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CD30L CD30 ligand
CD34(+) CD34 positive
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TCR-CD3 T cell receptor-CD3
TCR CD3--T-cell receptor
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  • muromonab-CD3
    ¹Â·Î¸ð³ªºê-CD3
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CD3 <immunology> A complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (receptors, antigen, T-cell). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (receptors, antigen, T-cell, gamma-delta).
(12 Dec 1998)
CD30 <immunology> Differentiation antigens normally present in a small number of cells in the lymph nodes and tonsils in vivo, but also capable of being induced in a wide range of cells in vitro. They are clinically useful as tumour markers for ki-1 lymphoma (lymphoma, large-cell, ki-1) and some cases of lymphomatoid papulosis, mycosis fungoides, and hodgkin's disease.
(12 Dec 1998)
CD31 <immunology> Cell adhesion molecules present on virtually all monocytes, platelets, and granulocytes. Cd31 is highly expressed on endothelial cells and concentrated at the junctions between them.
(12 Dec 1998)
CD34 <immunology> Glycoproteins found on immature haematopoietic cells and endothelial cells. They are the only molecules to date whose expression within the blood system is restricted to a small number of progenitor cells in the bone marrow.
(12 Dec 1998)
CD36 <immunology> Leukocyte differentiation antigens and major platelet membrane glycoproteins present on monocytes, endothelial cells, platelets, mammary epithelial cells, and a variety of cultured cell lines. They play major roles in adhesion phenomena, signal transduction, and haematopathology. Cd36 is also the receptor for thrombospondin and malaria-infected erythrocytes.
(12 Dec 1998)
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antigens, CD3 <immunology> A complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (receptors, antigen, T-cell). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (receptors, antigen, T-cell, gamma-delta).
(12 Dec 1998)
receptor-CD3 complex, antigen, T-cell Molecule composed of the non-covalent association of the T-cell antigen receptor (receptors, antigen, T-cell) with the CD3 complex (antigens, CD3). This association is required for the surface expression and function of both components. The molecule consists of up to seven chains: either the alpha/beta or gamma/delta chains of the T-cell receptor, and four or five chains in the CD3 complex.
(12 Dec 1998)
muromonab-CD3 <chemical> Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/ti). This biochemically purified IgG immunoglobulin is obtained through the fusion of mouse myeloma cells to lymphocytes from immunised animals to produce hybridomas that secrete specific antibodies to the t3 (CD3) antigens of human T-lymphocytes. It is often used as an immunosuppressive agent in transplantation.
Pharmacological action: immunosuppressive agents.
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 1 ÆäÀÌÁö: 1
  • CD30 Ligand - »õâ A membrane-bound tumor necrosis family member found primarily on activated T-LYMPHOCYTES that binds specifically to CD30 ANTIGEN. It may play a role in INFLAMMATION and immune regulation.
    Synonyms : CD153 Antigen, TNF Superfamily, Member 8, Antigen, CD153
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