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"Canavan's sclerosis"¿¡ ´ëÇÑ °Ë»ö °á°úÀÔ´Ï´Ù. °Ë»ö °á°ú º¸´Â µµÁß¿¡ Tab ۸¦ ´©¸£½Ã¸é °Ë»ö âÀÌ ¼±Åõ˴ϴÙ.
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¿µ¹® sclerosis ÇÑ±Û °æÈ­(Áõ), ±»À½(Áõ)
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¿µ¹® amyotrophic laternal sclerosis ÇÑ±Û ±ÙÀ§ÃàÃø»è°æÈ­Áß
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  »ç¶÷ÀÌ ±ÙÀ° Çϳª¸¦ ¿òÁ÷À϶§ »ç¿ëÇϴ ½Å°æ¿¬°áÀ» »ìÆìº¸¸é ´ÙÀ½°ú °°´Ù. ¿ì¼± ´ë³ú¿¡ Àִ ¿îµ¿À» °üÀåÇϴ °÷ÀΠ¿îµ¿°ÑÁú¿¡¼­ÀÇ ¸í·ÉÀÌ ¶³¾îÁö¸é À̰ÍÀº Ã´¼ö¸¦ Å¸°í °è¼ÓÇØ¼­ ³»·Á¿À°Ô µÈ´Ù. ±×¸®°í Ã´¼ö¿¡¼­ Çѹø ½Å°æ¼¼Æ÷¸¦ ¹Ù²Ù¾î¼­ ¸»ÃʽŰ栱ÙÀ°¿¡ °¡¼­ ±ÙÀ°À» ¿òÁ÷ÀδÙ. Áï ´ë³ú¿¡¼­ ¶³¾îÁø ¸í·ÉÀÌ ½Å°æ¼¼Æ÷ Çϳª¸¦ Å¸°í Ã´¼ö±îÁö °¡°í Ã´¼ö¿¡¼­ ÇÑ ¹ø ½Å°æÀ» ¹Ù²Ù¾î ±ÙÀ°À¸·Î °£´Ù.
  
  Ã´¼ö¿¡¼­ ½ÃÀÛÇÏ¿© ±ÙÀ°±îÁö °¡´Â ½Å°æ ¼¼Æ÷¸¦ ¾Õ»Ô¼¼Æ÷¶ó°í ÇÑ´Ù. ¿øÀΠ¹Ì»óÀΠÀÌ º´Àº ¾Õ»Ô¼¼Æ÷ÀÇ ¼Ò½Ç¿¡ ÀÇÇØ¼­ ±×°ÍÀÇ Áö¹è¸¦ ¹Þ´Â ±ÙÀ°ÀÇ À§ÃàÀÌ ³ªÅ¸³ª´Â °ÍÀ» ÁÖÁõ»óÀ¸·Î ÇÑ´Ù. ÀÌ º´¿¡ Æ¯È¿°¡ Àִ ġ·á¹ýÀº ¾ÆÁ÷ ¾ø´Ù.
¿µ¹® multiple sclerosis ÇÑ±Û ´Ù¹ß°æÈ­Áõ
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  ½Å°æÃà»èÀ» µÑ·¯½Î°í Àִ ¸»ÀÌÁý(myelin sheath)ÀÇ ÆÄ±«·Î ÀÎÇÑ º´Àû»óŸ¦ ¸»ÇÔ. ÆÄ±«µÈ ¸»ÀÌÁýÀº ÈäÅ͸¦ ³²±â°Ô µÇ¾î ½Å°æÃà»èÀ» ÅëÇÑ ½Å°æÀü´ÞÀÌ Á¦´ë·Î µÇÁö ¾Ê¾Æ ¿îµ¿, °¨°¢, ÀÚÀ²½Å°æ ¸ðµÎÀÇ ½Å°æÀü´ÞÀå¾Ö°¡ ³ªÅ¸³­´Ù. ÀÌ º´Åʹ ¾îµð¼­³ª ³ªÅ¸³¯ ¼ö À־ ±× Àå¾Ö°¡ ³ªÅ¸³ª´Â ºÎÀ§¿¡ µû¶ó ¼­·Î ´Ù¸¥ Áõ»óÀ» È£¼ÒÇÑ´Ù.
