| Bunyaviridae | <molecular biology, virology> A family of arboviruses composed of more than 200 viruses, including the genera: Bunyavirus, Hantavirus, Phlebovirus, Nairovirus, Uukuvirus. These single-stranded RNA enveloped viruses are spherical or oval and measure 90-100nm in diameter and are all sensitive to lipid solvents and detergents. They infect vertebrates and arthropods and some genera contain organisms causing serious disease for example viral haemorrhagic fever. (18 Nov 1997) |
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| bunyaviridae infections | Virus diseases caused by the bunyaviridae. (12 Dec 1998) |
Synonyms :
Synonyms : Infections, Bunyaviridae, Infections, Bunyavirus, Bunyaviridae Infection, Bunyavirus Infection
| Bunyaviridae |
the bunyaviruses: a family of RNA viruses having a spherical or oval virion 80120 nm in diameter consisting of a lipid bilayer envelope, with glycoprotein surface projections 510 nm long and 1012 nm across in hexagonal arrangement, surrounding three loosely helical nucleocapsids. The genome consists of three molecules of circular negative-sense or ambisense single-stranded RNA, designated L, M, and S (total MW 4.88×106, size of total genome 1120 kb). Viruses contain four major structural polypeptides, including a transcriptase, and are sensitive to lipid solvents and detergents. Replication occurs in the cytoplasm and assembly is by budding through the smooth membrane of the Golgi apparatus. Host ranges vary; transmission is generally by arthropod vectors, although transmission by aerosols and avian vectors sometimes occurs. Genera include Bunyavirus, Hantavirus, Nairovirus, Phlebovirus, and Tospovirus.
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