 Mar 2000) |
| male chromosome complement | The large majority of males have a 46, xy chromosome complement (46 chromosomes including an x and a y chromosome). A minority of males have other chromosome constitutions such as 47,xxy (47 chromosomes including two x chromosomes and a y chromosome) and 47,xyy (47 chromosomes including an x and two y chromosomes). (12 Dec 1998) |
| marker chromosome | An abnormal chromosome that is distinctive in appearance but not fully identified. For example, the fragile x chromosome was once called the marker x. (12 Dec 1998) |
| p arm of a chromosome | The short arm of a chromosome (from the french petit meaning small). All human chromosomes have 2 arms: the p and q arms. (12 Dec 1998) |
Synonyms : Chromosomal Fragility, Fragility, Chromosomal, Fragility, Chromosome
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