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  • ¿µ¹®
    ÇѱÛ
  • Canavan disease
    ij³Ê¹øº´
  • annular sclerosis
    °í¸®°æÈ­, ȯ»ó°æÈ­
  • areolar choroidal sclerosis
    ¿øÇü¸Æ¶ô¸·°æÈ­(Áõ)
  • arteriolar sclerosis
    ¼¼µ¿¸Æ°æÈ­(Áõ)
  • amyotrophic lateral sclerosis
    ±ÙÀ°À§Ãà°¡ÂʰæÈ­(Áõ), ±ÙÀ§ÃàÃø»è°æÈ­(Áõ)
  • bulbar sclerosis
    ¼û³ú°æÈ­(Áõ), ¿¬¼ö°æÈ­(Áõ)
  • combined sclerosis
    ¿¬ÇÕ°æÈ­Áõ
  • coronary sclerosis
    °ü»óµ¿¸Æ°æÈ­Áõ, ½ÉÀ嵿¸Æ°æÈ­Áõ
  • calcific sclerosis
    ¼®È¸°æÈ­
  • choroidal sclerosis
    ¸Æ¶ô¸·°æÈ­Áõ
  • degenerative diffuse cerebral sclerosis
    ÅðÇ౤¹üÀ§´ë³ú°æÈ­(Áõ)
  • diffuse cerebral sclerosis
    ±¤¹üÀ§´ë³ú°æÈ­Áõ
  • diffuse sclerosis
    ±¤¹üÀ§°æÈ­Áõ
  • diffuse systemic sclerosis
    ±¤¹üÀ§Àü½Å°æÈ­Áõ
  • disseminated sclerosis
    ÆÄÁ¾°æÈ­Áõ
´ëÇÑÀÇÇù Çʼö ÀÇÇпë¾îÁý »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 4 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • sclerosis
    °æÈ­(Áõ), ±»À½(Áõ)
  • amyotrophic lateral sclerosis
    ±ÙÀ°À§Ãà°¡ÂʰæÈ­Áõ
  • multiple sclerosis
    ´Ù¹ß°æÈ­Áõ
  • systemic sclerosis
    Àü½Å°æÈ­Áõ
¿¾ ´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • amyotrophic lateral sclerosis
    ±ÙÀ°À§Ãà°¡ÂʰæÈ­Áõ
  • annular sclerosis
    °í¸®°æÈ­Áõ
  • areolar choroidal sclerosis
    ¿øÇü¸Æ¶ô¸·°æÈ­(Áõ)
  • arteriolar sclerosis
    (¢¡arteriolosclerosis) ¼¼µ¿¸Æ°æÈ­Áõ
  • bulbar sclerosis
    ¿¬¼ö°æÈ­Áõ, ¼û³ú°æÈ­Áõ
  • calcific sclerosis
    ¼®È¸°æÈ­Áõ
  • choroidal sclerosis
    ¸Æ¶ô¸·°æÈ­(Áõ)
  • combined sclerosis
    (¢¡subacute combined degeneration) ¾Æ±Þ¼º¿¬ÇÕº¯¼º
  • coronary sclerosis
    ½ÉÀ嵿¸Æ°æÈ­Áõ, °ü»óµ¿¸Æ°æÈ­Áõ
  • degenerative diffuse cerebral sclerosis
    ÅðÇ౤¹üÀ§³ú°æÈ­(Áõ)
  • diffuse sclerosis
    ±¤¹üÀ§°æÈ­Áõ
  • diffuse cerebral sclerosis
    ±¤¹üÀ§³ú°æÈ­Áõ
  • diffuse systemic sclerosis
    ±¤¹üÀ§Àü½Å°æÈ­Áõ
  • disseminated sclerosis
    (¢¡multiple sclerosis) ´Ù¹ß°æÈ­Áõ
  • endocardial sclerosis
    ½ÉÀå³»¸·°æÈ­Áõ
¿¾ ´ëÇÑÀÇÇù 2 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • Bournevilles disease->tuberous sclerosis
    ºÎ¸£³×ºôº´
  • amyotrophic lateral sclerosis
    ±ÙÀ§Ã༺ Ãø»è °æÈ­Áõ(¡­ö°ßãÌãûùñø).
  • amyotrophic lateral sclerosis
    ±ÙÀ§Ãà¼ºÃø»è°æÈ­Áõ(ÐÉê×õêàõö°ÞþÌãûùñø)
  • annular sclerosis
    À±»ó°æÈ­Áõ(¡­Ìãûùñø).
  • anterior spinal sclerosis
    Àü»è°æÈ­Áõ(îñßãÌãûùñø).
  • aortic sclerosis
    ´ëµ¿¸Æ°æÈ­(Áõ)(¡­Ìãûùñø).
