| BN | Buprenorphine |
|---|---|
| BUP | Buprenorphine |
| buprenorphine | <chemical> 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol. A derivative of the opioid alkaloid thebaine that is a more potent and longer lasting analgesic than morphine. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use. Pharmacological action: analgesics, opioid, narcotic antagonists, narcotics. Chemical name: 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))- (12 Dec 1998) |
|---|---|
| buprenorphine hydrochloride | C29H41NO4-HCl;a semisynthetic opioid analgesic used for relief of moderate to severe pain. (05 Mar 2000) |
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