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CAP camptodactyly-arthropathy-pericarditis [syndrome]; Canada Assistance Plan; capsule; captopril; catab...
CAT California Achievement Test; capillary agglutination test; catalase; cataract; catecholamine; Childr...
CHL Chinese hamster lung; chlorambucil; chloramphenicol
CMC carboxymethylcellulose; care management continuity; carpometacarpal; cell-mediated cytolysis or cyto...
CSMP chloramphenicol-sensitive microsomal protein
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CAM Chloramphenicol
CAP Chloramphenicol
CM Chloramphenicol
CP Chloramphenicol
CmR Chloramphenicol resistance
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chloramphenicol <drug> A broad-spectrum antibiotic that inhibits bacterial protein synthesis in prokaryotes and in mitochondria and chloroplasts by acting on the 50S ribosomal subunit.
It was first isolated from the fungus like bacterium Streptomyces venezuelae but is now produced synthetically. It is relatively toxic but finds wide application in medicine.
(01 Dec 1998)
chloramphenicol 3'-O-phosphotransferase <enzyme> Phosphorylates the 3'-oh position of chloramphenicol producing a metabolite which confers resistance to chloramphenicol when introduced into a chloramphenicol-sensitive host
Registry number: EC 2.7.1.-
Synonym: cpt protein, cpt gene product
(26 Jun 1999)
chloramphenicol acetyltransferase <enzyme> A bacterial enzyme that inactivates the antibiotic chloramphenicol by acetylation. Widely used as a reporter gene for examining the control of eucaryotic gene expression.
Acronym: CAT
(08 Mar 2000)
chloramphenicol acetyltransferase assay <investigation> A lab technique used to determine whether a given fragment of DNA has a promoter on it to encourage transcription to occur, by attaching the gene (called the CAT gene) which codes for the CAT enzyme to it, and observing whether the CAT enzyme is produced.
(05 Jan 1998)
chloramphenicol acetyltransferase gene <molecular biology> A gene which codes for the CAT enzyme (the enzyme chloramphenicol acetyltransferase), which helps transfer an acetyl group (a CH3CO- group) to chloramphenicol, an antibiotic. The CAT gene is an important part of CAT assays.
(09 Oct 1997)
chloramphenicol amidase <enzyme> Mouse liver microsomal enzyme which cleaves dichloro-acetyl group from chloramphenicol
Registry number: EC 3.5.1.-
Synonym: chloramphenicol hydrolase.
(26 Jun 1999)
chloramphenicol o-acetyltransferase <enzyme> An enzyme that catalyses the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria.
Chemical name: Acetyl-CoA-chloramphenicol 3-O-acetyltransferase
Registry number: EC 2.3.1.28
(12 Dec 1998)
chloramphenicol palmitate <chemical> Same action and use as chloramphenicol.
(05 Mar 2000)
chloramphenicol resistance <microbiology, pharmacology> Nonsusceptibility of a bacterium to the action of chloramphenicol, a potent inhibitor of protein synthesis in the 50s ribosomal subunit where amino acids are added to nascent bacterial polypeptides.
(12 Dec 1998)
chloramphenicol sodium succinate <chemical> Chloramphenicol-alpha-(sodium succinate);the water-soluble sodium succinate derivative of chloramphenicol, suitable for parenteral administration; antibacterial activity, uses, and side effects are similar to those of the parent compound.
(05 Mar 2000)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 3 ÆäÀÌÁö: 1
  • Chloramphenicol - »õâ An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
    Synonyms : Chlornitromycin, Chlorocid, Chloromycetin, Detreomycin, Ophthochlor, Syntomycin
  • Chloramphenicol O-Acetyltransferase - »õâ An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 2.3.1.28.
    Synonyms : Chloramphenicol Transacetylase, Acetyltransferase, Chloramphenicol, Chloramphenicol O Acetyltransferase, Enzyme, CAT, O-Acetyltransferase, Chloramphenicol, Transacetylase, Chloramphenicol
  • Chloramphenicol Resistance - »õâ Nonsusceptibility of bacteria to the action of CHLORAMPHENICOL, a potent inhibitor of protein synthesis in the 50S ribosomal subunit where amino acids are added to nascent bacterial polypeptides.
    Synonyms : Chloramphenicol Resistances
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  • Chloramphenicol - serum - »õâ
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A50700731 Chloramphenicol, Dexamethasone disodium phosphate, Tetrahydrozoline HCl
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A08402501 Chloramphenicol, Dexamethasone disodium phosphate, Tetrahydrozoline HCl
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chloramphenicol palmitate [USP] the monopalmitic ester of chloramphenicol, having the same actions and uses as the base; administered orally.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
chloramphenicol sodium succinate [USP] the sodium succinate derivative of chloramphenicol, having the same actions and uses as the base; administered intravenously. Sterile chloramphenicol sodium succinate [USP] conforms to FDA regulations concerning antibiotic drugs.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
chloramphenicol palmitate Chloramphenicol is an antibiotic that was derived from the bacterium Streptomyces venezuelae and is now produced synthetically. Chloramphenicol is effective against a wide variety of microorganisms, but due to serious side-effects (e.g., damage to the bone marrow, including aplastic anemia) in humans, it is usually reserved for the treatment of serious and life-threatening infections (e.g., typhoid fever). ...
Ãâó: en.wikipedia.org/wiki/Chloramphenicol_palmitate
chloramphenicol sodium succinate Chloramphenicol is an antibiotic that was derived from the bacterium Streptomyces venezuelae and is now produced synthetically. Chloramphenicol is effective against a wide variety of microorganisms, but due to serious side-effects (e.g., damage to the bone marrow, including aplastic anemia) in humans, it is usually reserved for the treatment of serious and life-threatening infections (e.g., typhoid fever). ...
Ãâó: en.wikipedia.org/wiki/Chloramphenicol_sodium_succi...
chloramphenicol [USP] a broad-spectrum antibiotic, originally derived from Streptomyces venezuelae and later shown to be elaborated by other spirochetes, and produced synthetically. It is effective against rickettsiae, gram-positive and gram-negative bacteria, and certain spirochetes, being used especially in the treatment of typhus and other rickettsial infections and in typhoid, shigellosis, and related enteric diseases; used as an antibacterial, administered orally or applied topically to the conjunctiva or ear, or as an antirickettsial, administered orally.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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Chloramphenicol an oral antibiotic (trade name Chloromycetin) used to treat serious infections (especially typhoid fever)
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