  • areolar choroidal sclerosis
    ¿øÇü¸Æ¶ô¸·°æÈ­(Áõ)
  • funicular sclerosis
    »è»ó°æÈ­(Áõ).
  • hepatoportal sclerosis
    °£¹®¸Æ°æÈ­Áõ.
  • hereditary cerebellar sclerosis
    À¯Àü¼º ¼Ò³ú°æÈ­Áõ.
  • hereditary spinal sclerosis
    À¯Àü¼º ô¼ö °æÈ­Áõ(¡­Ìãûùñø).
  • hereditary spinal sclerosis
    À¯Àü¼º ô¼ö°æÈ­Áõ(¡­Ìãûùñø).
  • hodgkins disease,nodular sclerosis
    °áÀý¼º °æÈ­¼º
  • pigmentary sclerosis
    »ö¼Ò°æÈ­Áõ(ßäáÈàõ)
  • posterior spinal sclerosis
    ÈÄô¼ö°æÈ­Áõ (¡­Ìãûùñø).
¿¾ ´ëÇÑÀÇÇù 3 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • canavans disease
    Ä«³ª¹Ý º´ (¡­Ü»)
  • amyotrophic lateral sclerosis
    ±ÙÀ§Ã༺ Ãø»è °æÈ­Áõ(¡­ö°ßãÌãûùñø).
  • amyotrophic lateral sclerosis
    ±ÙÀ§Ãà¼ºÃø»è°æÈ­Áõ(ÐÉê×õêàõö°ÞþÌãûùñø)
  • annular sclerosis
    À±»ó°æÈ­Áõ(¡­Ìãûùñø).
  • anterior spinal sclerosis
    Àü»è°æÈ­Áõ(îñßãÌãûùñø).
  • aortic sclerosis
    ´ëµ¿¸Æ°æÈ­(Áõ)(¡­Ìãûùñø).
  • areolar choroidal sclerosis
    ¿øÇü¸Æ¶ô¸·°æÈ­(Áõ)
  • arteriolar sclerosis
    ¼¼µ¿¸Æ¼º °æÈ­Áõ.
  • bulbar sclerosis
    ±¸<¿¬¼ö>°æÈ­Áõ(Ϲ<æÅâÐ>Ìãûùñø).
  • calcific sclerosis
    ¼®È¸¼º°æÈ­Áõ(à´üéàõÌãûùñø).
  • calcific sclerosis
    ¼®È¸È­°æÈ­Áõ(¡­Ìãûùñø)
  • cardiac sclerosis
    ½ÉÀμº °æÈ­Áõ (ãýì×àõÌãûùñø)
  • cardiac sclerosis,hepatic
    °£ °æÈ­Áõ(ÊÜÌãûùñø)
  • choroidal sclerosis
    ¸Æ¶ô¸·°æÈ­(Áõ)
  • combined sclerosis
    º´ÇÕ°æÈ­Áõ(ܱùê Ìãûùñø).
KI ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 4 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • amyotrophic lateral sclerosis
    ±ÙÀ§Ãà¼ºÃø»è°æÈ­Áõ
  • multiple sclerosis
    ´Ù¹ß¼º°æÈ­Áõ
  • posterolateral sclerosis
    ÈÄ»èÃø»è°æÈ­Áõ
  • tuberous sclerosis
    °áÀý¼º°æÈ­Áõ
KMLE ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
ALS acute lateral sclerosis; advanced life support; afferent loop syndrome; amyotrophic lateral sclerosi...
NS natural science; Neosporin; nephrosclerosis; nephrotic syndrome; nervous system; neurological surger...
