| 영문 | lymphocyte | 한글 | 림프구 |
|---|---|---|---|
| 설명 | 면역기능을 담당하는 세포. 골수에서 만들어지며, 림프구는 크게 2가지로 대분된다. 이른바 T림프세포, B림프세포로 나뉘어지게 된다. T림프세포는 세포성면역에 관여하며, 주로 바이러스병에 대한 면역기능이나, 알레르기(면역반응 4번형 등) 등에 관여한다. 이에 비해 B림프세포는 체액성면역에 관여하여, 항원 항체 반응을 일으키는 항체를 생산하고 주로 세균감염에 대한 면역기능을 담당한다. |
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| 영문 | T-lymphocyte | 한글 | 티 림프구 |
|---|---|---|---|
| 설명 | 림프계세포(림프구)는 크게 2가지로 대분된다. 이른바 T림프세포(T-cell), B림프세포(B-cell)로 나뉘어진다. T림프세포는 세포성 면역에 관여하며, 주로 바이러스병에 대한 면역기능이나, 알레르기 등에 관여한다. 이에 비해 B림프세포는 체액성 면역에 관여하여, 항원 항체 반응을 일으키는 항체를 생산하고 주로 세균성 질환에 대한 면역 기능을 담당한다. T-림프구는 면역기능에 가장 중요한 역할을 하는 세포로서 세포면역을 담당하며 B-cell의 작용을 조절하는 기능도 있다. 골수에서 생성되어 가슴샘에서 성숙된다. 크게 보조T세포(helper T-cell: 면역작용의 발생을 보조한다)와 T세포(suppressor T-cell: 면역작용의 발생을 억제한다)로 구분되며 이들은 세포 표면에 분포하는 항원에 의해서 식별될 수 있다. |
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| ICL | Idiopathic CD4 + T Lymphocytopenia |
|---|---|
| CD4 | HIV helper cell count |
| ICL | idiopathic CD4 T-cell lymphocytopenia; iris-clip lens; isocitrate lyase |
| CTL | cervico-thoraco-lumbar; control; cytolytic C lymphocyte; cytotoxic T-lymphocyte |
| HLA-LD | human lymphocyte antigen-lymphocyte defined |
| CD4+ | CD4 positive |
|---|---|
| h-CD4 | human CD4 |
| ICL | Idiopathic CD4 T lymphocytopenia |
| rCD4 | Recombinant CD4 |
| rsCD4 | Recombinant soluble CD4 |
| CD4 lymphocyte | A specific type of lymphocyte, derived from the thymus gland, that plays an important role in cellular immunity. T4 lymphocytes (CD4 cells) are decreased (absolute counts less than 200) in patients with AIDS resulting in compromised immune function. (27 Sep 1997) |
|---|---|
| CD4 lymphocyte count | A count of the number of CD4-positive lymphocytes in the blood. Determination requires the use of a fluorescence-activated flow cytometer. (12 Dec 1998) |
| lymphocyte lymphocyte | A type of non-granular antibodies. (09 Oct 1997) |
|---|---|
| absolute CD4 count | The number of helper T-lymphocytes in a cubic millimeter of blood. With HIV, the absolute CD4 count declines as the infection progresses. The absolute CD4 count is frequently used to monitor the extent of immune suppression in persons with HIV. Also called a T4 count. (12 Dec 1998) |
| antigens, CD4 | <immunology> 55-kD glycoproteins originally defined as differentiation antigens on T-lymphocytes, but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (major histocompatibility complex) class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. Cd4 antigens also serve as HIV receptors, binding directly to the envelope protein gp120 on HIV. The protein structure on the surface of a human cell that allows HIV to attach, enter, and thus infect a cell. CD4 receptors are present on CD4 cells (helper T-cells), macrophages and dendritic cells, among others. Normally, CD4 acts as an accessory molecule, forming part of larger structures (such as the T-cell receptor) through which Tcells and other cells signal each other. (12 Dec 1998) |
| CD4 | <immunology> 55-kD glycoproteins originally defined as differentiation antigens on T-lymphocytes, but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (major histocompatibility complex) class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. Cd4 antigens also serve as HIV receptors, binding directly to the envelope protein gp120 on HIV. The protein structure on the surface of a human cell that allows HIV to attach, enter, and thus infect a cell. CD4 receptors are present on CD4 cells (helper T-cells), macrophages and dendritic cells, among others. Normally, CD4 acts as an accessory molecule, forming part of larger structures (such as the T-cell receptor) through which Tcells and other cells signal each other. (12 Dec 1998) |
