| TCC | terminal C5b-9 complement complex |
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| C5b,6,7 |
a trimolecular complex of C5b, C6, and C7 that binds to cell membranes in the formation of the membrane attack complex; it can be inhibited by binding by vitronectin, which yields an inactivated complex unable to bind to membranes. C5b,6,7 is also a chemotactic factor for neutrophils. Sometimes abbreviated C5b7.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| C5b,6,7,8 |
a complex generated by binding of C8 to membrane-bound C5b,6,7; it causes a slow leakage of the cell membrane. Sometimes abbreviated C5b8.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| C5b,6,7,8,9 |
the complete membrane attack complex (cytolytic agent) of the complement system, generated by addition of multiple molecules of C9 to C5b,6,7,8; this complex has a hydrophilic center that allows the rapid passage of water and ions through the cell membrane, causing osmotic lysis of the cell. Sometimes abbreviated C5b9 or C5b9n.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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