TSC technetium sulfur colloid; thiosemicarbazide; transverse spinal sclerosis; tuberous sclerosis
ALS Amyotrophic Lateral Sclerosis
ASO   1) Arterio-Sclerosis Obliterans
  2) Anti-Streptolysin O; - 166
KMLE ÀÚµ¿ÃßÃâ ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
CD Canavan disease
AHS Ammon's horn sclerosis
ALS amylotrophic lateral sclerosis
DMS Diffuse mesangial sclerosis
FALS Familial Amyotrophic Lateral Sclerosis
°æºÏ´ë Ä¡°ú´ëÇÐ ±¸°­³»°ú ±³½Ç »çÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
    ¼³¸í
  • Canavan's disease
    Ä«³ª¹Ý º´
    »ó¿°»öü ¿­¼º À¯ÀüÇÏ´Â ÁúȯÀ¸·Î ¾Æ½ºÆÄ¸£Å侯½Ç¶óÁ¦
  • amyotrophic lateral sclerosis
    ±ÙÀ§Ã༺ Ãø»è °æÈ­Áõ, ±ÙÀ§Ã༺ Ãø¹æ °æÈ­
    1. Ãßü·ÎÀÇ ´º·Ð ¹× ³ú°£°ú ô¼öÀÇ ¿îµ¿¼¼Æ÷ÀÇ ÁøÇ༺ÀÎ º¯¼ºÀ» Ư¡À¸·Î ÇÏ´Â ÁúȯÀ¸·Î¼­, »óÀ§ ¹× ÇÏÀ§ÀÇ ¿îµ¿½Å°æÀÇ °á¼ÕÀ» ÃÊ·¡ÇÑ´Ù. º¸Åë 2-3³â³»¿¡ »ç¸ÁÇÑ´Ù. 2. »óÀ§ 1Â÷ ¿îµ¿ ´º·Ð°ú ÇÏÀ§ 2Â÷ ¿îµ¿ ´º·ÐÀÌ ÇÔ²² ħ¹üµÇ´Â ¿øÀÎ ºÒ¸íÀÇ °èÅ뼺 ÁúȯÀ¸·Î 30-50¼¼ÀÇ ³²¼º¿¡°Ô ¸¹´Ù. Áö°¢Àå¾Ö´Â ¾ø´Ù. ´ë°³ ¼Õ ±ÙÀ°ÀÇ ±Ù·Â ÀúÇÏ¿Í À§ÃàÀÌ µÇ¸é¼­ Â÷Ãû ÁøÇàÇÏ¿© ÆÈ, ¾î±úÀÇ ±ÙÀ°¿¡ ¹ÌÄ£´Ù. ´õ ³ª¾Æ°¡ ÇÏÁöÀÇ ±ÙÀ°ÀÌ À§ÃàÇϰųª, ±¸À½, ¿¬Çϱٵµ ħ¹üµÇ¾î ±¸¸¶ºñ Áõ»óÀ» ³ªÅ¸³½´Ù. ½ÉºÎ¹Ý»ç´Â Åë»ó Ç×ÁøÇÏ°í ±ÙÀ°¿¡´Â ¼¶À¯¼º ¿¬ÃàÀ» º¸°Ô µÈ´Ù. ƯȿÀûÀÎ Ä¡·á¹ýÀº ¾ø°í ¿¹Èİ¡ ºÒ·®ÇÏ¸ç Æò±Õ 3³â, ´ëºÎºÐ 5³â À̳»¿¡ »ç¸ÁÇÑ´Ù.
  • annular sclerosis
    À±»ó °æÈ­Áõ
    ôÃß ÁÖÀ§¿¡ ´ë»óÀ¸·Î »ý±â´Â °æÈ­Áõ.
  • areolar choroidal sclerosis
    ¿øÇü ¸Æ¶ô¸· °æÈ­
  • condylar sclerosis
    °úµÎ °æÈ­Áõ
  • dentinal sclerosis
    »ó¾Æ ¼¼°ü °æ»ö, »ó¾ÆÁú °æÈ­Áõ
    Àڱؿ¡ ´ëÇÑ »ó¾ÆÁúÀÇ ¹ÝÀÀÀ¸·Î¼­ »ó¾Æ¼¼°üÀÇ Á¡Â÷ÀûÀÎ ¼®È¸È­¸¦ ¸»ÇÑ´Ù. ÀÌ´Â ¿ì½Ä, ±³¸ðÁõ, ¶Ç´Â Ä¡°æºÎ ¸¶¸ðÁõ¿¡ ÀÇÇØ »ó¾ÆÁúÀÌ ±¸°­ ȯ°æ¿¡ ¸¸¼ºÀûÀ¸·Î ³ëÃâµÇ´Â °æ¿ì ¹ß»ýµÇ¸ç ³ëÃâµÈ »ó¾ÆÁúÀº À¯¸®¿Í °°ÀÌ ¹Ý¦À̴ ǥ¸é Áú°¨À» °®°í ÀÖ´Ù. ÇÑÆí, »ó¾ÆÁú¿¡ ´ëÇÑ ¿­Àû, È­ÇÐÀû, Ã˰¢ÀûÀÎ Àڱؿ¡ ´ëÇØ Ä¡¼ö¸¦ È¿°úÀûÀ¸·Î º¸È£ÇÏ´Â ÀÛ¿ëÀ» Áö´Ï°í ÀÖ´Ù.