| CD4/CD8 count | The ratio of the number of helper-inducer T lymphocytes to cytotoxic-suppressor T lymphocytes, as measured by monoclonal antibodies to the CD4 surface antigen found on helper-inducer T-cells, and the CD8 surface antigen found on cytotoxic-suppressor T-cells. In healthy individuals, the H/S ratio ranges between 1.6 and 2.2.When the body mounts an immune response, as against a virus or a transplant, the ratio is almost always reduced because of a decrease in the number of circulating helper-inducer cells and an increase in suppressor cells. The CD4/CD8 count has been used to monitor for signs of organ rejection after transplants, and more recently has become a tool for assessing the relative condition of HIV patients. With the CD4 absolute count and the CD4 lymphocyte percentage, it provides a way of gauging the progression from HIV to AIDS. (05 Mar 2000) |
| CD4:CD8 ratio | The ratio of CD4 to CD8 cells. A common measure of immune system status that is around two in healthy individuals. The ratio of T-lymphocytes that express the CD4 antigen to those that express the CD8 antigen. This value is commonly assessed in the diagnosis and staging of diseases affecting the immune system including HIV infection. (12 Dec 1998) |
| CD4 cell | T helper cells which are targets for HIV infection. (09 Oct 1997) |
| CD4 cell count | The most commonly used surrogate marker for assessing the state of the immune system. As CD4 cell count declines, the risk of developing opportunistic infections increases. The normal range for CD4 cell counts is 500 to 1500 per cubic millimetre of blood. CD4 count should be rechecked at least every six to twelve months if CD4s are greater than 500/mm3. If the count is lower, testing every three months is advised. (09 Oct 1997) |
| CD4 count, absolute | The number of helper T-lymphocytes in a cubic millimeter of blood. With HIV, the absolute CD4 count declines as the infection progresses. The absolute CD4 count is frequently used to monitor the extent of immune suppression in persons with HIV. Also called a T4 count. (12 Dec 1998) |
| CD4 immunoadhesins | <immunology> Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the fc portion of immunoglobulins. These have potential use in the therapy of aids since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and fc receptor-binding functions of immunoglobulin. (12 Dec 1998) |
| CD4-positive T-lymphocytes | A critical subpopulation of regulatory T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the t4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes, which includes both the helper-inducer (T-lymphocytes, helper-inducer) and suppressor-inducer (T-lymphocytes, suppressor-inducer) T-cells. (12 Dec 1998) |
| t-lymphocytopenia, idiopathic CD4-positive | Reproducible depletion of CD4+ lymphocytes below 300 per cubic millimeter in the absence of HIV infection or other known causes of immunodeficiency. This is a rare, heterogeneous syndrome and does not appear to be caused by a transmissible agent. (12 Dec 1998) |
| antigens, differentiation, b-lymphocyte | Membrane antigens associated with maturation stages of B-lymphocytes, often expressed in tumours of B-cell origin. (12 Dec 1998) |
| antigens, differentiation, t-lymphocyte | Antigens expressed on the cell membrane of T-lymphocytes during differentiation, activation, and normal and neoplastic transformation. Their phenotypic characterization is important in differential diagnosis and studies of thymic ontogeny and T-cell function. (12 Dec 1998) |
| bare lymphocyte syndrome | <syndrome> Absence of HLA antigens on peripheral mononuclear cells, which may result in immunodeficiency. (05 Mar 2000) |
Synonyms : CD4 Cell Counts, CD4 Counts, CD4+ Cell Counts, CD4+ Counts, CD4 Cell Count, CD4 Count, CD4 Lymphocyte Counts, CD4+ Cell Count, CD4+ Count, Count, T4 Lymphocyte, Counts, T4 Lymphocyte, Lymphocyte Count, T4, Lymphocyte Counts, CD4, Lymphocyte Counts, T4
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|