  • diffuse sclerosis
    ¹ü¹ß¼º °æÈ­Áõ
  • lichen sclerosis et atrophicus
    °æÈ­ À§Ã༺ ÆíÆò ż±
    ¸¸¼º À§Ã༺ÀÇ ÇǺΠÁúȯÀ¸·Î, ºÎÁ¤ÇüÀÇ ÆíÆòÇÑ ±¸ÁøÀÌ °¢Àü°ú ÇÔ¿ä¿¡ ÀÇÇÏ¿© ´ÙÇü¼ºÀ» ³ªÅ¸³»´Â °ÍÀÌ Æ¯Â¡ÀÌ´Ù. ³²ÀÚ´Â À½°æ¿¡ ¹ß»ýÇÏ´Â Æó»ö¼º °ÇÁ¶¼º ±ÍµÎ¿°°ú ¿©ÀÚÀÇ ¿ÜÀ½ºÎ¿¡ ¹ßº´ÇÏ´Â ¿ÜÀ½ À§Ãà ÁõÀÇ °¡Àå ÈçÇÑ ¿øÀÎÀÌ µÈ´Ù.
  • muscle sclerosis
    ±Ù °æÈ­Áõ
  • posterolateral sclerosis syndrome
    ÈÄ»è Ãø»è °æÈ­Áõ ÁõÈıº
  • primary lateral sclerosis
    ¿ø¹ß¼º Ãø»ö °æÈ­Áõ
  • progressive systemic sclerosis
    ÁøÇ༺ Àü½Å °æÈ­Áõ, ÁøÇ༺ Àü½Å¼º °æÈ­Áõ, ÁøÇ༺ Àü½Å¼º °øÇÇÁõ
  • pulmonary sclerosis
    Æó °æÈ­Áõ
  • pulp sclerosis
    Ä¡¼ö ¼®È¸Áõ
    Ä¡¼ö°­°ú Ä¡±Ù°ü¿¡¼­ ¹ß»ýµÇ´Â ¶Ç ´Ù¸¥ ÇüÅÂÀÇ ¼®È¸È­ Çö»óÀÌ´Ù. Ä¡¼ö¼®°ú´Â ´Þ¸® Ä¡¼ö ¼®È¸ÁõÀº ´õ¿í ±¤¹üÀ§ÇÑ ÇüÅÂÀÌ´Ù. ¿øÀÎÀº Àß ¾Ë·ÁÁ® ÀÖÁö ¾ÊÀ¸³ª ¿¬·É°ú Å« °ü°è°¡ ÀÖ´Â °Í °°´Ù. 10-20¼¼ÀÇ ¸ðµç Ä¡¾Æ Áß 60%, 50-70¼¼ÀÇ ¸ðµç Ä¡¾Æ Áß 90%°¡ Á¶Á÷ÇÐÀûÀ¸·Î Ä¡¼ö ¼®È¸ÁõÀÇ ¼Ò°ßÀ» º¸¿´°í Á¶Á÷ÇÐÀûÀ¸·Î ¼®È¸È­ÀÇ ÇüÅ´ ¹«Á¤ÇüÀÌ°í ¹«±¸Á¶¸¦ º¸ÀÌÁö¸¸ Ä¡¼ö¿¡ ÀÖ´Â Ç÷°ü°ú ½Å°æ¿¡ ÆòÇàÇÑ ´ë»ó
  • sclerosis
    °æÈ­, °æÈ­Áõ, °ñ °æÈ­Áõ, °æ°á, °æÈ­
    ƯÈ÷ ¿°Áõ ¹× °£Áú Áúȯ¿¡ ÀÇÇØ¼­ »ý±â´Â ºÎºÐÀû °æÈ­·Î¼­, ÀÌ ¿ë¾î´Â ÁÖ·Î °áÇÕ Á¶Á÷ÀÇ °úÇü¼º¿¡ ÀÇÇÑ ½Å°æ°èÀÇ °æÈ­ ¶Ç´Â Ç÷°üÀÇ °æÈ­¿¡ ´ëÇØ¼­ »ç¿ëµÈ´Ù.
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
Canavan's sclerosis Autosomal recessive degenerative disease of infancy; mostly in Jewish infants; onset typically within first 3-4 months of birth, consisting of blindness, psychomotor regression, enlarged head, optic atrophy, hypotonia, spasticity, increased N-acetylaspartic acid urinary excretion. MRI shows enlarged brain, decreased attenuation of cerebral and cerebellar white matter, and normal ventricles. Pathologically, there is increased brain volume and weight, and spongy degeneration in the subcortical white matter.
See: leukodystrophy.
Synonym: Canavan's sclerosis, Canavan-van Bogaert-Bertrand disease, spongy degeneration of infancy.
(05 Mar 2000)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
canavan disease Spongy degeneration of cerebral white matter, a rare autosomal recessive form of leukodystrophy. It is characterised by early onset, widespread demyelination and vacuolation of the white matter that gives rise to a spongy appearance, severe mental retardation, megalocephaly, atony of the neck muscles, spasticity of the extremities, and blindness. Death occurs at about 18 months of age.
(12 Dec 1998)
Canavan, Myrtelle <person> U.S. Pathologist, 1879-1953.
See: Canavan's disease, Canavan's sclerosis, Canavan-van Bogaert-Bertrand disease.
(05 Mar 2000)
Canavan's disease Autosomal recessive degenerative disease of infancy; mostly in Jewish infants; onset typically within first 3-4 months of birth, consisting of blindness, psychomotor regression, enlarged head, optic atrophy, hypotonia, spasticity, increased N-acetylaspartic acid urinary excretion. MRI shows enlarged brain, decreased attenuation of cerebral and cerebellar white matter, and normal ventricles. Pathologically, there is increased brain volume and weight, and spongy degeneration in the subcortical white matter.
See: leukodystrophy.
Synonym: Canavan's sclerosis, Canavan-van Bogaert-Bertrand disease, spongy degeneration of infancy.
(05 Mar 2000)
Canavan-van Bogaert-Bertrand disease Autosomal recessive degenerative disease of infancy; mostly in Jewish infants; onset typically within first 3-4 months of birth, consisting of blindness, psychomotor regression, enlarged head, optic atrophy, hypotonia, spasticity, increased N-acetylaspartic acid urinary excretion. MRI shows enlarged brain, decreased attenuation of cerebral and cerebellar white matter, and normal ventricles. Pathologically, there is increased brain volume and weight, and spongy degeneration in the subcortical white matter.
See: leukodystrophy.
Synonym: Canavan's sclerosis, Canavan-van Bogaert-Bertrand disease, spongy degeneration of infancy.
(05 Mar 2000)
Alzheimer's sclerosis Hyaline degeneration of the medium and smaller blood vessels of the brain.
(05 Mar 2000)
amyotrophic lateral sclerosis A serious neurologic disease that results from the progressive degeneration of the motor neurons.
(27 Sep 1997)
amyotropic lateral sclerosis A chronic progressive disease of motor neurons (the nerves that come from the spinal cord to supply electrical energy to the muscles).
(12 Dec 1998)
arterial sclerosis <cardiology, disease> Imprecise term for various disorders of arteries, particularly hardening due to fibrosis or calcium deposition, often used as a synonym for atherosclerosis.
(17 Oct 1997)
arteriocapillary sclerosis Arteriosclerosis, especially of the finer vessels.
(05 Mar 2000)
arteriolar sclerosis <cardiology, disease> Sclerosis and thickening of the walls of the smaller arteries (arterioles). Hyaline arteriolosclerosis, in which there is homogeneous pink hyaline thickening of the arteriolar walls, is associated with benign nephrosclerosis.
Hyperplastic arteriolosclerosis, in which there is a concentric thickening with progressive narrowing of the lumina may be associated with malignant hypertension, nephrosclerosis and scleroderma.
(17 Oct 1997)
bone sclerosis <medicine> A condition of bone cartilage occurring in certain diseases of these tissues, in which they acquire an unnatural density, and come to resemble ivory.
Origin: L. Eburnus of ivory, fr. Ebur ivory: cf. F. Eburnation. See Ivory.
Source: Websters Dictionary
(01 Mar 1998)
valvular sclerosis Fibrosis, often with calcification of valves, considered to be an aging change and not due to primary valvular disease.
(05 Mar 2000)
vascular sclerosis <cardiology, disease> Imprecise term for various disorders of arteries, particularly hardening due to fibrosis or calcium deposition, often used as a synonym for atherosclerosis.
(17 Oct 1997)
mantle sclerosis A common cerebral lesion in the palsied states of early life characterised by nodular cortical atrophy.
(05 Mar 2000)
glomerular sclerosis Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes.
Synonym: glomerular sclerosis.
Origin: Glomerulus + G. Sklerosis, hardness
(05 Mar 2000)
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